Impact of the solidification path of FeOx–SiO2 slags on the resultant inorganic polymers

Aiming to reduce the carbon dioxide emissions associated with cement production, alternative binders such as inorganic polymers currently receive substantial attention and slags from the non-ferrous metallurgy are promising precursors. However, studies  that correlate their chemistry and crystallinity with the newly formed binder remain limited. In this work, the effect of three different solidification methods on glass formation and reactivity of FeO_x–SiO₂ slags, as well as on the molecular structure of the resultant Fe-rich inorganic polymers, was investigated. The inorganic polymers were synthesized by mixing the slags (approximate molar ratio FeO/SiO₂ = 1.6) with an alkali silicate solution (molar ratios SiO₂/Na₂O = 1.6 and H₂O/Na₂O = 25). Results demonstrated that higher cooling rates promoted higher glass formation and faster reaction kinetics when the slags were activated. ⁵⁷Fe Mössbauer spectroscopy indicated that all the slags consisted predominantly of Fe²⁺ ions with a minor amount of Fe³⁺ ions, regardless of the variability in glass content. The binder phase of all inorganic polymers consisted of iron in both Fe²⁺ and Fe³⁺ states, after 28 days of curing. After pulverizing the inorganic polymer pastes and exposing the powder to air for 28 additional days, the Fe²⁺ state in the binder transformed to Fe³⁺. The compressive strength evolution of the three slags showed that the 2-day strength was higher for the samples with a higher amorphous fraction, while after 28 days, this influence was less pronounced.     

Developing an Antibody–Drug Conjugate Approach to Selective Inhibition of an Extracellular Protein

Antibody–drug conjugates (ADCs) are a growing class of therapeutics that harness the specificity of antibodies and the cell-killing potency of small-molecule drugs. Beyond cytotoxics, there are few examples of the application of an ADC approach to difficult drug discovery targets. Here, we present the initial development of a non-internalising ADC, with a view to selectively inhibiting an extracellular protein. Employing the wellinvestigated matrix metalloproteinase-9 (MMP-9) as our model, we adapted a broad-spectrum, nonselective MMP inhibitor for conjugation and linked this to a MMP-9-targeting antibody. The resulting ADC fully inhibits MMP-9, and ELISA results suggest antibody targeting can direct a nonselective inhibitor.     

Inorganic polymers made of fayalite slag: On the microstructure and behavior of Fe

The microstructure of inorganic polymers (IP) formed from fayalite slag was investigated as a function of the composition of different activating solutions. The starting slag was 80 wt% amorphous, and after activation using sodium silicate solutions with varying SiO₂/Na₂O molar ratios, the amorphous phase dissolved and a binder phase was formed. The morphology of this binder, including the population and size of remnant particles and pores, was dependent on the particular activating solution used, and became denser as the level of silicate rose. ⁵⁷Fe Mössbauer spectroscopy revealed that the IP synthesis reaction is combined with the oxidation of Fe²⁺ from the fayalite slag to Fe³⁺ in the inorganic polymer binder. The reaction extent varied and could be quantified using the absorption areas of these ions. Data corroborate that the Fe²⁺ ions in the amorphous part of the fayalite slag and the Fe³⁺ ions in the new binder phase had an average oxygen‐coordination number of 5.     

Blends of Two Perylene Derivatives: Mesogenic Properties and Application As Emitter Materials in OLEDs

Blends consisting of two components, namely a liquid crystalline perylene ester and a bilaterally extended perylene ester, were studied. The liquid crystalline properties of these blends were investigated in detail by means of polarized optical microscopy and differential scanning calorimetry. The resulting phase diagram was used to explore the potential of these blends as emitter layers in OLEDs, which were prepared via thermal evaporation in a vacuum and spin coating of solutions.     

Predicting the site specific soil N supply under winter wheat in Germany

The expected amount of plant nitrogen (N) at harvest which originates from soil N supply is of high relevance for N fertilization planning. Due to mineralization–immobilisation turnover processes, soil N supply is influenced by N fertilization which complicates its assessment. The soil N supply consists of two components: the soil mineral N measured at early spring and the ‘effective’ N mineralization (Min^eff) under winter wheat (Triticum aestivum L.). Min^eff was defined as the difference between crop N uptake (N^crop) at harvest and N supply. Our aim was the identification and quantification of climate and site-related factors in order to achieve an improved assessment of the site-specific (long term average) Min^eff. We used N rate experiments from 411 collective seasons, carried out at 98 sites across Germany in order to analyze the impact of climate and site-related factors on Min^eff. Quadratic curves were fitted in order to describe the grain N uptake as a function of N supply. A fixed marginal N efficiency was defined in order to analyze Min^eff at a reasonable N supply. Starting with estimates for Min^eff as function of preceding crop, we found that climate (average temperature during May, annual rainfall) and site-related factors have a significant influence on Min^eff. In order to ensure that the regression model is transferable to unknown sites, a “leave one site out” cross validation was carried out. Compared to considering preceding crop only (reference), the regression model reduced the RMSE by 9.5 (calibration) or 8.3 (cross validation) kg N/ha.     

Graph Searching, Elimination Trees, and a Generalization of Bandwidth

The bandwidth minimization problem has a long history and a number of practical applications. In this paper we introduce a natural extension of bandwidth to partially ordered layouts. We consider this extension from three main viewpoints: graph searching, tree decompositions, and elimination orderings. The three graph parameters pathwidth, profile, and bandwidth related to linear layouts can be defined by variants of graph searching using a standard fugitive. Switching to an inert fugitive, the two former parameters are extended to treewidth and fill-in, and our first viewpoint considers the analogous tree-like extension that arises from the bandwidth variant. Bandwidth also has a definition in terms of ordered path decompositions, and our second viewpoint extends this in a natural way to ordered tree decompositions. In showing that both extensions are equivalent we employ the third viewpoint of elimination trees, as used in the field of sparse matrix computations. We call the resulting parameter the treespan of a graph and prove some of its combinatorial and algorithmic properties.     

Breaking Symmetries and Constraints: Transitions from 2D to 3D in Passive Walkers

The inherent dynamics of bipedal, passive mechanisms are studiedto investigate the relation between motions constrained to two-dimensional (2D)planes and those free to move in a three-dimensional (3D) environment. Inparticular, we develop numerical and analytical techniques usingdynamical-systems methodology to address the persistence and stabilitychanges of periodic, gait-like motions due to the relaxation ofconfiguration constraints and the breaking of problem symmetries. Theresults indicate the limitations of a 2D analysis to predictthe dynamics in the 3D environment. For example, it is shownhow the loss of constraints may introduce characteristically non-2Dinstability mechanisms, and how small symmetry-breaking terms may result inthe termination of solution branches.     

Appearance-based face recognition and light-fields

Arguably the most important decision to be made when developing an object recognition algorithm is selecting the scene measurements or features on which to base the algorithm. In appearance-based object recognition, the features are chosen to be the pixel intensity values in an image of the object. These pixel intensities correspond directly to the radiance of light emitted from the object along certain rays in space. The set of all such radiance values over all possible rays is known as the plenoptic function or light-field. In this paper, we develop a theory of appearance-based object recognition from light-fields. This theory leads directly to an algorithm for face recognition across pose that uses as many images of the face as are available, from one upwards. All of the pixels, whichever image they come from, are treated equally and used to estimate the (eigen) light-field of the object. The eigen light-field is then used as the set of features on which to base recognition, analogously to how the pixel intensities are used in appearance-based face and object recognition.     

Fault‐Tolerant Control Allocation for Overactuated Nonlinear Systems

This paper addresses the problem of fault‐tolerant control allocation for input affine nonlinear systems. The proposed scheme is divided in three main tasks: fault detection and estimation using a nonlinear observer, fault isolation through a bank of unknown input observers with a resetting policy to reduce the effects of nonlinearities and control reconfiguration based on reduced order allocation. Analytical results regarding the isolability and reconfigurability of actuator faults are derived and a simulation example is used to illustrate the the proposed fault tolerant control methodology.     

Solders development and application process for a micro chip-camera

Nowadays, micro components have to fulfill rising optical requirements for different scientific and industrial fields like astronomy, medicine or multimedia. For this purpose, advanced miniaturized chip-cameras are produced for the microsystems engineering market. The assembly and joining technologies play a very important role in the production of these micro components. Several challenges are associated with the joining of chip-cameras. In this study, the application of the soldering technology has been considered in order to face these challenges. Two joining technologies have been investigated: active soldering and transient liquid phase (TLP) bonding. Both soldering processes have shown a big potential for hybrid microsystems joining in previous studies. For both processes, soldering alloys and parameters have been conceived in order to fulfill the joining requirements of the micro camera components. For instance, the joining temperature represents a major challenge because the chip-camera consists of a plastic material, polymethyl methacrylate (PMMA). Therefore, particular attention has been directed to the soldering as well as to the coating temperature. The experimental investigations concerning the solders application through physical vapor deposition (PVD) have been supported by finite element method (FEM) simulations. The analysis of  the temperature distribution in the micro components during the coating process was the focus of  the calculations. Possible undesirable local overheated areas of the chip-camera components can be detected through simulation.

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