利用有机硅高沸物制备乳化硅油及脱膜剂

实验主要利用有机硅副产物高沸物生产系列有价值的下游产品乳化硅油及脱膜剂.介绍了实验的基本原理、主要工艺操作步骤、所使用原材料及产品质量标准,此产品在一些工业装置上使用效果较佳,有一定应用价值.     

基于ANSYS Workbench柱塞泵主轴动、静态性能分析

主轴是液压泵的重要零件之一,起着传递扭矩的作用,对液压泵的性能有着重要的影响。运用ANSYS Workbench对某型开式回路斜盘式柱塞变量泵的主轴进行动、静态性能分析,主要对柱塞泵主轴进行静力分析和模态分析,得到相关参数,并对主轴进行了一定的优化。为该类主轴的设计和优化提供一定的参考。     

Relative expression and regulation by short-term fasting of lysophosphatidic acid receptors and autotaxin in white and brown adipose tissue depots

Lysophosphatidic acid (lysoPtdOH) levels have previously been reported to decrease in rodents with short-term fasting. We investigated whether a 16 h fast would change expression of autotaxin, the predominant phospholipase D responsible for adipose-derived lysoPtdOH synthesis, or any of the lysophosphatidic acid receptors (1–6) in four white adipose tissue (WAT) depots and interscapular brown adipose tissue (BAT) in male C57Bl/6J mice fed ad libitum, or fasted for 16 h. Aside from small inductions of Lpar1 in epididymal WAT and Lpar2 in epididymal and inguinal WAT, no significant changes were observed in expression of the Lpar family members, or autotaxin in perirenal, retroperitoneal, epididymal, or inguinal WAT or BAT with fasting. Comparison of the relative expression of Lpar1-6 in various depots showed that Lpar6 was the predominant Lpar in both WAT and BAT, and suggests that further work on the adipose-specific role of Lpar6 is warranted.     

Where Are We with RPE Replacement Therapy? A Translational Review from the Ophthalmologist Perspective

The retinal pigmented epithelium (RPE) plays a pivotal role in retinal homeostasis. It is therefore an interesting target to fill the unmet medical need of different retinal diseases, including age-related macular degeneration and Stargardt disease. RPE replacement therapy may use different cellular sources: induced pluripotent stem cells or embryonic stem cells. Cells can be transferred as suspension on a patch with different surgical approaches. Results are promising although based on very limited samples. In this review, we summarize the current progress of RPE replacement and provide a comparative assessment of different published approaches which may become standard of care in the future.     

Novel Putative Transposable Element Associated with the Subtype E5 Botulinum Toxin Gene Cluster of Neurotoxigenic Clostridium butyricum Type E Strains from China

Previously, a whole-genome comparison of three Clostridium butyricum type E strains from Italy and the United States with different C. botulinum type E strains indicated that the bont/e gene might be transferred between the two clostridia species through transposition. However, transposable elements (TEs) have never been identified close to the bont/e gene. Herein, we report the whole genome sequences for four neurotoxigenic C. butyricum type E strains that originated in China. An analysis of the obtained genome sequences revealed the presence of a novel putative TE upstream of the bont/e gene in the genome of all four strains. Two strains of environmental origin possessed an additional copy of the putative TE in their megaplasmid. Similar putative TEs were found in the megaplasmids and, less frequently, in the chromosomes of several C. butyricum strains, of which two were neurotoxigenic C. butyricum type E strains, and in the chromosome of a single C. botulinum type E strain. We speculate that the putative TE might potentially transpose the bont/e gene at the intracellular and inter-cellular levels. However, the occasional TE occurrence in the clostridia genomes might reflect rare transposition events.     

钨含量及固溶温度对022Cr25Ni7Mo3.5WCuN钢耐腐蚀性能的影响

研究了钨含量及固溶温度对超级双相不锈钢022Cr25Ni7Mo3.5WCuN耐点腐蚀性能的影响。通过化学浸泡失重法和电化学极化曲线法,测试了超级双相不锈钢022Cr25Ni7Mo3.5WCuN耐点腐蚀性能,并运用Thermo Calc热力学计算辅助分析。结果表明,固溶温度对超级双相不锈钢022Cr25Ni7Mo3.5WCuN耐点腐蚀性能影响效果显著,在1 100 ℃时,022Cr25Ni7Mo3.5WCuN 的耐腐蚀性能达到最佳;在理想的固溶条件下,钨元素有助于钝化膜的形成,钨含量的增加使得022Cr25Ni7Mo3.5WCuN的耐腐蚀性能增强,在钨质量分数为1.5%时,022Cr25Ni7Mo3.5WCuN获得最佳耐腐蚀性能,若钨含量继续增加,打破了α和γ两相的平衡,则耐蚀性能降低。     

一种X煤在首钢的应用实践

针对当前优质炼焦煤资源越来越少,而高炉生产对焦炭质量指标要求越来越高的情况下,对具有低灰、高硫特点的X煤进行了系统的炼焦试验研究。结果发现,在炼焦生产中合理配加5%～8%的X煤不会造成焦炭硫分升高的不利影响,焦炭灰分下降明显,强度保持稳定。该研究成果成功应用于首钢炼焦生产,焦炭各项指标均达标,这不仅扩大了炼焦煤的使用范围,而且在资源使用方面为公司焦炭灰分的降低提供了支持。     

Basic Oxygen Furnace: Assessment of Recent Physicochemical Models

Metallurgical and Materials Transactions B - Modeling of the basic oxygen furnace (BOF) process, both for online monitoring and fundamental research, has gained importance in steelmaking industry...     

强化石油企业财务管理的对策探讨

议论石油企业经济管理上存在的不足,对加强管理的措施提出了建设性建议.     

The Role of Testosterone in the Elderly: What Do We Know?

Testosterone is the most important hormone in male health. Aging is characterized by testosterone deficiency due to decreasing testosterone levels associated with low testicular production, genetic factors, adiposity, and illness. Low testosterone levels in men are associated with sexual dysfunction (low sexual desire, erectile dysfunction), reduced skeletal muscle mass and strength, decreased bone mineral density, increased cardiovascular risk and alterations of the glycometabolic profile. Testosterone replacement therapy (TRT) shows several therapeutic effects while maintaining a good safety profile in hypogonadal men. TRT restores normal levels of serum testosterone in men, increasing libido and energy level and producing beneficial effects on bone density, strength and muscle as well as yielding cardioprotective effects. Nevertheless, TRT could be contraindicated in men with untreated prostate cancer, although poor findings are reported in the literature. In addition, different potential side effects, such as polycythemia, cardiac events and obstructive sleep apnea, should be monitored. The aim of our review is to provide an updated background regarding the pros and cons of TRT, evaluating its role and its clinical applicability in different domains.