Outsourcing der Informationsverarbeitung im Mittelstand: Test eines multitheoretischen Kausalmodells

In this paper determinants of information systems (IS) outsourcing are deduced from transaction cost economic theory, resource-based theory and power theory. They are summarized in a theoretical framework which is tested using a sample of small and medium sized enterprises (SMEs) in Germany. The results show that internal performance and know-how deficits vis-à-vis external service providers are key determinants that explain why different IS functions are outsourced to varying degrees in SMEs. Moreover, the determinants of IS functions were found to partially differ between IS functions. Revised reprint of an article from WIRTSCHAFTSINFORMATIK 43(4)2001:339–350.     

Parsing human skeletons in an operating room

Multiple human pose estimation is an important yet challenging problem. In an operating room (OR) environment, the 3D body poses of surgeons and medical staff can provide important clues for surgical workflow analysis. For that purpose, we propose an algorithm for localizing and recovering body poses of multiple human in an OR environment under a multi-camera setup. Our model builds on 3D Pictorial Structures and 2D body part localization across all camera views, using convolutional neural networks (ConvNets). To evaluate our algorithm, we introduce a dataset captured in a real OR environment. Our dataset is unique, challenging and publicly available with annotated ground truths. Our proposed algorithm yields to promising pose estimation results on this dataset.     

The State of the Art in Topology‐Based Visualization of Unsteady Flow

Vector fields are a common concept for the representation of many different kinds of flow phenomena in science and engineering. Methods based on vector field topology are known for their convenience for visualizing and analysing steady flows, but a counterpart for unsteady flows is still missing. However, a lot of good and relevant work aiming at such a solution is available. We give an overview of previous research leading towards topology‐based and topology‐inspired visualization of unsteady flow, pointing out the different approaches and methodologies involved as well as their relation to each other, taking classical (i.e. steady) vector field topology as our starting point. Particularly, we focus on Lagrangian methods, space–time domain approaches, local methods and stochastic and multifield approaches. Furthermore, we illustrate our review with practical examples for the different approaches.     

Rectangle packing with additional restrictions

We formulate a generalization of the NP-complete rectangle packing problem by parameterizing it in terms of packing density, the ratio of rectangle areas, and the aspect ratio of individual rectangles. Then we show that almost all restrictions of this problem remain NP-complete and identify some cases where the answer to the decision problem can be found in constant time.     

Combining Local and Global Model Checking

The verification process of reactive systems in local model checking [1,7] and in explicit state model checking is[13,15] on-the-fly. Therefore only those states of a system have to be traversed that are necessary to prove a property. In addition, if the property does not hold, than often only a small subset of the state space has to be traversed to produce a counterexample. Global model checking [6,23] and, in particular, symbolic model checking [4,22] can utilize compact representations of the state space, e.g. BDDs [3], to handle much larger designs than what is possible with local and explicit model checking. We present a new model checking algorithm for LTL that combines both approaches. In essence, it is a generalization of the tableau construction of [1] that enables the use of BDDs but still is on-the-fly.     

The impact of cultural differences in offshore outsourcing—Case study results from German–Indian application development projects

Offshore outsourcing to vendors in foreign countries causes unique challenges which need to be understood and managed effectively. This paper explores cultural differences in IS offshoring arrangements involving German client organizations that outsource application development activities to Indian vendors. For this purpose, a research framework is developed based on both theoretical considerations and specific empirical observations from multiple case studies. The goal is to (1) explore the nature of cultural differences in offshore outsourcing arrangements in depth and to (2) analyze the relationship between those cultural differences and offshore outsourcing success. Based on the case findings, implications and practices for the management of offshore development projects are outlined. The results indicate that cultural differences in terms of power distance, IS designer values, and an active versus passive working attitude critically affect several dimensions of relationship quality, thereby influencing offshore outsourcing success. A clear definition of roles and mechanisms, strong leadership, and an active management of culture by adapting to either the client’s or the vendor’s national culture appeared to be effective ways to manage cultural differences.

Bounded Model Checking Using Satisfiability Solving

The phrase model checking refers to algorithms for exploring the state space of a transition system to determine if it obeys a specification of its intended behavior. These algorithms can perform exhaustive verification in a highly automatic manner, and, thus, have attracted much interest in industry. Model checking programs are now being commercially marketed. However, model checking has been held back by the state explosion problem, which is the problem that the number of states in a system grows exponentially in the number of system components. Much research has been devoted to ameliorating this problem.In this tutorial, we first give a brief overview of the history of model checking to date, and then focus on recent techniques that combine model checking with satisfiability solving. These techniques, known as bounded model checking, do a very fast exploration of the state space, and for some types of problems seem to offer large performance improvements over previous approaches. We review experiments with bounded model checking on both public domain and industrial designs, and propose a methodology for applying the technique in industry for invariance checking. We then summarize the pros and cons of this new technology and discuss future research efforts to extend its capabilities.     

Human eye-head co-ordination in natural exploration

During natural behavior humans continuously adjust their gaze by moving head and eyes, yielding rich dynamics of the retinal input. Sensory coding models, however, typically assume visual input as smooth or a sequence of static images interleaved by volitional gaze shifts. Are these assumptions valid during free exploration behavior in natural environments? We used an innovative technique to simultaneously record gaze and head movements in humans, who freely explored various environments (forest, train station, apartment). Most movements occur along the cardinal axes, and the predominance of vertical or horizontal movements depends on the environment. Eye and head movements co-occur more frequently than their individual statistics predicts under an independence assumption. The majority of co-occurring movements point in opposite directions, consistent with a gaze-stabilizing role of eye movements. Nevertheless, a substantial fraction of eye movements point in the same direction as co-occurring head movements. Even under the very most conservative assumptions, saccadic eye movements alone cannot account for these synergistic movements. Hence nonsaccadic eye movements that interact synergistically with head movements to adjust gaze cannot be neglected in natural visual input. Natural retinal input is continuously dynamic, and cannot be faithfully modeled as a mere sequence of static frames with interleaved large saccades.     

A theory of mode of action of azolylalkylquinolines as DNA binding agents using automated flexible ligand docking

Azolylalkylquinolines (AAQs) are a family of quinolines with varying degrees of cytotoxic activity (comparable or moderately superior to adriamycin in some cases) developed in the past decade in our group where their exact mode of action is still unclear. In this study the most probable DNA binding mode of AAQs was investigated employing a novel flexible ligand docking approach by using AutoDock 3.0. Forty-nine AAQs with known experimental inhibitory activity were docked onto d(CGCAAATTTGCG)(2), d(CGATCG)(2) and d(CGCG)(2) oligonucleotides retrieved from the Protein Data Bank (PDB IDs: 102D, 1D12 and 1D32, respectively) as the representatives of the three plausible models of interactions between chemotherapeutic agents and DNA (groove binding, groove binding plus intercalation and bisintercalation, respectively). Good correlation (r(2)=0.64) between calculated binding energies and experimental inhibitory activities was obtained using groove binding plus intercalation model for phenyl-azolylalkylquinoline (PAAQ) series. Our findings show that the most probable mode of action of PAAQs as DNA binding agents is via intercalation of quinolinic moiety between CG base pairs with linker chain and azole moiety binding to the minor groove.