Effect of Thermal Treatment on the Photocatalytic Activity in Visible Light of TiO<Subscript>2</Subscript>-W Flame Spray Synthesised Nanopowders

Effect of W doping as well as a thermal treatment on the structural and photocatalytic properties of TiO₂ produced by flame spray synthesis (FSS) were the subject of investigation. Structural properties were studied by means of X-ray diffraction (XRD), BET adsorption isotherm and transmission electron microscopy (TEM). The surface condition was investigated by X-ray photoelectron spectroscopy (XPS) and differential scanning calorimetry (DSC) and differential thermal and thermogravimetric analysis (DTA-TGA). The photocatalytic properties were studied by optical measurements and photodecomposition of methylene blue under visible irradiation. It was found that the photoactivity in the visible region was enhanced significantly by the W-doping as well as by additional thermal treatment of those nanopowders. The obtained TiO₂-W nanopowders exhibited higher performance under visible light than P25.     

Adenylate Kinase and AMP Signaling Networks: Metabolic Monitoring,Signal Communication and Body Energy Sensing

Adenylate kinase and downstream AMP signaling is an integrated metabolic monitoring system which reads the cellular energy state in order to tune and report signals to metabolic sensors. A network of adenylate kinase isoforms (AK1-AK7) are distributed throughout intracellular compartments, interstitial space and body fluids to regulate energetic and metabolic signaling circuits, securing efficient cell energy economy, signal communication and stress response. The dynamics of adenylate kinase-catalyzed phosphotransfer regulates multiple intracellular and extracellular energy-dependent and nucleotide signaling processes, including excitation-contraction coupling, hormone secretion, cell and ciliary motility, nuclear transport, energetics of cell cycle, DNA synthesis and repair, and developmental programming. Metabolomic analyses indicate that cellular, interstitial and blood AMP levels are potential metabolic signals associated with vital functions including body energy sensing, sleep, hibernation and food intake. Either low or excess AMP signaling has been linked to human disease such as diabetes, obesity and hypertrophic cardiomyopathy. Recent studies indicate that derangements in adenylate kinase-mediated energetic signaling due to mutations in AK1, AK2 or AK7 isoforms are associated with hemolytic anemia, reticular dysgenesis and ciliary dyskinesia. Moreover, hormonal, food and antidiabetic drug actions are frequently coupled to alterations of cellular AMP levels and associated signaling. Thus, by monitoring energy state and generating and distributing AMP metabolic signals adenylate kinase represents a unique hub within the cellular homeostatic network.     

Novel supports for nickel-based catalysts for the partial oxidation of methane

Zirconia-supported nickel catalysts with different amounts of aluminum (Al/Zr = 0.2, 1 and 2) were studied in this work in order to find alternative supports for nickel-based catalysts for the partial oxidation of methane. This reaction is a promising route for producing hydrogen and syngas for different applications. Samples were prepared by precipitation and impregnation techniques, characterized by several techniques and evaluated in the partial oxidation of methane in the range of 450–750 °C and 1 atm. It was found that aluminum affects the textural and catalytic properties of zirconia-supported nickel catalysts. The tetragonal phase of zirconia was stabilized by aluminum and gamma-alumina was also found in the aluminum-richest samples. Aluminum increased the porosity and the specific surface area of the solids. The catalytic activity also increased with the amount of aluminum in solids probably due to the stronger interaction of nickel with the support, which slowly generates active sites during the reduction step. The methane conversion and hydrogen selectivity increased with temperature, indicating no deactivation. The hydrogen to carbon monoxide molar ratio decreased due to aluminum but was not significantly affected by temperature. The coke produced was not harmful to the catalysts and aluminum affected its amount, although no simple relationship was found between these parameters. The most promising catalyst was the sample with aluminum to zirconium molar ratio of 2, which showed high activity and hydrogen selectivity and was stable under the reaction condition.     

Intervertebral Disc Regeneration Injection of a Cell-Loaded Collagen Hydrogel in a Sheep Model

Degenerated intervertebral discs (IVDs) were treated with autologous adipose-derived stem cells (ASC) loaded into an injectable collagen scaffold in a sheep model to investigate the implant’s therapeutic potential regarding the progression of degeneration of previously damaged discs. In this study, 18 merino sheep were subjected to a 3-step minimally invasive injury and treatment model, which consisted of surgically induced disc degeneration, treatment of IVDs with an ASC-loaded collagen hydrogel 6 weeks post-operatively, and assessment of the implant’s influence on degenerative tissue changes after 6 and 12 months of grazing. Autologous ASCs were extracted from subcutaneous adipose tissue and cultivated in vitro. At the end of the experiment, disc heights were determined by µ-CT measurements and morphological tissue changes were histologically examined.Histological investigations show that, after treatment with the ASC-loaded collagen hydrogel implant, degeneration-specific features were observed less frequently. Quantitative studies of the degree of degeneration did not demonstrate a significant influence on potential tissue regeneration with treatment. Regarding disc height analysis, at both 6 and 12 months after treatment with the ASC-loaded collagen hydrogel implant a stabilization of the disc height can be seen. A complete restoration of the intervertebral disc heights however could not be achieved.The reported injection procedure describes in a preclinical model a translational therapeutic approach for degenerative disc diseases based on adipose-derived stem cells in a collagen hydrogel scaffold. Further investigations are planned with the use of a different injectable scaffold material using the same test model.     

Reduced‐scale test to assess the effect of fire barriers on the flaming combustion of cored composites: An upholstery‐material case study

Herein, we describe a reduced‐scale test (“Cube” test), measuring the fire performance of specimens including a fire barrier (FB) and a flammable core material, which acts as the main fuel load. The specimen is intended to reproduce a cross‐section of a composite product where heat/mass transfer occurs primarily in a direction perpendicular to the FB. The Cube test procedure and benefits are discussed in this work by adopting residential upholstery furniture as an exemplary study. One flexible polyurethane foam, one polypropylene cover fabric, and 10 commercially available FBs were selected. They were used to compare the fire performance of FBs, measured in terms of peak of heat release rate, in the ASTM E1474‐14 standard test and the newly developed Cube test. Edge effects severely affected the performance of FBs in the ASTM E1474‐14 standard test but not in the Cube test. Furthermore, appropriate test conditions were determined in the Cube test to measure the so‐called “wetting point,” that is, the time and value of heat release rate measured when flammable liquid products were first observed on the bottom of the specimen. The relevance of the “wetting point” in terms of full‐scale fire performance and failure mechanism of FBs is discussed.     

Exchange Interactions at the Interface FMIAFM Nanocomposite Obtained by Mechanochemical Synthesis

This paper presents a study of the relationship between the magnetic properties and microstructure of nanocomposite Ni/MnO, Ni/CoO, Co/MnO, Co/CoO. The objective is to understand how the coupling interface FM/AFM （ferromagnetic/anti-ferromagnetic） manifests itself in magnetic response of these materials to an applied field. Sample preparation was performed using mechanochemical synthesis by means of a ball mill planetary type high power at normal atmosphere. The characterization was done by XRD （X-ray diffraction）, SEM （scanning electron microscopy） and VSM （vibrating sample magnetometry）. Analyzing the XRD peaks of the samples studied, there was a decrease in the average particle diameter with increasing milling time, which is important in the magnetic interactions of the atoms of the surface. In addition, the diffraction pattern showed formation of new phases by oxidation interfering with the magnetic measurements. Analyses by SEM show chipboard multiform nano- and micrometer-sized grains on the surface of the clusters being responsible for the interaction. The magnetic measurements show a strong coupling between the phases present in nanocomposites showing once again that the MS （mechanosynthesis） is a powerful technique for this kind of purpose. The effect of the decrease in crystallite size leads to large variations of magnetic properties of the material which have been specifically observed changes in HC （coercive field） in the RM （remanent magnetization） and SM （saturation magnetization）. The decrease in crystallite size in the course of grinding intensifies the effects that depend on the surface-to-volume ratio of the material. M vs. T measures were taken for different values of applied field and found a jump in the moment of the sample near the N6el temperature of the antiferromagnetic.     

A Mathematical Model for the Velocity Profile Internally to a Conical Diffuser

The use of diffusers around the horizontal-axis wind turbines has been widely studied since the diffuser improves the power coefficient of the turbine and it is often called DAWTs （diffuser augmented wind turbines）.Turbines using diffuser are called DWATs （Diffuser Augmented Turbines）,and have efficiency bigger than the Betz limit （maximum energy flow extracted = 59.26%）. Thus, this study presents a mathematical model describing the behavior of the velocity profile internally to a diffuser according to the characteristics of flow and geometry of a conical diffuser. The results are compared with experimental data and show good agreement.