Precise interferometric length and phase-change measurement of gauge blocks based on reproducible wringing

A modern fringe-pattern-analyzing interferometer with a resolution of 1 x 10(-9) and without exclusion of systematic uncertainties owing to optic effects of less than 1 nm was used to test a new method of interferometric length measurement based on a combination of the reproducible wringing and slave-block techniques. Measurements without excessive wringing film error are demonstrated for blocks with nominal lengths of 2-6 mm and with high surface flatness. The uncertainty achieved for these blocks is less than 1 nm. Deformations of steel gauge blocks and reference platens, caused by wringing forces, are investigated, and the necessary conditions for reproducible wringing are outlined. A subnanometer uncertainty level in phase-change-correction measurements has been achieved for gauge blocks as long as 100 mm. Limitations on the accuracy standard method of interferometric length measurements and shortcomings of the present definition of the length of the material artifact are emphasized.     

The crystal structure of the processive endocellulase CelF of Clostridium cellulolyticum in complex with a thiooligosaccharide inhibitor at 2.0 A resolution

The mesophilic bacterium Clostridium cellulolyticum exports multienzyme complexes called cellulosomes to digest cellulose. One of the three major components of the cellulosome is the processive endocellulase CelF. The crystal structure of the catalytic domain of CelF in complex with two molecules of a thiooligosaccharide inhibitor was determined at 2.0 A resolution. This is the first three-dimensional structure to be solved of a member of the family 48 glycosyl hydrolases. The structure consists of an (alpha alpha)6-helix barrel with long loops on the N-terminal side of the inner helices, which form a tunnel, and an open cleft region covering one side of the barrel. One inhibitor molecule is enclosed in the tunnel, the other exposed in the open cleft. The active centre is located in a depression at the junction of the cleft and tunnel regions. Glu55 is the proposed proton donor in the cleavage reaction, while the corresponding base is proposed to be either Glu44 or Asp230. The orientation of the reducing ends of the inhibitor molecules together with the chain translation through the tunnel in the direction of the active centre indicates that CelF cleaves processively cellobiose from the reducing to the non-reducing end of the cellulose chain.     

Small-Signal Dynamic Analysis of Regulated Class E DC/DC Converters

Class E dc/dc converters can operate at high switching frequencies with very low switching power losses. Using commercially available power transistors and diodes, Class E converters can operate at switching frequencies in the low-MHz range, with efficiencies of about 85 percent. Previous papers dealt with the circuit parameter values needed to obtain high-efficiency operation and output-voltage regulation, and with the static control characteristics of the Class E dc/dc converter cell. The analysis is extended to include the dynamic control characteristics and further information about the static characteristics. The theoretical predictions are verified by experimental measurements on a 40-W 1.5-MHz converter.     

Developing an inpatient practicum program for patients with serious and persistent mental illness.

Training psychology students to treat patients with serious and persistent mental illness (SPMI) can provide an excellent opportunity for psychologists to help an historically disenfranchised and ignored population. With proper training, psychologists can play an important role in the development, provision, and administration of services to people with SPMI. We outline some of the issues to be considered in developing such a training program for practicum students, discuss the clinical skills and systemic issues that need to be mastered at the graduate level, and delineate the process by which this can be achieved in an inpatient, acute-care setting. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychologists in state mental hospitals: Problems and recommendations.

Psychology as a discipline has contributed significantly to the development of new treatment methods for severe behavior problems such as those found in the chronically mentally ill. Nevertheless, there are relatively few psychologists practicing in state mental hospitals, and it is difficult to attract and retain young qualified psychologists in these settings. The current article examines some of the more common problems that psychologists face in state facilities, with specific focus on organizational, physician-related, and staff-related issues. Recommendations are provided on ways to cope with problems in these three areas. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Use of X-ray fluorescence for sorting vinyl from other packaging materials in municipal solid waste

X-ray fluorescence of the chlorine atom is a suitable method for identifying vinyl in a mixed plastics stream in municipal solid waste. The chlorine X-ray is weak and does not penetrate paper labels. There is also a rapid decrease in measured chlorine X-ray intensity as the sample is moved away from the X-ray source and detector which could be a potential problem for bottles of uneven shape.     

Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis

Objective

To evaluate three-dimensional T2-weighted fast spin echo triple inversion recovery sequences (STIR+) for the diagnosis of myocardial edema in patients with suspected early myocarditis after respiratory or gastrointestinal tract viral infection and at follow-up.

Materials and methods

We prospectively examined 28 patients with suspected myocarditis and 37 controls matched for gender and age. An ECG-triggered STIR+ was used to cover the entire left ventricle in short-axis images with 10-mm slice thickness and no interslice gap. The global signal intensity ratio (heart muscle in relation to skeletal muscle) was calculated (global STIR+ ratio) to evaluate edema. All patients had repeat examinations at follow-up (mean interval 4.9 months, 1–12 months).

Results

The mean global STIR+ ratio was 2.15 ± 0.4 in the initial examination of patients as compared to 1.78 ± 0.3 in controls (p < 0.0001) and 1.89 ± 0.3 in patients at follow-up (p = 0.0001 vs. first visit). Left ventricular ejection fraction did not differ between patients and controls at baseline and at follow-up.

Conclusion

We could identify a significantly higher global STIR+ ratio in patients with suspected myocarditis compared to controls, and a dynamic change during follow-up. The global STIR+ ratio may, therefore, be useful for the diagnosis of myocarditis and should be further explored.

     

Microstructural aspects of neutron embrittlement of reactor pressure vessel steels - A view from positron annihilation spectroscopy

A comprehensive review of positron annihilation studies of Cr---Mo---V reactor pressure vessel (RPV) steels (Soviet type 15Kh2MFA) in unirradiated and neutron irradiated states is presented. The influences of lattice defects, impurity atom distribution, irradiation temperature, flux and fluence of fast neutrons on positron annihilation parameters, especially during isochronal annealing, are discussed in terms of the positron trapping model. In contrast to the literature, where irradiation-enhanced Cu precipitates and solute coated microvoids are thought to be major defect types responsible for strengthening and hence embrittling of RPV steels, we suggest irradiation-induced precipitates, i.e. probably carbides, to play this role. Possibilities to probe this model are suggested.