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61.
Theoretical analyses for the single fibre pull-out and push-out models under monotonic loading are given which are based on a shear-lag analysis in a fracture mechanics approach considering non-constant friction at the debonded interface as a result of fibre Poisson contraction (or expansion). The solutions allow the determination of typical fibre/matrix interfacial properties such as the interfacial fracture toughness, Gic, the coefficient of friction, μ, and the residual clamping stress, q0. Under cyclic loading the interfacial properties are expected to degrade as a result of repetitive abrasion, and a power law function is assumed between μ and the number of elapsed cycles, N. However, Gic is assumed to be unaffected and a fracture mechanics based debond criterion is derived for the relationship between the external applied stress, the debond length and the reduced friction coefficient for both fibre pull-out and fibre push-out. In addition, the relative displacements between the free fibre end and the matrix top are obtained for cyclic fatigue when the fibre is loaded and unloaded. A relationship obtained for the protrusion (or intrusion) length in fibre pull-out (or push-out) experiments allows the severity of the interface frictional degradation to be evaluated and characterised. Similarities and differences in the frictional degradation behaviour between fibre pull-out and push-out are also identified. 相似文献
62.
In the present study, we examined the effect of the thromboxane/prostaglandin endoperoxide analogue U46619 on proliferation and hypertrophy in cultured rat vascular smooth muscle cells and the roles of protein kinase C and transforming growth factor-beta (TGF-beta) in the mediation of the hypertrophic response to U46619. Since an increase in basic fibroblast growth factor (bFGF) was previously shown to mediate the hypertrophic response to U46619, we also assessed the relationship between bFGF and TGF-beta in the expression of U46619 actions. U46619 increased [35S]methionine incorporation into protein and protein content of vascular smooth muscle cells but had no effect on cell number. A role for TGF-beta was supported by the following observations: (1) exogenous human TGF-beta 1 increased protein synthesis; (2) antibody to TGF-beta blocked both TGF-beta- and U46619-induced increases in protein content; (3) U46619 increased active and total TGF-beta bioactivities; and (4) the actions of U46619 on protein content and TGF-beta bioactivity were blocked by the thromboxane/prostaglandin endoperoxide receptor antagonist SQ 29,548. Previous observations had demonstrated a role for bFGF in the expression of U46619 actions on protein synthesis. Results of the present study suggest that TGF-beta and bFGF interact in mediating the protein synthetic response to U46619. First, the concentration of exogenous TGF-beta (10 pmol/L) alone required to produce a protein synthetic response equivalent to that induced by U46619 was much higher than the concentration of endogenous active TGF-beta that accumulated in the media in response to U46619 (0.7 pmol/L). Second, bFGF (20 ng/mL) increased total TGF-beta bioactivity and stimulated protein synthesis. The hyper-trophic response to bFGF was blocked by anti-TGF-beta. The ability of U46619 and bFGF to increase protein synthesis and protein content in vascular smooth muscle cells was associated with TGF-beta-induced suppression of proliferation, as evidenced by the ability of antibody to TGF-beta to enhance U46619- and bFGF-induced increases in [3H]thymidine incorporation into DNA. Results of the present study also supported a role for protein kinase C in the expression of U46619 and bFGF actions. U46619 increased protein kinase C activity in the particulate fraction of vascular smooth muscle cells. Moreover, the protein kinase C inhibitors GF109203X and staurosporine blocked U46619- and bFGF-induced increases in protein synthesis as well as active and total TGF-beta bioactivities. By contrast, the protein kinase C inhibitors did not prevent the increases in protein synthesis induced by exogenous TGF-beta. The results demonstrate that thromboxane/prostaglandin endoperoxide signals increased TGF-beta bioactivity via protein kinase C. Increases in both bFGF and TGF-beta are required for an optimal hypertrophic response to U46619. The hypertrophic response to TGF-beta occurs through a protein kinase C-independent pathway. 相似文献
63.
64.
Shaofeng Wang Yuan Hu Zhihua Lin Zhou Gui Zhengzhou Wang Zuyao Chen Weicheng Fan 《Polymer International》2003,52(6):1045-1049
Acrylonitrile–butadiene–styrene (ABS)/montmorillonite nanocomposites have been prepared using a direct melt intercalation technique by blending ABS and organophilic clay of two different particle sizes: OMTa (5 µm) and OMTb (38 µm). Their structure and flammability properties were characterized by X‐ray diffraction, high resolution electronic microscopy (HREM), thermogravimetric analysis (TGA) and cone calorimeter experiments. The results of HREM showed that ABS/5 wt% OMTa nanocomposite was a kind of intercalated–delaminated structure, while ABS/5 wt% OMTb nanocomposite was mainly an intercalated structure. The nanocomposites showed a lower heat release rate peak and higher thermal stability than the original ABS by TGA and cone calorimeter experiments. Also, the intercalated nanocomposite was more effective than an exfoliated–intercalated nanocomposite in fire retardancy. Copyright © 2003 Society of Chemical Industry 相似文献
65.
本文利用最优回归设计“310”方案,研究了黑土地甜菜 Zn、K_2O、B的效果及合理施用问题。得出甜菜块根产量、含糖、产糖量、灰分 K 和有害 N 与 ZnK_2O、B 肥回归关系显著的回归模型,分析了 Zn、K_2O、B 对上述五个指标的效应,明确了 Zn 是影响各项指标的主要因子,并采用频率筛选法,提出了兼顾上述五项指标的优质高产施肥措施。 相似文献
66.
周庆民 《现代制造技术与装备》2003,(1):41-42
建厂已近60年的博山电机厂,在企业发展的历史上曾经有过辉煌:40年代,作为军工厂,在抗日战争的烽火和解放战争的硝烟中为新中国的解放事业做出了很大的贡献;50年代,作为全国八大电机厂之一,又为新中国的建设事业提供了许多优良的产品,而且作为汽车电机、直流微电机、交流 相似文献
67.
68.
分布系统中多米诺效应的分析与消除 总被引:3,自引:0,他引:3
分布系统中发生故障后,错误信息在进程间的传播,以及由此引起的系统恢复过程中的多米诺效应是分布系统容错恢复技术所面临的最重要与最困难的问题.目前各种研究工作偏重于具体的系统动态恢复技术.本文的研究重点在于首次揭示多米诺效应本身固有的数量特征及其与分布系统技术参数间的联系,给出多米诺效应动态消除技术,引入系统额外开销的下限,并针对动态技术的缺点,探讨多米诺效应的静态消除技术,为解决困难开辟新途径. 相似文献
69.
70.
Yang Lüyun 《中国稀土学报(英文版)》2006,24(Z2)
The fabrication of one kind of large core area Nd3 doped silicate glass photonic crystal fiber, and demonstration of the fiber's waveguidence properties were reported. This fiber owns a random air hole distribution in the cladding. The measured minimum loss of this kind of fiber is 10 dB·m-1 at 660 nm. These fibers can sustain only a single mode at least over wavelength ranging from 660 nm to 980 nm. 相似文献