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41.
Andrzej Taube Robert Mroczyński Katarzyna Korwin-Mikke Sylwia Gierałtowska Jan Szmidt Anna Piotrowska 《Materials Science and Engineering: B》2012,177(15):1281-1285
In this work, we report on effects of post-deposition annealing on electrical characteristics of metal–insulator–semiconductor (MIS) structures with HfO2/SiO2 double gate dielectric stacks. Obtained results have shown the deterioration of electro-physical properties of MIS structures, e.g. higher interface traps density in the middle of silicon forbidden band (Ditmb), as well as non-uniform distribution and decrease of breakdown voltage (Ubr) values, after annealing above 400 °C. Two potential hypothesis of such behavior were proposed: the formation of interfacial layer between hafnia and silicon dioxide and the increase of crystallinity of HfO2 due to the high temperature treatment. Furthermore, the analysis of conduction mechanisms in investigated stacks revealed Poole–Frenkel (P–F) tunneling at broad range of electric field intensity. 相似文献
42.
Andrzej M.J. Skulimowski 《International journal of systems science》2014,45(1):39-59
In this article, we will investigate the properties of a compromise solution selection method based on modelling the consequences of a decision as factors influencing the decision making in subsequent problems. Specifically, we assume that the constraints and preference structures in the (k?+?1)st multicriteria optimisation problem depend on the values of criteria in the k-th problem. To make a decision in the initial problem, the decision maker should take into account the anticipated outcomes of each linked future decision problem. This model can be extended to a network of linked decision problems, such that causal relations are defined between the time-ordered nodes. Multiple edges starting from a decision node correspond to different future scenarios of consequences at this node. In addition, we will define the relation of anticipatory feedback, assuming that some decision makers take into account the anticipated future consequences of their decisions described by a network of optimisers ? a class of information processing units introduced in this article. Both relations (causal and anticipatory) form a feedback information model, which makes possible a selection of compromise solutions taking into account the anticipated consequences. We provide constructive algorithms to solve discrete multicriteria decision problems that admit the above preference information structure. An illustrative example is presented in Section 4. Various applications of the above model, including the construction of technology foresight scenarios, are discussed in the final section of this article. 相似文献
43.
Artur Bekaa Wodzimierz Potek Dorota Siwicka-Gieroba Joanna Soek-Pastuszka Romuald Bohatyrewicz Jowita Biernawska Katarzyna Kotfis Magdalena Bielacz Andrzej Jaroszyski Wojciech Dabrowski 《International journal of molecular sciences》2022,23(13)
Brain injury, especially traumatic brain injury (TBI), may induce severe dysfunction of extracerebral organs. Cardiac dysfunction associated with TBI is common and well known as the brain–heart crosstalk, which broadly refers to different cardiac disorders such as cardiac arrhythmias, ischemia, hemodynamic insufficiency, and sudden cardiac death, which corresponds to acute disorders of brain function. TBI-related cardiac dysfunction can both worsen the brain damage and increase the risk of death. TBI-related cardiac disorders have been mainly treated symptomatically. However, the analysis of pathomechanisms of TBI-related cardiac dysfunction has highlighted an important role of melatonin in the prevention and treatment of such disorders. Melatonin is a neurohormone released by the pineal gland. It plays a crucial role in the coordination of the circadian rhythm. Additionally, melatonin possesses strong anti-inflammatory, antioxidative, and antiapoptotic properties and can modulate sympathetic and parasympathetic activities. Melatonin has a protective effect not only on the brain, by attenuating its injury, but on extracranial organs, including the heart. The aim of this study was to analyze the molecular activity of melatonin in terms of TBI-related cardiac disorders. Our article describes the benefits resulting from using melatonin as an adjuvant in protection and treatment of brain injury-induced cardiac dysfunction. 相似文献
44.
Elbieta U. Stolarczyk Weronika Strzempek Marta aszcz Andrzej Le Elbieta Menaszek Krzysztof Stolarczyk 《International journal of molecular sciences》2022,23(14)
Isoflavonoids such as genistein (GE) are well known antioxidants. The predictive biological activity of structurally new compounds such as thiogenistein (TGE)–a new analogue of GE–becomes an interesting way to design new drug candidates with promising properties. Two oxidation strategies were used to characterize TGE oxidation products: the first in solution and the second on the 2D surface of the Au electrode as a self-assembling TGE monolayer. The structure elucidation of products generated by different oxidation strategies was performed. The electrospray ionization mass spectrometry (ESI-MS) was used for identifying the product of electrochemical and hydrogen peroxide oxidation in the solution. Fourier transform infrared spectroscopy (FT-IR) with the ATR mode was used to identify a product after hydrogen peroxide treatment of TGE on the 2D surface. The density functional theory was used to support the experimental results for the estimation of antioxidant activity of TGE as well as for the molecular modeling of oxidation products. The biological studies were performed simultaneously to assess the suitability of TGE for antioxidant and antitumor properties. It was found that TGE was characterized by a high cytotoxic activity toward human breast cancer cells. The research was also carried out on mice macrophages, disclosing that TGE neutralized the production of the LPS-induced reactive oxygen species (ROS) and exhibits ABTS (2,2′-azino-bis-3-(ethylbenzothiazoline-6-sulphonic acid) radical scavenging ability. In the presented study, we identified the main oxidation products of TGE generated under different environmental conditions. The electroactive centers of TGE were identified and its oxidation mechanisms were proposed. TGE redox properties can be related to its various pharmacological activities. Our new thiolated analogue of genistein neutralizes the LPS-induced ROS production better than GE. Additionally, TGE shows a high cytotoxic activity against human breast cancer cells. The viability of MCF-7 (estrogen-positive cells) drops two times after a 72-h incubation with 12.5 μM TGE (viability 53.86%) compared to genistein (viability 94.46%). 相似文献
45.
Andrzej Filinski 《LISP and Symbolic Computation》1994,7(1):11-37
In a simply-typed, call-by-value (CBV) language with first-class continuations, the usual CBV fixpoint operator can be defined in terms of a simple, infinitely-looping iteration primitive. We first consider a natural but flawed definition, based on exceptions and iterative deepening of finite unfoldings, and point out some of its shortcomings. Then we present the proper construction using full first-class continuations, with both an informal derivation and a proof that the behavior of the defined operator faithfully mimics a built-in recursion primitive. In fact, given an additional uniformity assumption, the construction is a two-sided inverse of the usual definition of iteration from recursion. Continuing, we show that the CBV looping primitive is in fact the direct-style equivalent of a continuation-passing-style fixpoint, and that this correspondence extends all the way to traditional definitions of these operators in terms of reflexive types.An earlier version of this work appeared inProceedings of the 1992 ACM SIGPLAN Workshop on Continuations.Supported in part by NSF Grant CCR-8922109 and in part by the Avionics Lab, Wright Research and Development Center, Aeronautical Systems Division (AFSC), U.S. Air Force, Wright-Patterson AFB, OH 45433-6543 under Contract F33615-90-C-1465, ARPA Order No. 7597. The views and conclusions contained in this document are those of the author and should not be interpreted as representing the official policies, either expressed or implied, of the U.S. Government. 相似文献
46.
Stefan Kiefer Andrzej S. Murawski Joël Ouaknine Björn Wachter James Worrell 《Formal Methods in System Design》2013,43(2):285-312
We present a detailed account of a translation from probabilistic call-by-value programs with procedures to Rabin’s probabilistic automata. The translation is fully abstract in that programs exhibit the same computational behaviour if and only if the corresponding automata are language-equivalent. Since probabilistic language equivalence is decidable, we can apply the translation to analyse the behaviour of probabilistic programs and protocols. We illustrate our approach on a number of case studies. 相似文献
47.
Michał Chojnacki Stanisław Jóźwiak Krzysztof Karczewski Zbigniew Bojar 《Intermetallics》2011,19(10):1555-1562
An attempt to modify sintering of iron and aluminium elemental powders with use of small additions of Mg and MgH2 was presented in this paper. The kinetics of such modified sintering was investigated using DSC technique, XRD analysis and SEM observations. Significant changes in the mechanism of exothermal formation reaction of Fe–Al intermetallic phases in compositions doped with magnesium and its hydride was observed. Initiation temperature of Self-propagating High-temperature Synthesis (SHS) reaction was pronouncedly shifted to lower value as compared with undoped composition. Influence of additions on the SHS reaction kinetics parameters was also calculated with use of the JMA model and changes of the Avrami exponent value of specific phase formation was noticed. Positive effect of MgH2 addition on partial homogeneity of final product was also studied. 相似文献
48.
Stephan van Reenen Piotr Matyba Andrzej Dzwilewski René A. J. Janssen Ludvig Edman Martijn Kemerink 《Advanced functional materials》2011,21(10):1795-1802
Incorporation of ions in the active layer of organic semiconductor devices may lead to attractive device properties like enhanced injection and improved carrier transport. In this paper, we investigate the effect of the salt concentration on the operation of light‐emitting electrochemical cells, using experiments and numerical calculations. The current density and light emission are shown to increase linearly with increasing ion concentration over a wide range of concentrations. The increasing current is accompanied by an ion redistribution, leading to a narrowing of the recombination zone. Hence, in absence of detrimental side reactions and doping‐related luminescence quenching, the ion concentration should be as high as possible. 相似文献
49.
Marcin Słoma Małgorzata Jakubowska Andrzej Kolek Krzysztof Mleczko Piotr Ptak Adam Witold Stadler Zbigniew Zawiślak Anna Młożniak 《Journal of Materials Science: Materials in Electronics》2011,22(9):1321-1329
This paper presents the results of authors investigations on elaboration of a new thick film composition filled with carbon nanotubes (CNTs). The polymer composition consists of polymer vehicle, which is the solution of organic resin in certain combination of solvents, and functional phase—carbon nanotubes well dispersed in the vehicle. The pastes were applied with screen-printing on several substrates and temperature cured. The properties of obtained layers were characterized. Series of samples were prepared with different amount of CNTs to evaluate electrical properties. Changes in resistance were investigated during periodic mechanical and temperature stresses, realized through cyclical bending and rapid temperature change. Tensometric effect was also investigated. Investigations have proved that polymer composites based on carbon nanotubes exhibit high resilience to stress factors. Resistance change in function of temperature was also investigated to evaluate temperature coefficient of resistance (TCR). All this aspects are important for elastic resistors fabrication in printed electronics microcircuits. Resistance and noise measurements in cryostats have also been involved. 1/f type noise has been observed. Noise intensity, calculated in decade frequency bands, rises significantly with increasing temperature. Activation energies of thermally activated noise sources (TANS) have been revealed using low-frequency noise spectroscopy. Relatively large value of negative TCR has been obtained from resistance versus temperature curve. Calculated dimensionless sensitivity is similar to that observed in cryogenic temperature sensors. However, bulk noise intensity of resistive layer is larger than obtained for lead containing RuO2 based resistive layers. 相似文献
50.
The circular dichroism (CD) spectra in visible range of the 3-nitroaniline (m-NA) single crystal, of its solution in chloroform, and in the KBr pellet were recorded. Neither the molecular (m or Cs) nor the crystal (mm2 or C2v) point groups belong to the chiral groups. The DFT calculation of CD spectrum of the m-NA isolated neutral molecule confirmed its chirality. The red shifted bands in the calculated CD spectrum of m-NA radical anion (charged polaron), as compared with the neutral molecule, resemble better the spectra of solids than that of the solution. It seems that these facts corroborate qualitatively the “hop and turn” model explaining the m-NA optical nonlinearity and electric conductivity proposed in Szostak et al. [M.M. Szostak, H. Chojnacki, E. Staryga, M. D?u?niewski, G. B?k, Chem. Phys. 365 (2009) 44-52]. 相似文献