Separation of selective organic acids from wastewater through a polyol supported liquid membrane

Pesticide toxicity databases usually include data on pure chemicals (active ingredients). Technical pesticides formulations, however, are mixtures with adjuvants as applied to fields/crops. Two formulations of the same pesticide can differ in their environmental fate and their toxicity. This work presents the evaluation of the toxicity of the dinitroaniline herbicide, pendimethalin by simultaneous analysis of its respiration rate and generation of a membrane potential (Δ Ψ) in rat liver mitochondria. Chromatography grade pendimethalin (8.2·10^?5 ‐ 5.47·10^?4 M or 23 – 154 ppm) caused lower enhancement of the mitochondrial respiration and decrease of the Δ Ψ than technical grade pendimethalin (Stomp), i.e. the mixture of pure ingredient and adjuvant(s). These effects are comparable to those of 2,4‐dinitrophenol. Pure and technical grade pendimethalin acts as an uncoupler of oxidative phosphorylation in mitochondria (enhances respiration and diminishes Δ Ψ). These data conflict with the statement, presented in the US EPA manual Recognition and Management of Pesticides Poisonings, that pendimethalin does not act as an uncoupler of oxidative phosphorylation.     

Experimental Investigation of the Properties of Lime-Based Plaster-Containing PCM for Enhancing the Heat-Storage Capacity of Building Envelopes

Experimental analysis of a wide range of properties of a lightweight plaster which should enhance the heat-storage capacity of building envelopes is presented. The basic physical characteristics, namely, the bulk density, matrix density, total open porosity, and pore-size distribution are measured at first. Then, the compressive strength is determined for an assessment of mechanical performance of the plaster. The thermal conductivity and thermal diffusivity are studied using an impulse technique. Differential scanning calorimetry measurements are performed as well, in order to identify the temperature range and latent heat of the phase change and to determine the specific heat capacity as a function of temperature. Durability properties are assessed using the measurement of the water absorption coefficient and sorption and desorption isotherms. The experimental results indicate a good capability of the designed plaster to moderate effectively the interior climate of buildings.     

Brachistochronic motion of a nonholonomic rheonomic mechanical system

The brachistochrone problem of the rheonomic mechanical system whose motion is subject to nonholonomic constraints is solved with nonlinear differential equations of motion. Apart from control forces, the system is influenced by the action of other known potential and nonpotential forces as well. The problem of optimal control is solved by applying Pontryagin’s Maximum Principle and the singular optimal control theory. This procedure results in the two-point boundary value problem for the system of ordinary nonlinear differential equations of the first order, with a corresponding number of initial and end conditions. This paper determines the control forces that are realized by imposing on the system a corresponding number of independent ideal holonomic constraints, without the action of active control forces. These constraints must be in accordance with the previously determined brachistochronic motion. The method is illustrated with a single complex example that represents the first known concrete demonstration of brachistochronic motion of the nonholonomic rheonomic mechanical system.     

Thermal stability of magnetron sputtered Si–B–C–N materials at temperatures up to 1700 °C

Thermal stability of deposited Si–B–C–N materials (film fragments or powders without a substrate) in inert gases (He and Ar) up to 1700 °C was investigated using differential scanning calorimetry, high-resolution thermogravimetry and X-ray diffraction measurements. Amorphous Si–B–C–N films were fabricated by dc magnetron co-sputtering of a single B₄C–Si target in two nitrogen–argon gas mixtures (50% N₂ + 50% Ar or 25% N₂ + 75% Ar). It was found that the deposited Si–B–C–N materials can be more stable at high temperatures in the inert atmosphere than the usually used substrates (e.g. SiC or BN). The materials with the compositions (in at.%) Si_32–33B₁₀C₂N_50–51, for which N/(Si + B + C) = 1.1–1.2, retained their amorphous structure up to 1600 °C without any structural transformations and detectable mass changes.     

Digital spectrometer for coincidence measurement of Doppler broadening of positron annihilation radiation

High-resolution digital coincidence Doppler broadening spectrometer equipped with two high-purity Ge detectors and two-channel 12-bit fast digitizer was developed and tested in this work. Two configurations were compared: (i) semi-digital setup which uses active analogue shaping of detector pulses prior to digitization to improve signal-to-noise ratio, and (ii) pure-digital setup which samples detector pulses directly. Software procedure developed for analysis of sampled waveforms, i.e. precise determination of energy of detected photon and rejection of distorted pulses, is described. Performance of digital coincidence spectrometer was compared with traditional analogue setup connected to the same detectors. It was found that digital spectrometer enables to achieve better energy resolution than in traditional analogue setup. Moreover, in digital configuration one has better control over shape of the signal. This allows efficient elimination of undesired distorted or damaged waveforms and to obtain spectrum of better clarity. The superior parameters of new digital coincidence Doppler broadening spectrometer are demonstrated by benchmark measurements of well defined Fe and Al specimens and also by the detection of rare annihilation in flight events.     

Thermometry in Normal Liquid 3He Using a Quartz Tuning Fork Viscometer

We have developed the use of quartz tuning forks for thermometry in normal liquid ³He. We have used a standard 32 kHz tuning fork to measure the viscosity of liquid ³He over a wide temperature range, 6 mK<T<1.8 K, at SVP. For thermometry above 40 mK we used a calibrated ruthenium oxide resistor. At lower temperatures we used vibrating wire thermometry. Our data compare well with previous viscosity measurements, and we give a simple empirical formula which fits the viscosity data over the full temperature range. We discuss how tuning forks can be used as convenient thermometers in this range of temperatures with just a single parameter needed for calibration.     

Synthesis of regional networks for the supply of energy and bioproducts

This article presents a method for the synthesis of regional renewable energy supply chains, based on Mixed-Integer Linear Programming (MILP). This method addresses the challenges presented by biomass resources. The main challenges are the distributive and varied availabilities regarding both location and time. This work also aims to maximise the economically viable utilisation of resources, accounting for the competition between energy and food production. A four-layer supply chain superstructure has been developed, which includes the harvesting, preparation, core processing and distribution of products. This considered system’s boundaries involve a region, which is then divided into zones for optimising conversion operations and transportation flows. An MILP model has been formulated with profit maximisation as the optimisation criterion. The environmental impact is evaluated by the carbon footprint. The sensitivity of the optimal solutions is analysed for different regions’ sizes, transportation costs, pre-processing alternatives and the co-production of food and energy.     

Bioactive glass–ceramic coated titanium implants prepared by electrophoretic deposition

Surface modification of Ti alloys towards an improved osteoinductive behaviour is one of the major challenges in orthopaedic implant technology nowadays. One way to achieve this is by applying a bioactive coating which can increase the rate of osseointegration and chemical bonding of surrounding bone to the implant. In the present work, the production of a bioactive glass–ceramic coating on flat Ti alloys by electrophoretic deposition is demonstrated. The coatings are applied by cathodic deposition from non-aqueous suspensions followed by sintering in vacuum, avoiding uncontrolled oxidation of the Ti substrates. The use of non-aqueous suspensions both allowed to reduce the deposition time and yielded homogeneous coatings with a uniform thickness of 8 μm. Evaluation of the coating adhesion confirmed the good mechanical performance of the coatings with a tensile bond strength of 41.0 ± 11.1 MPa. Additionally, a feasibility study demonstrated the potential of electrophoretic deposition as a coating technique for commercial complex implants.     

Development of a solid self-microemulsifying drug delivery system (SMEDDS) for solubility enhancement of naproxen

Context: Comparative evaluation of liquid and solid self-microemulsifying drug delivery systems (SMEDDS) as promising approaches for solubility enhancement.

Objective: The aim of this work was to develop, characterize, and evaluate a solid SMEDDS prepared via spray-drying of a liquid SMEDDS based on Gelucire® 44/14 to improve the solubility and dissolution rate of naproxen.

Material and methods: Various oils and co-surfactants in combination with Gelucire® 44/14 were evaluated during excipient selection study, solubility testing, and construction of (pseudo)ternary diagrams. The selected system was further evaluated for naproxen solubility, self-microemulsification ability, and in vitro dissolution of naproxen. In addition, its transformation into a solid SMEDDS by spray-drying using maltodextrin as a solid carrier was performed. Scanning electron microscopy (SEM), differential scanning calorimetry (DSC), and X-ray diffraction (XRD) were used to evaluate the physical characteristics of the solid SMEDDS obtained.

Results: The selected formulation of SMEDDS was comprised of Miglyol 812®, Peceol?, Gelucire® 44/14, and Solutol® HS 15. The liquid and solid SMEDDS formed a microemulsion after dilution with comparable average droplet size and exhibited uniform droplet size distribution. In the solid SMEDDS, liquid SMEDDS was adsorbed onto the surface of maltodextrin and formed smooth granular particles with the encapsulated drug predominantly in a dissolved state and partially in an amorphous state. Overall, incorporation of naproxen in SMEDDS, either liquid or solid, resulted in improved solubility and dissolution rate compared to pure naproxen.

Conclusion: This study indicates that a liquid and solid SMEDDS is a strategy for solubility enhancement in the future development of orally delivered dosage forms.