Effect of process parameters on properties of wet‐spun poly(L,D‐lactide) copolymer multifilament fibers

Poly(L,D ‐lactide) [P(L,D )LA], LL/D ratio 96/4, and poly(L,DL ‐lactide) [P(L,DL )LA], L/DL ratio 70/30, multifilament fibers were prepared by wet‐spinning and the effects of the spin draw ratio and the coagulant on the morphological, thermal, and mechanical properties of the filaments were studied. The hydrolytic degradation of filaments was studied in vitro. The filament diameter and the mechanical properties of filaments were highly dependent on the spin draw ratio, whereas the coagulant had no or minor effect. The filament diameters were in the range of 11–36 μm and the maximum tenacity of 150 MPa was obtained at the spin draw ratio of 7.0 for both copolymers. The copolymer had the main importance on the crystallinity of filaments, but it was also affected by the duration of the coagulation process. The crystallinities of P(L,D )LA 96/4 filaments were in the range of 5–16%, whereas P(L,DL )LA 70/30 filaments were totally amorphous. The degree of crystallinity had effect on the hydrolytic degradation of filaments. The tenacity loss of P(L,D )LA 96/4 filaments was about 10% and that of P(L,DL )LA 70/30 filaments was as high as 50% after 24 weeks in vitro. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009     

Adolescent snus use in Finland in 1981-2003: trend, total sales ban and acquisition

Objective

To study changes in adolescent snus use from 1981 to 2003, the effects of the total snus sales ban (1995) and snus acquisition.

Design

Biennial postal surveys in 1981–2003.

Setting and participants

Entire Finland; 12‐, 14‐, 16‐, and 18‐year‐olds (n  =  73 946; 3105−8390 per year).

Main outcome measures

Snus use (experimental, daily/occasionally), snus acquisition (2001, 2003).

Results

Snus experimentation grew in popularity before the total sales ban in 16‐ and 18‐year‐old boys and after the ban in all age and sex groups. A decrease was seen between 2001 and 2003, except for 18‐year‐old boys. Daily/occasional use mainly followed the same pattern in boys while in girls the daily/occasional use was rare and no significant changes were observed. In 2003, boys experimented with snus more often than girls (12‐year‐olds 1% v 0%, 14‐year‐olds 9% v 4%, 16‐year‐olds 30% v 12%, 18‐year‐olds 44% v 18%). Hardly any girls used snus daily/occasionally, but 1% of 14‐year‐old boys, 7% of 16‐year‐olds, and 9% of 18‐year‐olds did. Of daily/occasional users, 84% acquired snus from friends or acquaintances, 55% from tourist trips to neighbouring countries (Estonia, Sweden), and 7% through sport teams; 24% obtained it from under‐the‐counter sources. For experimenters, the corresponding figures were 79%, 18%, 0.3%, and 5%.

Conclusions

The total sales ban did not stop snus use; instead, the increase continued after the ban. Friends who travel to neighbouring countries act as go‐betweens reselling snus. Snus is used even by the youngest adolescents, thus contributing to the nicotine dependence process.     

In situ production and analysis of Weissella confusa dextran in wheat sourdough

Several lactic acid bacteria belonging to the genera Leuconostoc, Lactobacillus, and Weissella have been introduced to wheat sourdough baking for in situ production of exopolysaccharides. This is considered a novel method for improving the shelf-life, volume and nutritional value of bread without additives. However, in situ production of exopolysaccharides during sourdough fermentation is challenged by simultaneous acidification due to metabolic activities of the bacteria, which may significantly diminish the positive technological impact of exopolysaccharides. In this study, the growth, activity and in situ production of dextran by Weissella confusa VTT E-90392 in wheat sourdoughs were investigated. Furthermore, the influence of dextran-enriched sourdoughs, at the addition level of 43%, on the subsequent bread quality was established. W. confusa efficiently produced dextran from the added sucrose in wheat sourdough without strong acid production. A new specific enzyme-assisted method for in situ analysis of dextran in sourdoughs was developed. With this method, we could for the first time proof significant (11–16 g/kg DW) production of polymeric dextran in sourdoughs. Concomitant formation of shorter isomaltooligosaccharides by W. confusa was also detected. The produced dextran significantly increased the viscosity of the sourdoughs. Application of dextran-enriched sourdoughs in bread baking provided mildly acidic wheat bread with improved volume (up to 10%) and crumb softness (25–40%) during 6 days of storage. Hence, W. confusa is a promising new strain for efficient in situ production of dextrans and isomaltooligosaccharides in sourdoughs without strong acidification.     

Improvement of metal properties by ion implantation

Ion implantation is being investigated as a technique for the beneficial modification of surface-sensitive and life-limiting properties of metals including resistance to wear and fatigue. Ion implantation is a process of accelerating ions to high velocities and directing them into the near-surface regions of materials (e.g. alloys) to produce in essence a different material (alloy) in the near-surface region. Ion implantation can produce a graded alloy from the surface to the unchanged underlying bulk alloys so that both the surface and the bulk alloys can be independently optimized. The implanted layer is typically hundreds to thousands of ångströms deep with implanted atom concentrations of up to fifty atomic per cent or more. The sliding-wear rate between various steel alloys was significantly reduced by implanting one of the surfaces with selected elemental species such as nitrogen, carbon and titanium. Experiments were conducted on a number of materials including stainless steel, too steel, bearing alloys and silicon nitride. The implantation technique has also been reported to increase fatigue lifetimes in low-carbon steel by a factor of 50–100. Experimentation is now being directed towards other materials of major technological interest such as titanium alloys. The effect of ion implantation on (1) the wear and fatigue properties and (2) the microstructural characteristics of implanted materials with selected examples is discussed.     

Development of a portable test device for assessing on-site floor slipperiness: an interim report

The main objective was to design and construct a prototype portable slipmeter with the capability of measuring static, transitional kinetic and steady-state kinetic coefficient of friction properties of on-site floors. The second objective was to evaluate its operation in the laboratory, using a commercial force platform as reference. The prototype was found to be capable of measuring the described frictional characteristics of floor surfaces, using three different test wheels and two modes of operation, impact and non-impact testing. The results anticipate that the slipmeter may prove to be more valid than any traditional measurement technique. The study continues with biomechanical trials and will be completed during the year 2000.     

Pipeline materials modify the effectiveness of disinfectants in drinking water distribution systems

We studied how pipe material can modify the effectiveness of UV- and chlorine disinfection in drinking water and biofilms. This study was done with two pipe materials: copper and composite plastic (polyethylene, PE) in a pilot scale water distribution network. UV-disinfection decreased viable bacterial numbers in the pilot waterworks and outlet water of pipes on average by 79%, but in biofilms its disinfecting effect was minor. Chlorine decreased effectively the microbial numbers in water and biofilms of PE pipes. In outlet water from copper pipes, the effect of chlorination was weaker; microbial numbers increased back to the level before chlorination within a few days. In the biofilms present in the copper pipes, chlorine decreased microbial numbers only in front of the pipeline. One reason for weaker efficiency of chlorine in copper pipes was that its concentration declined more rapidly in the copper pipes than in the PE pipes. These results means that copper pipes may require a higher chlorine dosage than plastic pipes to achieve effective disinfection of the pipes.     

Electrospray Encapsulation of Hydrophilic and Hydrophobic Drugs in Poly(L‐lactic acid) Nanoparticles

An electrospray method is developed for preparation of beclomethasone‐dipropionate‐ and salbutamol‐sulfate‐loaded biodegradable poly(L ‐lactic acid) nanoparticles. Different set‐up parameters for electrospraying are examined on particle size, and preparation conditions are optimized for producing spherical‐drug‐loaded nanoscale particles by controllable processing parameters. Polylactide (PLA)–drug nanoparticles with average diameters of around 200 nm are achieved in a stable cone‐jet mode with a flow rate of 4 µL min^?1, polymer concentration of 1%, and ammonium hydroxide content of 0.05%. Morphology and size of the drug–polymer nanoparticles are analyzed by scanning electron microscopy and transmission electron microscopy. Changes in the crystallinity of the PLA polymer and the model drugs are detected by X‐ray powder diffraction, and the absence of molecular interactions are confirmed by thermal analyses. The results indicate clearly that electrospraying is a potential method for producing polymeric nanoparticles and for encapsulating both hydrophilic and hydrophobic drugs efficiently into the nanoparticles.     

Antenna measurements using a hologram CATR

It becomes increasingly difficult to obtain far-field measurements for large millimetre wave antennas at higher frequencies due to the required large distance between the antennas. A hologram compact antenna test range (CATR) is used to determine the radiation characteristics of a 39 GHz planar antenna in a small facility. The results are compared with those obtained from planar near-field scanning and conventional far-field measurements