Risk evaluations for the courts: Is service quality a function of specialization?

Psychologists are often asked to testify in court. However, concerns have been expressed in both the legal and psychological literatures about the quality of these services. This article presents survey results comparing the practice patterns of generally licensed psychologists with those of specialist forensic diplomates in providing risk evaluations. Results suggest that general clinicians frequently perform these evaluations, but forensic diplomates use more modern risk instruments, are more aware of the scientific literature, and provide the court with more information about the scientific basis of their testimony. The implication of these results for legal professionals, psychologist training, and practice are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Preliminary structural evaluations of the STAR-LM reactor vessel and the support design

In this paper, preliminary structural evaluations of the reactor vessel and support design of the STAR-LM (The Secure, Transportable, Autonomous Reactor – Liquid Metal variant), which is a lead-cooled reactor, are carried out with respect to an elevated temperature design and seismic design. For an elevated temperature design, the structural integrity of a direct coolant contact to the reactor vessel is investigated by using a detail structural analysis and the ASME-NH code rules. From the results of the structural analyses and the integrity evaluations, it was found that the design concept of a direct coolant contact to the reactor vessel cannot satisfy the ASME-NH rules for a given design condition. Therefore, a design modification with regards to the thermal barrier is introduced in the STAR-LM design. For a seismic design, detailed seismic time history response analyses for a reactor vessel with a consideration of a fluid–structure interaction are carried out for both a top support type and a bottom support type. And from the results of the hydrodynamic pressure responses, an investigation of the minimum thickness design of the reactor vessel is tentatively carried out by using the ASME design rules.     

A Dual-Fed, Self-Diplexing PIFA and RF Front-End

A dual-fed, self-diplexing planar inverted F antenna and an associated RF front-end are described. It is shown that co-design of the antenna and front-end can be used to double the operational bandwidth, without significant size or performance penalties. Indeed, the use of two feeds allows the antenna to be self-diplexing, which results in improved overall efficiency     

Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation

For oxygenation of polyenoic fatty acids by 12- and 15-lipoxygenases the methyl terminus of the substrate constitutes the signal for the initial hydrogen abstraction. In contrast, for 5-lipoxygenases an inverse head to tail substrate orientation has been proposed. However, recent structure-based sequence alignments suggested a conserved uniform substrate orientation for 5S- and 15S-lipoxygenation. Oxygenation of 15S-HETE derivatives by various wild-type and mutant lipoxygenases was investigated, and the evidence proved an inverse substrate orientation: (i) Substrate affinity and Vmax of 15S-HETE oxygenation by arachidonic acid 15-lipoxygenases are >1 order of magnitude lower than the corresponding data for polyenoic fatty acids. 5S,15S- and 14R, 15S-DiH(P)ETE were identified as major reaction products. (ii) Methylation of the carboxylate group of 15S-HETE augmented the reaction rate and shifted the reaction specificity strongly toward 5S-lipoxygenation. In contrast, methyl arachidonate was less effectively oxygenated than the free acid. Methylation of 15S-HETrE(8,11,14), which lacks the C5-C6 double bond, was without major impact on the oxygenation rate and on the product specificity. (iii) Introduction of a bulky glycerol moiety at the carboxylic group of 15S-HETE reversed the kinetic effects of methylation and led to a 14R-oxygenation of the substrate. (iv) When the product pattern of 15S-HETE oxygenation by the recombinant wild-type rabbit 15-lipoxygenase was compared with that formed by the Arg403Leu mutant, 5S- and 8S-lipoxygenations were augmented and 14R, 15S-DiH(P)ETE formation was impaired. (v) Phe353Leu or Ile418Ala mutation of the same enzyme, which favored 12S-HETE formation from arachidonic acid, strongly augmented 8S-lipoxygenation of 15S-HETE methyl ester. These kinetic data and the alterations in the product specificity are consistent with the concept of an inverse head to tail substrate orientation during the oxygenation of 15S-HETE methyl ester and/or of free 15S-HETE by 15-LOXs. For 5S- and 8S-lipoxygenation, 15-HETE may slide into the substrate binding pocket with its carboxy terminus approaching the doubly allylic methylenes C-7 or C-10 to the non-heme iron.     

Influence of preliminary cyclic plastic deformation on crack resistance

The influence of preliminary (before crack origin) cyclic plastic deformation by tension-compression (R = _min/_max = –1 on the brittle fracture resistance of 15Kh2MFA heat resistant steel in two conditions was investigated. The preliminary loading was done at 293 K and the fracture at 123 and 293 K. It was established that in the case of relatively short preliminary deformation the change in static fracture toughness is caused by a change in yield strength as the result of the Bauschinger effect. However, with an increase in cyclic deformation the total irreversibly dispersed specific energy of inelastic deformation and the structural changes in the material are the determining factor. A physically based method is proposed for prediction of the influence of preliminary cyclic plastic deformation on the brittle fracture resistance of cyclically softening steels.Institute of Problems of Strength of the Academy of Sciences of the Ukrainian SSR, Kiev. Leningrad. Translated from Problemy Prochnosti, No. 11, pp. 14–20, November, 1989.     

Synthesis and characterization of phenolic and amino resins based on α, β-unsaturated aldehydes

Phenolic and amino resins on the basis of α,β-unsaturated aldehydes were synthesized in bulk or solution. Catalysts were HCl, H₃PO₄, or formic acid, and in some cases NaOH. The course of the reactions was followed by GPC and NMR while the structure of the reaction products was determined by one- and two-dimensional NMR. The course of the reactions is influenced by experimental conditions: the type of monomers, their molar ratio, the type and quantity of the catalyst, the reaction time and temperature, and the reaction medium. At the beginning of the reaction the addition of a nucleophile to an aldehyde takes place through parallel 1,2-addition to and 1,4-addition to group. Oligomers with ? OH, , and ? CHO functional groups are able to add new monomer units or to react mutually to form higher molecular weight addition and condensation products. The overall rate constants for the beginning of the reactions were between 10^?3 L/mol s for the high reactive mixtures and 10^?7 L/mol s for the less reactive mixtures. The resins were cured by heating at temperatures above 135°C with the addition of hexamethylenetetramine.     

New generation of boiling-water-reactor nuclear power plants of increased safety

Scientific-Research Construction Institute of Power Engineering. Russian Scientific Center Kurchatov Institute. Special Design Office of Industrial Organization Izhorskii Plant. All-Union Scientific-Research and Design Institute of Power Engineering Scientific-Industrial Organization. Translated from Atomnaya Énergiya, Vol. 73, No. 1, pp. 13–19, July, 1992.     

Continuous-time norm-constrained Kalman filtering

This paper considers continuous-time state estimation when part of the state estimate or the entire state estimate is norm-constrained. In the former case continuous-time state estimation is considered by posing a constrained optimization problem. The optimization problem can be broken up into two separate optimization problems, one which solves for the optimal observer gain associated with the unconstrained state estimates, while the other solves for the optimal observer gain associated with the constrained state estimates. The optimal constrained state estimate is found by projecting the time derivative of an unconstrained estimate onto the tangent space associated with the norm constraint. The special case where the entire state estimate is norm-constrained is briefly discussed. The utility of the filtering results developed are highlighted through a spacecraft attitude estimation example. Numerical simulation results are included.     

Inhibition of hepatic cholesterol biosynthesis by chloroquine

Chloroquine is shown to be a potent inhibitor of cholesterol biosynthesis by isolated rat hepatocytes. Half-maximal inhibition of cholesterogenesis occurs at ca. 10μM chloroquine. Chloroquine does not affect fatty acid synthesis by isolated hepatocytes. This suggests that chloroquine acts on the cholesterol biosynthetic pathway beyond the cytosolic acetyl-CoA branchpoint of cholesterol and fatty acid synthesis.