Ivory osteoma of the cervical spine: case report

OBJECTIVE AND IMPORTANCE: We report a unique case of ivory osteoma of the cervical spine. CLINICAL PRESENTATION: The clinical presentation was one of polyradicular deficit without myelopathy after trauma. The imaging characteristics and histology of the lesion were those of a classic ivory osteoma. INTERVENTION: A complete surgical excision of the lesion was accomplished. CONCLUSION: We think we have recorded the only well-documented case of ivory osteoma affecting the spine.     

The kininogen gene family in obstructive uropathy

Because many patients present themselves for treatment with both craniofacial and craniocervical pain, 2 questions arise: (1) What are the sensory and motor consequences of dysfunction in either of these areas on the other? (2) Do craniofacial and craniocervical pain have a similar cause? These questions formed the impetus for this review article. The phenomenon of concurrent pain in craniofacial and cervical structures is considered, and clinical reports and opinions are presented regarding theories of cervical-to-craniofacial and craniofacial-to-cervical pain referral. Because pain referral between these 2 areas requires anatomic and functional connectivity between trigeminally and cervically innervated structures, basic neurophysiologic and neuroanatomic literature is reviewed. The published data clearly demonstrate neurophysiologic and structural convergence of cervical sensory and muscle afferent inputs onto trigeminal subnucleus caudalis nociceptive and non-nociceptive neurons. Moreover, changes in metabolic activity and blood flow in the brainstem and cervical dorsal horn of the spinal cord in both monkeys and cats have been demonstrated after electric stimulation of the V1-innervated superior sagittal sinus. In conclusion, the animal experimental data support the findings of human empiric and experimental studies, which suggest that strong connectivity exists between trigeminal and cervical motor and sensory responses.     

All-trans beta-carotene is absorbed preferentially to 9-cis beta-carotene, but the latter accumulates in the tissues of domestic ferrets (Mustela putorius puro)

The algae Dunaliella bardawil and Dunaliella salina naturally contain large concentrations of all-trans and 9-cis beta-carotene (betaC). The purpose of this study was to compare the relative serum and tissue accumulation of all-trans and 9-cis betaC in ferrets fed different ratios of all-trans/9-cis betaC derived from two commercial sources, D. bardawil or D. salina (Betatene). Male ferrets (7 wk old) were fed carotene-free, pelleted diets for 27 d. Beginning on d 18, groups of ferrets (n = 6 or 7) received daily, one of six oral supplements varying in ratios of 9-cis and all-trans betaC mixed with approximately 1.0mL of Ensure. Four supplements containing 5.2-8.3 micromol total betaC were prepared from a 20% Betatene preparation, D. bardawil, a high-cis Betatene preparation, and Betatene further enriched in 9-cis betaC with all-trans betaC/9-cis betaC ratios of 2.2, 1.5, 0.6 and 0.4, respectively. Two control supplements, high and low betaC, were prepared from commercial betaC beadlets. The high control supplement had an all-trans/9-cis ratio of 19.0, whereas 9-cis betaC was not detected in the low supplement. On d 27, serum and tissues were obtained for HPLC analysis of betaC and its isomers. Analysis of livers showed that all-trans betaC was the primary isomer present, but 9-cis and other isomers were also detected in all groups. The hepatic all-trans/9-cis ratios were 5.9, 4.9, 2.5, 1.4, 52.2 and47.5, respectively, for the groups listed above. Lower amounts of all-trans and 9-cis betaC were found in kidneys compared with the liver, but ratios of all-trans/9-cis were not different among groups. Only trace amounts of 9-cis betaC were found in serum. These results demonstrate that the algae D. bardawil and D. salina provide a bioavailable source of betaC isomers, but, as in humans, absorption of 9-cis betaC is poor and any 9-cis betaC absorbed is apparently cleared by the liver.     

Deformation structure in a Ti-24Al-11Nb alloy

A Ti-24Al-11Nb alloy has been heat-treated so as to obtain a microstructure of coarse α₂ particles (D0₁₉ structure based on Ti₃Al) in a matrix of the ordered β_o phase (B2 structure based on Ti₂AlNb). Dislocation structures generated by tensile strains of ∼2 pct at room temperature have been analyzed by transmission electron microscopy The β_o phase is shown to deform inhomogeneously on {110}, {112}, and {123} planes by α/〈211〉 slip. The slipband structure is complex, consisting of segments of heavily pinned edge dislocations with periodic cross slip of screw components on to secondary slip planes. Incompatibility stresses at α₂/β_o interfaces can generate fine α[100] slip as well. The α₂ phase deforms independently by α dislocation slip. Slipbands in the β_o phase can shear the α₂ phase by activatingc +a/2 slip on and slip planes, as well asa slip on higher order pyramidal planes, where the parallelism of the specific slip system is permitted by the Burgers relationship between the two phases.     

Comparing ANN and GMM in a voice conversion framework

In this paper, we present a comparative analysis of artificial neural networks (ANNs) and Gaussian mixture models (GMMs) for design of voice conversion system using line spectral frequencies (LSFs) as feature vectors. Both the ANN and GMM based models are explored to capture nonlinear mapping functions for modifying the vocal tract characteristics of a source speaker according to a desired target speaker. The LSFs are used to represent the vocal tract transfer function of a particular speaker. Mapping of the intonation patterns (pitch contour) is carried out using a codebook based model at segmental level. The energy profile of the signal is modified using a fixed scaling factor defined between the source and target speakers at the segmental level. Two different methods for residual modification such as residual copying and residual selection methods are used to generate the target residual signal. The performance of ANN and GMM based voice conversion (VC) system are conducted using subjective and objective measures. The results indicate that the proposed ANN-based model using LSFs feature set may be used as an alternative to state-of-the-art GMM-based models used to design a voice conversion system.     

Group technology based adaptive cell formation using predator-prey genetic algorithm

In recent years, there has been a considerable growth of application of group technology in cellular manufacturing. This has led to investigation of the primary cell formation problem (CFP), both in classical and soft-computing domain. Compared to more well-known and analytical techniques like mathematical programming which have been used rigorously to solve CFPs, heuristic approaches have yet gained the same level of acceptance. In the last decade we have seen some fruitful attempts to use evolutionary techniques like genetic algorithm (GA) and Ant Colony Optimization to find solutions of the CFP. The primary aim of this study is to investigate the applicability of a fine grain variant of the predator-prey GA (PPGA) in CFPs. The algorithm has been adapted to emphasize local selection strategy and to maintain a reasonable balance between prey and predator population, while avoiding premature convergence. The results show that the algorithm is competitive in identifying machine-part clusters from the initial CFP matrix with significantly less number of iterations. The algorithm scaled efficiently for large size problems with competitive performance. Optimal cluster identification is then followed by removal of the bottleneck elements to give a final solution with minimum inter-cluster transition cost. The results give considerable impetus to study similar NP-complete combinatorial problems using fine-grain GAs in future.