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51.
52.
Krajewski Paul E. Morales Arianna T. 《Journal of Materials Engineering and Performance》2004,13(6):700-709
Quick plastic forming (QPF) was developed as a high-volume, hot blow forming process for automobile components, enabling larger
volume applications than traditional superplastic forming (SPF). One critical aspect of the process is the tribological interaction
between the forming tool and the aluminum blank, as this impacts formability, surface quality, and tool durability. While
QPF has been successfully implemented for automobile components, many opportunities exist for improving the tribological condition
during the process, including the die coating or treatment, the lubricant, and the fundamental understanding of aluminum/iron
adhesion under QPF conditions (450 °C). This work reviews key tribological issues affecting QPF and identifies areas where
additional research is required.
This paper was presented at the International Symposium on Superplasticity and Superplastic Forming, sponsored by the Manufacturing
Critical Sector at the ASM International AeroMat 2004 Conference and Exposition, June 8–9, 2004, in Seattle, WA. The symposium
was organized by Daniel G. Sanders, The Boeing Company. 相似文献
53.
Ivana Barravecchia Chiara De Cesari Olga V. Pyankova Francesca Scebba Marco Carlo Mascherpa Alessandra Vecchione Arianna Tavanti Lorena Tedeschi Debora Angeloni 《Microgravity science and technology》2018,30(3):309-319
Performing cell biology experiments in space imposes the use of hardware that essentially allows fluid exchange in a contained environment. Given the technical and logistical peculiarities, the limited opportunities and the high cost of access to space, a great effort during mission preparation of scientific studies is devoted to preventing loss of the experiment. The European Space Agency (ESA) requires, at the end of the preparation phase, the execution of an Experiment Sequence Test (EST), a dry-run version of the space experiment to check all procedures. At conclusion of the EST of our experiment ‘ENDO’ (ESA ILSRA-2009-1026), we found pitting corrosion of metal parts and biofilm formation within the cell-culture devices. The subsequent chemical (spectral assays), instrumental (OGP SmartScope) and microbiological (MALDI-TOF, 16S rRNA gene sequencing) investigations allowed the identification in contaminated material of Paenibacillus glucanolyticus, a ubiquitous, aerobic, facultative anaerobic, endospore forming, acid-producing, Gram-positive microorganism. A concurrence of P. glucanolyticus contamination and galvanic corrosion determined massive fouling, rust precipitation and damage to cells and cell-culture devices being, to our knowledge, the association between this microbe and corrosion never reported before in literature. As a consequence of the episode a critical procedure of experiment set up, i.e. hardware sterilization, was modified. The ENDO experiment was successfully launched to the International Space Station on September 2nd 2015 and returned to the PI laboratory on September 13th, with all cell culture samples in optimal condition. 相似文献
54.
Renau-Pruñonosa Arianna Morell Ignacio Pulido-Velazquez David 《Water Resources Management》2016,30(13):4823-4837
Water Resources Management - In this paper we will focus on an interesting and complex problem, the analysis of coastal aquifer management alternatives in aquifers affected by seawater intrusion... 相似文献
55.
Giampaolo Ricci Arianna Dondi Tamara Belotti Elena Baldi Stefano Tartarini Roberta Paris Giulia Pagliarani Donatella Serafini‐Fracassini Rita Casadio Arianna Giannetti Massimo Masi 《International Journal of Food Science & Technology》2010,45(7):1517-1523
To evaluate differences in skin prick test response to apple cultivars in patients with apple allergy, 19 patients (10 adults and 9 children) underwent prick‐to‐prick skin prick test with eleven commercial and noncommercial apple cultivars, and evaluation of specific IgE to apple and recombinant apple allergens Mal d 1 and Mal d 3. The results show that different reactions might be evoked in a single patient by different apple cultivars and also separately for the peel and the pulp of a single cultivar. The cultivars were ranked according to their allergenicity level, being Jonathan, Jonagold, Golden Delicious and Fiesta the most allergenic when considering the pulp and Gala, Fiesta and Golden Delicious for the peel. Further investigations are needed to clarify if a single patient can be allergic only to well‐defined apple cultivars and which allergometric tests are necessary to ascertain this. 相似文献
56.
Ranjana Sahai Marco Cecchini Mirko Klingauf Aldo Ferrari Chiara Martino Piero Castrataro Vincenzo Lionetti Arianna Menciassi Fabio Beltram 《Microfluidics and nanofluidics》2011,11(6):763-771
This paper reports the development, modeling, and testing of an original microfluidic chip capable of generating both time-evolving
and spatially varying gradients in standard Petri dishes. It consists of three sets of five independently controlled parallel
channels, and its architecture allows the generation of complex gradient profiles that can be flexibly positioned and dynamically
altered in an open cell-chamber environment. A detailed fabrication protocol for the production of these chips using multilayer
soft lithography is reported. A comprehensive computational model is also presented based on COMSOL Multiphysics software
that includes both diffusion and advection of the fluid as it exits the microchannels. The results of the simulation are successfully
applied to model single-channel experiments. The chip is then tested in multi-channel mode, and its ability to produce complex
spatially varied concentration profiles is demonstrated. The achievement of steady state of the gradient profile in less than
5 min also allows for the dynamic variation of the profile. Finally, we apply the present chip architecture to investigate
the migration of mouse neutrophils in an Interleukin-8 gradient. We report quantitatively on cell migration driven by Interleukin-8
gradient and provide migration speed distribution. 相似文献
57.
58.
Gianni Ciofani Serena Danti Delfo D’Alessandro Stefania Moscato Mario Petrini Arianna Menciassi 《Nanoscale research letters》2010,5(7):1093-1101
In the latest years, innovative nanomaterials have attracted a dramatic and exponentially increasing interest, in particular
for their potential applications in the biomedical field. In this paper, we reported our findings on the cytocompatibility
of barium titanate nanoparticles (BTNPs), an extremely interesting ceramic material. A rational and systematic study of BTNP
cytocompatibility was performed, using a dispersion method based on a non-covalent binding to glycol-chitosan, which demonstrated
the optimal cytocompatibility of this nanomaterial even at high concentration (100 μg/ml). Moreover, we showed that the efficiency
of doxorubicin, a widely used chemotherapy drug, is highly enhanced following the complexation with BTNPs. Our results suggest
that innovative ceramic nanomaterials such as BTNPs can be realistically exploited as alternative cellular nanovectors. 相似文献
59.
60.
Raffaella Crescenzo Francesca Bianco Arianna Mazzoli Antonia Giacco Giovanna Liverini Susanna Iossa 《International journal of molecular sciences》2015,16(5):10674-10685
Aging is associated with a progressive loss of maximal cell functionality, and mitochondria are considered a key factor in aging process, since they determine the ATP availability in the cells. Mitochondrial performance during aging in skeletal muscle is reported to be either decreased or unchanged. This heterogeneity of results could partly be due to the method used to assess mitochondrial performance. In addition, in skeletal muscle the mitochondrial population is heterogeneous, composed of subsarcolemmal and intermyofibrillar mitochondria. Therefore, the purpose of the present review is to summarize the results obtained on the functionality of the above mitochondrial populations during aging, taking into account that the mitochondrial performance depends on organelle number, organelle activity, and energetic efficiency of the mitochondrial machinery in synthesizing ATP from the oxidation of fuels. 相似文献