Acute exposure to gas‐supersaturated water does not affect reproductive success of female adult chinook salmon late in maturation

At times, total dissolved gas concentrations in the Columbia and Snake rivers have been elevated due to involuntary spill from high spring runoff and voluntary spill used as a method to pass juvenile salmonids over dams. The goal of this project was to determine if acute exposure to total dissolved gas supersaturation (TDGS) affects the reproductive performance of female chinook salmon late in their maturation. During this study, adult female spring chinook salmon were exposed to mean TDGS levels of 114.1% to 125.5%. We ended exposures at first mortality, or at the appearance of impending death. Based on this criterion, exposures lasted from 10 to 68 h and were inversely related to TDGS. There was no effect of TDGS on pre‐spawning mortality or fecundity when comparing treatment fish to experimental controls or the general hatchery population four to six weeks after exposures. Egg quality, based on egg weight and egg diameter, did not differ between treatment and control fish. Fertilization rate and survival to eyed‐stage was high ( > 94%) for all groups. With the exception of Renibacterium salmoninarum (the causative agent of bacterial kidney disease; BKD), no viral or bacterial fish pathogens were isolated from experimental fish. The prevalence (about 45%) and severity of R. salmoninarum did not differ among the groups or the general hatchery population. We conclude that these acute exposures to moderate levels of gas‐supersaturated water—perhaps similar to that experienced by immigrating adult salmon as they approach and pass a hydropower dam on the Columbia River—did not affect reproductive success of female chinook salmon late in their maturation. These results are most applicable to summer and fall chinook salmon, which migrate in the summer/fall and spawn shortly after reaching their natal streams. Published in 2004 by John Wiley & Sons, Ltd.     

The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications

Increasing evidence links the RAGE (receptor for advanced glycation end products)/DIAPH1 (Diaphanous 1) signaling axis to the pathogenesis of diabetic complications. RAGE is a multi-ligand receptor and through these ligand–receptor interactions, extensive maladaptive effects are exerted on cell types and tissues targeted for dysfunction in hyperglycemia observed in both type 1 and type 2 diabetes. Recent evidence indicates that RAGE ligands, acting as damage-associated molecular patterns molecules, or DAMPs, through RAGE may impact interferon signaling pathways, specifically through upregulation of IRF7 (interferon regulatory factor 7), thereby heralding and evoking pro-inflammatory effects on vulnerable tissues. Although successful targeting of RAGE in the clinical milieu has, to date, not been met with success, recent approaches to target RAGE intracellular signaling may hold promise to fill this critical gap. This review focuses on recent examples of highlights and updates to the pathobiology of RAGE and DIAPH1 in diabetic complications.     

一起副溶血性弧菌食物中毒分离株的特征分析

目的 分析2017年广州市一起副溶血性弧菌食物中毒分离株的特征.方法 采用血清型鉴定,药敏实验,毒力基因(tdh、trh、tlh)、toxRS/new基因、orf8基因的聚合酶链式反应(PCR)检测,脉冲场凝胶电泳(PFGE)和多位点序列分型(MLST)进行分析.结果 14株副溶血性弧菌血清型鉴定为O8∶K21,药敏试...     

Using technology in higher education: The influence of gender roles on technology self-efficacy

The present study examines the relationship between technology self-efficacy among university students and gender roles. Previous research has based differences in technology self-efficacy on biological sex and found significant differences. University students were asked to complete a survey dealing with gender roles and technology self-efficacy. The current study shows that gender roles, specifically masculinity, is the source of this difference in technology self-efficacy, and not biological sex alone. Further, masculinity predicts technology self-efficacy above and beyond what can be explained by other contributing factors such as previous computer hassles and perceived structural technology support.     

Bayesian network analysis for the dynamic prediction of early stage entrepreneurial activity index

Entrepreneurship plays a critical role for the development and well-being of society. Illustration of its dynamic relationship with entrepreneurial attitudes and aspirations can provide a guideline for the cause of such activities. However, a time-lagged causal relationship among these concepts has not yet been established. In this study, we examine a dynamic relationship among early stage entrepreneurial attitudes, activities, and aspirations using Bayesian network (BN) analysis. In addition, we propose an early stage entrepreneurial activity index that can predict the percentage of both nascent entrepreneur and new business owner using the variables related to entrepreneurial attitudes of the previous year. This index, in turn, can be used to predict various aspects of entrepreneurial aspiration of the following year. The proposed index turns out to have very high prediction accuracy and is expected to provide effective policies to boost future entrepreneurial activity and aspiration.     

The Visual Resources Association,its role and its future

The Visual Resources Association is an international organization for those involved in image information management. Membership includes image specialists of all types, librarians, museum curators, gallery representatives, system vendors, historians, artists, and those involved in intellectual property. The Association has a publications program, and has been working on several initiatives over the last ten years in the areas of intellectual property, the development of image cataloguing standards, and professional status standards. As the image information profession changes, the Association is moving in new directions to continually serve its membership.     

Student perspectives on mentoring in a science outreach project

Abstract

The focus of this paper is an examination of mentorship relationships developed as a result of six students’ participation in a local community science centre sponsored through an NSERC/CRYSTAL project. Each year, a number of students participate in after‐school activities sponsored by the community science centre. Much of this work involves a one‐to‐one approach, with a middle years or high school student working with a professor partner. The professor acts as a mentor to the student, facilitating learning in a manner not always feasible within a school setting with large class sizes. For some students this research may be the basis of a science fair project; for others if is simply a study based on individual interest. Mentored students were interviewed about the nature of that mentorship, with the goal of describing the experience from the students’ perspective. Questions focused on the student's experience of working with a mentor, including how the mentorship relationship was formed, what the importance of the voluntary nature of mentoring was, what the benefits and challenges of working with a mentor were, how the mentorship relationship affected the level of content knowledge the student gained, and what effect the mentoring relationship had on the student's continuing interest in science. The mentorship program offers students the opportunity to work within a developing community of practice.     

Effects of ethanol,formaldehyde, and gentle heat fixation in confocal resonance Raman microscopy of purple nonsulfur bacteria

Resonance Raman microscopy is well suited to examine living bacterial samples without further preparation. Therefore, comparatively little thought has been given to its compatibility with common fixation methods. However, fixation of cell samples is a very important tool in the microbiological sciences, allowing the preservation of samples in a specific condition for further examination, future measurements, transport, or later reference. We examined the effects of three common fixatives—ethanol, formaldehyde solution, and gentle heat—on the resonant Raman spectrum of three generic bacteria species, Rhodobacter sphaeroides DSM 158^T, Rhodopseudomonas palustris DSM 123^T, and Rhodospirillum rubrum DSM 467^T, holding carotenoid‐ and heme‐chromophores in confocal Raman microscopy. In addition, we analyzed the effect of poly‐L ‐lysine coating of microscope slides, widely used for mounting biological and medical samples, on subsequent confocal Raman measurements of native and fixed samples. The results indicate that ethanol is preferable to formaldehyde as fixative if applied for less than 24 h, whereas heat fixation has a strong, detrimental effect on the resonant Raman spectrum of bacteria. Formaldehyde fixation excels at fixation times above 24 h, but causes an overall reduction in signal intensity. Poly‐L ‐lysine coating has no discernable effect on the Raman spectra of samples fixed with ethanol or heat, but it further decreases the signal intensity, especially at higher wavenumbers, in the spectra of samples fixed with formaldehyde. Microsc. Res. Tech. 74:177–183, 2011. © 2010 Wiley‐Liss, Inc.     

Norman Garmezy (1918–2009).

Norman Garmezy, a pioneer in research on risk and resilience, died in Nashville, Tennessee, on November 21, 2009, at the age of 91. He was a legendary mentor as well as an eminent scientist in clinical psychology. Norm was born on June 18, 1918, in New York City and grew up in the Bronx in a Jewish neighborhood where educational attainment was highly valued. The scientific study of resilience as conceived by Norman Garmezy, his peers, and students has transformed the science and practice of multiple disciplines, from the molecular level to the global ecosystem, infusing a strength-based and recovery-oriented approach into psychology, education, social work, and psychiatry. Current research on resilience ranges from studies of plasticity in brain development to effective planning for resilience in the context of disaster. Norm’s influential ideas and research earned him international acclaim and many honors for lifetime achievements in science. Throughout his career, Norm held many leadership roles. Throughout his life, Norm spoke with great love about his wife of 63 years, Edie Garmezy (who died just months before him in 2009), and their children. In addition to his work and his family, Norm had three abiding passions—theater, movies, and politics. During the last two decades of his life, Norm and those who loved him endured his long decline from Alzheimer’s, which slowly stole his brilliant mind and hilarious sense of humor. Nonetheless, the incredible spirit and humanity of this giant scholar continued to shine through this terrible disease. To the end of his life, Norm’s face would light up with a smile as he greeted the people he loved, and he would often exclaim, “Wonderful!” Norman Garmezy was a remarkable person and scholar who left an extraordinary legacy of love and work to inspire future generations in their efforts to understand and promote the human capacity for competence and resilience. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cognition-based and affect-based trust as mediators of leader behavior influences on team performance.

We develop a model in which cognitive and affective trust in the leader mediate the relationship between leader behavior and team psychological states that, in turn, drive team performance. The model is tested on a sample of 191 financial services teams in Hong Kong and the U.S. Servant leadership influenced team performance through affect-based trust and team psychological safety. Transformational leadership influenced team performance indirectly through cognition-based trust. Cognition-based trust directly influenced team potency and indirectly (through affect-based trust) influenced team psychological safety. The effects of leader behavior on team performance were fully mediated through the trust in leader variables and the team psychological states. Servant leadership explained an additional 10% of the variance in team performance beyond the effect of transformational leadership. We discuss implications of these results for research on the relationship between leader behavior and team performance, and for efforts to enhance leader development by combining knowledge from different leadership theories. (PsycINFO Database Record (c) 2011 APA, all rights reserved)