Assessing degradation rates of chlorinated ethylenes in column experiments with commercial iron materials used in permeable reactive barriers

Multiple column experiments were performed using two commercial iron materials to evaluate the necessity and usefulness of preliminary investigations in permeable reactive barrier (PRB) design for chlorinated organics. Experiments were performed with contaminated groundwater and involved fresh iron granules or altered iron material excavated from PRBs. The determination of first-order rate coefficients by global nonlinear least-squares fittings indicated a variability in rate coefficients on 1 or 2 orders of magnitude. Geometric mean values of surface area normalized rate coefficients (in 10(-5) L m(-2) h(-1)) for fresh gray cast iron and iron sponge, respectively, are: tetrachloroethene (4.5, 2.6), trichloroethene (8.1, 3.3), cis-1,2-dichloroethene (3.1, 2.9), trans-1,2-dichloroethene (9.5, 5.3), 1,1-dichloroethene (4.0, 4.4), and vinyl chloride (1.6, 6.1). The increasing rate coefficients with decreasing grade of chlorination, which characterize degradation at iron sponge are linearly related to diffusion coefficients in water, suggesting diffusion limitation in the degradation process for this particular material, possibly due to a high inner surface. The variability in rate coefficients seems to be too high to use mean rate coefficients from published studies in the design procedure of PRBs, and variabilities cannot be related to groundwater characteristics, waterflow through the reactive cells, or secondary corrosion reactions.     

Most-probable-number determination of salmonella levels in naturally contaminated raw almonds using two sample preparation methods

Pathogens occurring in particulate foods may be unevenly distributed, which may impact interpretation of most-probable-number (MPN) values. The MPN analysis of Salmonella in naturally contaminated raw almonds was conducted using two sample preparation methods. Raw almond kernels (3,698 samples) and inshell almonds (455 samples) were collected from almond processors throughout California during the 2006 and 2007 harvests, and 100-g samples were enriched for Salmonella. The prevalence of Salmonella on kernels and inshell almonds was 1.6 and 0.9%, respectively, in 2006, and 0.83 and 2.2%, respectively, in 2007. Almond kernel samples from 2006 were further enriched for Salmonella, and levels of the organism were determined for positive samples by three-tube MPN analysis (25 g, 2.5 g, 0.25 g). Almonds were either divided into subsamples prior to blending and enrichment (method A), or samples were blended in enrichment broth prior to preparation of subsamples (method B). Salmonella was not isolated (<1.2 MPN/100 g) upon retesting of 19 of 31 (method A) or 23 of 29 (method B) positive samples. When detected, levels were 1.4 to 15.5 MPN/100 g (average 2.3 MPN/100 g) or 1.4 to 18.3 MPN/100 g (average 2.1 MPN/100 g) using methods A or B, respectively. A total of 23 different Salmonella serovars were identified from the original almond samples. Salmonella Muenchen was the most frequently isolated serovar (15%) from the 53 Salmonella-positive samples, followed by Newport (12%), Enteritidis (10%), and Typhimurium (8%). No correlation was found between presence of Salmonella and E. coli levels, aerobic plate counts, or counts of yeasts or molds.     

Virtual Support Communities and Psychological Well‐Being: The Role of Optimistic and Pessimistic Social Comparison Strategies

Do the beneficial or detrimental effects of CMC activity depend on the specific social comparison strategy individuals use? The present study aimed to answer this question by examining social comparison strategies, different measures of online activity within the community, and psychological well‐being of users of online breast cancer support communities. Results showed that the relationship between online activity (i.e., length of visits and frequency of posts) and psychological well‐being (i.e., breast cancer related concerns and depression) was determined by users' pessimistic social comparison strategy; downward identification influenced especially highly active users. Findings suggest that active CMC users should be careful not to become entrapped by negative social comparison processes.     

Dissecting the performance of YouTube video streaming in mobile networks

Video streaming applications constitute a significant portion of the Internet traffic today, with mobile accounting for more than half of the online video views. The high share of video in the current Internet traffic mix has prompted many studies that examine video streaming through measurements. However, streaming performance depends on many different factors at different layers of the TCP/IP stack. For example, browser selection at the application layer or the choice of protocol in transport layer can have significant impact on the video performance. Furthermore, video performance heavily depends on the underlying network conditions (eg, network and link layers). For mobile networks, the conditions vary significantly, since each operator has a different deployment strategy and configuration. In this paper, we focus on YouTube and carry out a comprehensive study investigating the influence of different factors on streaming performance. Leveraging the Measuring Mobile Broadband Networks in Europe (MONROE) test bed that enables experimentation with 13 different network configurations in four countries, we collect more than 1800 measurement samples in operational mobile networks. With this campaign, our goal is to quantify the impact of parameters from different layers on YouTube's streaming quality of experience (QoE). More specifically, we analyze the role of the browser (eg, Firefox and Chrome), the impact of transport protocol (eg, TCP or QUIC), the influence of network bandwidth, and signal coverage on streaming QoE. Our analysis reveals that all these parameters need to be taken into account jointly for network management practices, in order to ensure a high end‐user experience.     

Technical-economic evaluation of abrasive recycling in the suspension fine jet process chain

Abrasive waterjet generation methods such as the conventional injection jet method and the suspension jet method have a strong influence on properties and costs of the machined products, particularly ones made of difficult-to-machine materials, e.g., ceramics. Since recycling may reduce the needed amount of materials significantly, the same holds true for recycling processes and technologies within the process chains of abrasive waterjet methods. In this paper, a methodology for integrated technical-economic evaluation of processes is presented and applied to the process technology of abrasive recycling in the suspension fine jet process chain aiming to show the technology’s technical as well as economic potential. Research and development regarding such processes and technologies may contribute to gain competitive advantages for companies as they can differentiate from competitors by offering or processing materials with distinctive properties and/or lower prices causing customer’s benefit. Consequently, it is also of great importance for companies applying waterjet cutting methods to know whether and which recycling technologies are promising from both a technical and an economic point of view. Experiments show that a significant share of the input material (abrasive particles) can be reused after recycling. The monetary appraisal reveals that technical potential results in considerably lower costs compared to the suspension jet method without recycling.     

Activity-tracking devices for older adults: comparison and preferences

Universal Access in the Information Society - Research demonstrates that physical activity beneficially influences brain function, quality of life and reduces cardiovascular diseases. Therefore,...     

New Evidence for P-gp-Mediated Export of Amyloid-β Peptides in Molecular,Blood-Brain Barrier and Neuronal Models

Defective clearance mechanisms lead to the accumulation of amyloid-beta (Aβ) peptides in the Alzheimer’s brain. Though predominantly generated in neurons, little is known about how these hydrophobic, aggregation-prone, and tightly membrane-associated peptides exit into the extracellular space where they deposit and propagate neurotoxicity. The ability for P-glycoprotein (P-gp), an ATP-binding cassette (ABC) transporter, to export Aβ across the blood-brain barrier (BBB) has previously been reported. However, controversies surrounding the P-gp–Aβ interaction persist. Here, molecular data affirm that both Aβ₄₀ and Aβ₄₂ peptide isoforms directly interact with and are substrates of P-gp. This was reinforced ex vivo by the inhibition of Aβ₄₂ transport in brain capillaries from P-gp-knockout mice. Moreover, we explored whether P-gp could exert the same role in neurons. Comparison between non-neuronal CHO-APP and human neuroblastoma SK-N-SH cells revealed that P-gp is expressed and active in both cell types. Inhibiting P-gp activity using verapamil and nicardipine impaired Aβ₄₀ and Aβ₄₂ secretion from both cell types, as determined by ELISA. Collectively, these findings implicate P-gp in Aβ export from neurons, as well as across the BBB endothelium, and suggest that restoring or enhancing P-gp function could be a viable therapeutic approach for removing excess Aβ out of the brain in Alzheimer’s disease.