Numerical study of steady turbulent flow through bifurcated nozzles in continuous casting

Bifurcated nozzles are used in continuous casting of molten steel, where they influence the quality of the cast steel slabs. The present study performs two-dimensional (2-D) and three-dimensional (3-D) simulations of steady turbulent(K- ε) flow in bifurcated nozzles, using a finite-element (FIDAP) model, which has been verified previously with water model experiments. The effects of nozzle design and casting process operating variables on the jet characteristics exiting the nozzle are investigated. The nozzle design parameters studied include the shape, angle, height, width, and thickness of the ports and the bottom geometry. The process operating practices include inlet velocity profile and angle as well as port curvature caused by erosion or inclusion buildup. Results show that the jet angle is controlled mainly by the port angle but is steeper with larger port area and thinner walls. The degree of swirl is increased by larger or rounder ports. The effective port area, where there is no recirculation, is increased by smaller or curved ports. Flow asymmetry is more severe with skewed or angled inlet conditions or unequal port sizes. Turbulence levels in the jet are higher with higher casting speed and smaller ports. Formerly Research Assistant, Department of Mechanical and Industrial Engineering. Formerly Research Assistant in the same department.     

Nanoparticles in Catalysis

In this article, we report studies of two new forms of highly active supported catalysts. First, those derived from supported carbonylate clusters—nanocatalysts and second, those produced from the heterogenization of known chiral homogeneous systems. The utilization of established cluster compounds of precisely known composition and structure have proved invaluable in the preparation of mixed metal nanoparticles of well-defined composition. The attachment of these nanoparticles to the inner walls of mesoporous silica has led to the development of highly active and effective catalysts for a series of hydrogenation reactions, emphasizing the enhanced reactivity of these metal systems as a consequence of their size and of the low coordination numbers of the metal atoms involved. These attributes combined with the relative ease of characterization of both the active sites and their location has led to a detailed examination of the role of these nanosystems in a new approach to clean technology. In an alternative strategy, the use of heterogenized homogeneous chiral catalysts based on the ferrocenyl moiety and diamino ligands and linked to the inner surface of mesoporous materials either by a direct chemical bond or by an ionic interaction has also been explored. These catalysts have been shown to be highly effective in the enantioselective synthesis of organic compounds. Significantly, we have found that the mesopore (usually MCM-41) imposes spatial restrictions arising from the concavity of the inner surface and leads to greatly enhanced enantioselective (ee) performance.     

Factors influencing learning through play in ICT settings

Using a mixed method approach of questionnaires, observations and field notes, the authors have studied a number of settings during the past two years which have focussed on the development of ICT capability through play. Some of these have involved children identified as disaffected or disadvantaged, whilst others have involved initial teacher education students. In this paper, we consider some of the results obtained from the most recent of these settings, relate these to those obtained from the other settings, and explore further a number of inter-related issues which have arisen from the analysis. We particularly focus on the effect of learners’ self-esteem and self-efficacy; the influence of gender-related characteristics; the role of interaction between learners during activity; and the value of reflection.     

Allelotype analysis of uterine leiomyoma: localization of a potential tumor suppressor gene to a 4-cM region of chromosome 7q

The degree and nature of patient involvement in consultations with health professionals influences problem and needs recognition and management, and public accountability. This paper suggests a framework for understanding the scope for patient involvement in such consultations. Patients are defined as co-producers of formal health services, whose potential for involvement in consultations depends on their personal rights, responsibilities and preferences. Patients' rights in consultations are poorly defined and, in the National Health Service (NHS), not legally enforceable. The responsibilities of patients are also undefined. I suggest that these are not to deny, of their own volition, the rights of others, which in consultations necessitate mutuality of involvement through information-exchange and shared decision-making. Preferences should be met insofar as they do not militate against responsibilities and rights.     

Full expression of the exaggerated salt appetite of the spontaneously hypertensive rat requires a prenatal factor

1. The spontaneously hypertensive rat (SHR) exhibits a lower bodyweight in utero and an exaggerated salt appetite post partum. To determine whether salt appetite is affected by the perinatal environment, we measured the salt appetite of embryo-cross-transferred SHR and Wistar Kyoto (WKY) rats at maturity. 2. One-cell embryos were collected from the oviducts of donor rats and transferred into the oviducts of recipients through the infundibulum. The salt appetite of the resultant female offspring for 0.10 and 0.15 mol/L saline was measured at 20-30 weeks of age. 3. Salt intake of SHR gestated in WKY rats was significantly lower than that of SHR gestated in SHR, while that of WKY rats gestated in SHR was higher than that of WKY rats gestated in WKY rats. 4. Therefore, some maternal factor plays a role in the development of the exaggerated salt appetite of the SHR. This factor is also able to affect the later salt appetite of WKY rat offspring born to SHR surrogates.     

Diagnosis of fetal renal anomalies

Urinary tract abnormalities are fairly common in the perinatal period. Ultrasonography is an effective diagnostic tool for identifying fetal urinary tract anomalies and can be helpful in establishing prognosis and guiding treatment decisions. The sonographer is encouraged to characterize and localize the fetal urinary tract abnormality when identified. In doing so, the correct diagnosis can be selected from the differential possibilities, providing vital clinical information needed to develop a care plan for both the pregnant woman and her fetus.     

Analysis of regulated exocytosis in adrenal chromaffin cells: insights into NSF/SNAP/SNARE function

In a duplicate study during 1987-1991, 478 24-h duplicate samples from 14 homes for elderly people and 10 homes for youth were investigated for their contents of selected harmful substances. The analyses covered 45 active substances of pesticides, 17 PCB-congeners as well as lead, cadmium, and nitrate contents. Pesticides could be detected only in 15% of the investigated samples. The pesticide contents reached max. 8% of the respective FAO/WHO-limits. As the mean intake of the three most important PCB-congeners (sum of the congeners 138, 153, and 180) values of 0.9 and 1.1 micrograms per day and ration or person, respectively, were found. Also in the worst case the daily PCB intake was below the recommended ADI value of the FDA of 1 microgram/kg of body weight. The daily nutritional intake of lead and cadmium via the investigated daily rations reached about 5.6% and 20% of the Provisionally Tolerably Weekly Intake values of the FAO/WHO. The mean nitrate content of the duplicate portions was 101 mg per day and person (median: 79 mg per day and person). Referred to the median value the WHO limit (3.65 mg/kg body weight and day) was exhausted to about 36%.     

Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse

A DNA fragment containing the recA gene of Gluconobacter oxydans was isolated and further characterized for its nucleotide sequence and ability to functionally complement various recA mutations. When expressed in an Escherichia coli recA host, the G. oxydans recA protein could efficiently function in homologous recombination and DNA damage repair. The recA gene's nucleotide sequence analysis revealed a protein of 344 amino acids with a molecular mass of 38 kDa. We observed an E. coli-like LexA repressor-binding site in the G. oxydans recA gene promoter region, suggesting that a LexA-like mediated response system may exist in G. oxydans. The expression of G. oxydans recA in E. coli RR1, a recA+ strain, surprisingly caused a remarkable reduction of the host wild-type recA gene function, whereas the expression of both Serratia marcescens recA and Pseudomonas aeruginosa recA gene caused only a slight inhibitory effect on function of the host wild-type recA gene product. Compared with the E. coli RecA protein, the identity of the amino acid sequence of G. oxydans RecA protein is much lower than those RecA proteins of both S. marcescens and Pseudomonas aeruginosa. This result suggests that the expression of another wild-type RecA could interfere with host wild-type recA gene's function, and the extent of such an interference is possibly correlated to the identity of the amino acid sequence between the two classes of RecA protein.     

Delaminations at the free edge of a composite laminate

The concept of a fracture process zone where damage takes place is used to analyse the delaminations at the free edges of angle ply laminates under uniaxial tension. The use of a fracture process zone removes the singularity in the interlaminar stresses and enables the initiation and growth of delaminations to be modelled for a perfect laminate without any assumed prior defects. Two different models for the stress displacement relationship in the fracture process zone are examined: a constant stress up to critical displacement and a linear relationship. Finite element analysis shows that there is little difference in the predictions obtained from the two models. An approximate analysis is presented for the constant stress stress-displacement model which is shown to agree with a finite element solution and experimental data. Hence it is argued that the approximate method using a constant stress model for the fracture process zone is sufficient for accurate prediction of delaminations.