Interaction of Langmuir–Blodgett and spin-coated films of μ-carbido-bridged ironphthalocyanine with NO2: Optical and conductimetric behaviour

The present study investigates the interaction of NO₂ gas and μ-carbido-bridged iron phthalocyanine (PcFeCFePc) films obtained by Langmuir–Blodgett (LB) and spin-coating (SC) techniques. The phthalocyanine bridged dimer under study belongs to the polynuclear unsubstituted phthalocyanines class and presents poor solubility: in contrast the corresponding N-base bis-adducts are soluble enough in organic solvents to be deposited by Langmuir–Blodgett and spin-coating techniques. The reaction with NO₂ is monitored by visible spectra variation that shows identical behaviour for both kinds of films, indicating that the chemical reaction between the gas and the films is independent of the deposition method. The electrical conductivity change as a function of time with NO₂ is instead dissimilar: for spin-coated films it shows a behaviour already observed for sandwich-type phthalocyanine whereas for LB films it resembles that of monomeric phthalocyanine. Such a response implies that the charges (holes) generated in the oxidation/reduction process are carried differently through the material, and we attempt to explain this behaviour taking into account the two different structural and morphological features induced by the two techniques.     

Correcting for the influence of frozen lakes in satellite microwave radiometer observations through application of a microwave emission model

The spatial resolution of passive microwave observations from space is of the order of tens of kilometers with currently available instruments, such as the Special Sensor Microwave/Imager (SSM/I) and Advanced Microwave Scanning Radiometer (AMSR-E). The large field of view of these instruments dictates that the observed brightness temperature can originate from heterogeneous land cover, with different vegetation and surface properties.In this study, we assess the influence of freshwater lakes on the observed brightness temperature of AMSR-E in winter conditions. The study focuses on the geographic region of Finland, where lakes account for 10% of the total terrestrial area. We present a method to mitigate for the influence of lakes through forward modeling of snow covered lakes, as a part of a microwave emission simulation scheme of space-borne observations. We apply a forward model to predict brightness temperatures of snow covered sceneries over several winter seasons, using available data on snow cover, vegetation and lake ice cover to set the forward model input parameters. Comparison of model estimates with space-borne observations shows that the modeling accuracy improves in the majority of examined cases when lakes are accounted for, with respect to the case where lakes are not included in the simulation. Moreover, we present a method for applying the correction to the retrieval of Snow Water Equivalent (SWE) in lake-rich areas, using a numerical inversion method of the forward model. In a comparison to available independent validation data on SWE, also the retrieval accuracy is seen to improve when applying the influence of snow covered lakes in the emission model.     

Object query optimization through detecting independent subqueries

The problem of query optimization in object-oriented databases is addressed. We follow the Stack-Based Approach to query languages, which employs the naming-scoping-binding paradigm of programming languages rather than traditional database concepts such as relational/object algebras or calculi. The classical environment stack is a semantic basis for definitions of object query operators, such as selection, projection/navigation, dependent join, and quantifiers. We describe a general object data model and define a formalized OQL-like query language SBQL. Optimization by rewriting concerns queries containing so-called independent subqueries. It consists in detecting them and then factoring outside loops implied by query operators. The idea is based on the formal static analysis of scoping rules and binding names occurring in a query. It is more general than the classical pushing selections/projections before joins.     

Visualization of myocardial perfusion derived from coronary anatomy

Visually assessing the effect of the coronary artery anatomy on the perfusion of the heart muscle in patients with coronary artery disease remains a challenging task. We explore the feasibility of visualizing this effect on perfusion using a numerical approach. We perform a computational simulation of the way blood is perfused throughout the myocardium purely based on information from a three-dimensional anatomical tomographic scan. The results are subsequently visualized using both three-dimensional visualizations and bull's eye plots, partially inspired by approaches currently common in medical practice. Our approach results in a comprehensive visualization of the coronary anatomy that compares well to visualizations commonly used for other scanning technologies. We demonstrate techniques giving detailed insight in blood supply, coronary territories and feeding coronary arteries of a selected region. We demonstrate the advantages of our approach through visualizations that show information which commonly cannot be directly observed in scanning data, such as a separate visualization of the supply from each coronary artery. We thus show that the results of a computational simulation can be effectively visualized and facilitate visually correlating these results to for example perfusion data.     

Human pathogenic streptococcal proteomics and vaccine development

Gram-positive streptococci are non-motile, chain-forming bacteria commonly found in the normal oral and bowel flora of warm-blooded animals. Over the past decade, a proteomic approach combining 2-DE and MS has been used to systematically map the cellular, surface-associated and secreted proteins of human pathogenic streptococcal species. The public availability of complete streptococcal genomic sequences and the amalgamation of proteomic, genomic and bioinformatic technologies have recently facilitated the identification of novel streptococcal vaccine candidate antigens and therapeutic agents. The objective of this review is to examine the constituents of the streptococcal cell wall and secreted proteome, the mechanisms of transport of surface and secreted proteins, and describe the current methodologies employed for the identification of novel surface-displayed proteins and potential vaccine antigens.     

The cell probe complexity of succinct data structures

We consider time-space tradeoffs for static data structure problems in the cell probe model with word size 1 (the bit probe model). In this model, the goal is to represent n$n$-bit data with s=n+r$s=n+r$ bits such that queries (of a certain type) about the data can be answered by reading at most t$t$ bits of the representation. Ideally, we would like to keep both s$s$ and t$t$ small, but there are tradeoffs between the values of s$s$ and t$t$ that limit the possibilities of keeping both parameters small.     

Segmentation of microscope images of living cells

This paper describes a segmentation method combining a texture based technique with a contour based method. The technique is designed to enable the study of cell behaviour over time by segmenting brightfield microscope image sequences. The technique was tested on artificial images, based on images of living cells and on real sequences acquired from microscope observations of neutrophils and lymphocytes as well as on a sequence of MRI images. The results of the segmentation are compared with the results of the watershed and snake segmentation methods. The results show that the method is both effective and practical.

From Water Poverty to Water Prosperity—A More Participatory Approach to Studying Local Water Resources Management

The Water Poverty Index (WPI), a tool designed for integrated analysis of water issues, was set-up in a community in Madhya Pradesh, India through a transparent and participatory process. Though the aim of the WPI is to primarily use existing statistical data, quantitative information from census and local records was combined with qualitative data from community interviews and participatory exercises. The inclusion of community chosen indicators and the adjustment of values so that higher numbers represent water prosperity rather than water poverty, led to the Water Prosperity Index (WPI⁺). The WPI?⁺?score was contrasted with the WPI at community level. It was also calculated for two community areas with different caste and socio-economic characteristics and weighted separately according to water issues prioritized by men and women. The WPI?⁺?revealed a great difference in water access between the two areas and in prioritized issues between men and women illustrating the importance of appropriate spatial representation and gender sensitive assessments for revealing important disparities. Results also showed that highly aggregated data hide these differences making it more difficult to target the most vulnerable groups when planning measures to increase equitable water allocation. While quantitative data reveal an important perspective of the water situation, qualitative data about adequacy of resources, services or institutions, improve understanding of which issues to prioritize. A valid and useful community water index must be based on representative participation, transparency and local influence on the methodology and subsequent results.     

Information systems for enhancing social experience in a conference context: A sensor based approach

We combine Auto Identification and Web technologies in an extensible on-site event support system for enhancing experience of conference organizers as well as participants. Our system enables users to authenticate themselves using RFID badges and to access interactive, Web-based services via a touchscreen PC. The developed services aim at supporting social interactions of participants, and thus validate the promising usage directions of the combination of offline social networks and the online social Web. The main hypothesis of our work is that: ??A sensor based information system can truly enhance social conference experience.?? Technically, we have investigated employment of Web 2.0 technologies in social, sensor and mobile technologies enabled systems at conferences and events. This article gives an overview of the overall system and its evaluation via a user survey and usage log data collected during the Extended Semantic Web Conference (ESWC) 2010 and similar international conferences, altogether with several hundred participants.