WO3 pillar-type and helical-type thin film structures to be used in microbatteries

In the present study WO₃ thin films were deposited by sputtering onto ITO glass, W/ITO and Si substrates by using the glancing angle deposition (GLAD) technique, with the objective of applying these materials in electrochemical intercalation devices. The thin films microstructure and electrochemical behavior were determined through scanning electron microscopy (SEM) and cycling at constant current with potential limitation. By mainly adjusting the substrate holder speed rotation, pillar-type and helical-type structures were obtained under high and low speed rotation levels, respectively. The electrochemical results showed that the best charge capacity performance was obtained for the WO₃/W/ITO films with pillar-type structures, which are more porous.     

SIR-C data quality and calibration results

The SIR-C/X-SAR imaging radar took its first flight on the Space Shuttle Endeavour in April 1994 and flew for a second time in October 1994. This multifrequency radar has fully polarimetric capability at L- and C-band, and a single polarization at X-band (X-SAR). The Endeavour missions were designated the Space Radar Laboratory-1 (SRL-1) and -2 (SRL-2). Calibration of polarimetric L- and C-band data for all the different modes SIR-C offers is an especially complicated problem. The solution involves extensive analysis of pre-flight test data to come up with a model of the system, analysis of in-flight test data to determine the antenna pattern and gains of the system during operation, and analysis of data from over fourteen calibration sites distributed around the SIR-C/X-SAR orbit track. The SRL missions were the first time a multifrequency polarimetric imaging radar employing a phased array antenna has been flown in space. Calibration of SIR-C data products involved some unique technical problems given the complexity of the radar system. In this paper, the approach adopted for calibration of SIR-C data is described and the calibration performance of the data products is presented     

Designing collaborative,constructionist and contextual applications for handheld devices

This paper explores current applications for handheld devices and questions which of these make full use of the unique attributes of handheld devices in order to facilitate learning in a pedagogically sensible manner. In order to do so, the paper presents a functional framework which analyses handheld application in relation to their use as well as the pedagogical underpinning, if any, that informs their development. Our framework currently consists of seven distinct categories of application, which we term: administrative, referential, interactive, microworld, data collection, location aware and collaborative. We argue that three categories, namely data collection, location aware and collaborative, are particularly suited to learning with handheld devices when they are informed by collaborative, contextual and constructionist learning theories. Furthermore, we contend that applications of the type just outlined deserve further research since they are not attempting to replicate, or even augment, existing learning scenarios but rather they try to create new learning opportunities which would not be possible without (mobile) technology. Finally, the authors introduce a number of applications and learning scenarios that they have developed for handheld devices and explain their position within the framework.     

Wood processing variables and adhesive joint performance

In order to obtain a bonded wood product from the tree, wood must be subjected to a series of processes. These include, among others, vital processes like drying of the green wood and machining of the surfaces of the dried wood in preparation for bonding. However, when wood is machined with dull blades, thermal degradation of the wood frequently occurs. The effects of kiln drying and thermal degradation of wood on the performance of the adhesive joints subsequently formed from such wood were investigated. Tapered double cantilever beam (TDCB) test specimens obtained from hard maple and phenol–resorcinol–formaldehyde (PRF) adhesives were used in the investigations. The enhancement of fracture energy due to the reduction in the moisture content of wood, the improved performance of adhesive joints due to rejointing of wood surfaces before bonding, and the reduction of adhesive joint strength resulting from thermal degradation of wood are presented and discussed.     

Geographic distribution and clinical description of leishmaniasis cases in Peru

Asymmetric acetylcholinesterase (AChE) is anchored to the basal lamina (BL) of cholinergic synapses via its collagenic tail, yet the complement of matrix receptors involved in its attachment remains unknown. The development of a novel overlay technique has allowed us to identify two Torpedo BL components that bind asymmetric AChE: a polypeptide of approximately 140 kDa and a doublet of 195-215 kDa. These were found to stain metachromatically with Coomassie blue R-250, were solubilized by acetic acid, and were sensitive to collagenase treatment. Upon sequence analysis, the 140 kDa polypeptide yielded a characteristic collagenous motif. Another AChE-binding BL constituent, identified by overlay, corresponded to a heparan sulfate proteoglycan. Lastly, we established that this proteoglycan, but not the collagenous proteins, interacted with at least one heparin binding domain of the collagenic tail of AChE. Our results indicate that at least two BL receptors are likely to exist for asymmetric AChE in Torpedo electric organ.     

Failure pressure evaluation of the containment building of a large dry nuclear power plant

The evaluation of the failure pressure of the containment building of a large dry PWR-W three loops nuclear power plant, based on computer numerical simulation, is described in this paper. The proposed method considers fully three-dimensional finite element models in order to take into account the effect of the most significant structural characteristics (presence of three buttresses, penetrations, additional reinforcement around the penetrations, etc.), the lack of symmetry of the forces generated by the prestressing system, as well as the nonlinear behaviour of the materials and the sensitivity of the results to uncertainties associated with several parameters. The computational model is completely described, including the constitutive equations for the concrete, the reinforcing steel and prestressing tendons, the spatial discretization—isoparametric elements including the reinforcement are used. The structural models and the analyses performed for their calibration are also described. The influence on the failure pressure of incorporating the foundation slab in the structural model, and the influence of the thermal effects, are discussed. One of the conclusions of the numerical study is that the failure process can be appropriately simulated by means of a structural model which does not include either the foundation slab or the thermal effects. Finally, results of a probabilistic simulation of the failure pressure are given.     

Single amino acid substitutions can further increase the stability of a thermophilic L-lactate dehydrogenase

Lactate dehydrogenases are of considerable interest as stereospecificcatalysts in the chemical preparation of enantiomerically pure-hydroxyacid synthons. For such applications in synthetic organicchemistry it would be desirable to have enzymes which tolerateelevated temperatures for prolonged reaction times, to increaseproductivity and to extend then applicability to poor substrates.Here, two examples are reported of significant thermostabilizations,induced by sitedirected mutagenesis, of an already thermostableprotein, the L-lactate dehydrogenase (EC 1.1.1.27 [EC] , 35 kDa permonomer subunit) from Bacillus stearothermophilus. Thermal inactivationof this enzyme is accompanied by irreversible unfolding of thenative protein structure. The replacement of Argl71 by Tyr stabilizesthe enzyme against thermal inactivation and unfolding. Thisstabilizing effect appears to be based on improved interactionsbetween the subunits in the core of the active dimeric or tetramericforms of the enzyme. The thermal stability of L-lactate dehydrogenasevariants with an active site Arg residue, either in the 171(wild-type) or in the 102 position, is further increased bysulfate ions. The two stabilizing effects are additive, as foundfor the Argl71Tyr/ Gln1O2Arg double mutant, for which the stabilityof the protein in 100 mM sulfate solution reaches that of L-lactatedehydrogenases from extreme thermophiles. All mutant proteinsretain significant catalytic activity, both in the presenceand absence of stnhilfoing salts, and are viable catalysts inpreparative scale reactions.     

Reliability of portal frames with discrete design variables

Virtually all structural optimization based on system reliability was conducted considering continuous design variables. The solution of the reliability-based design problem is obtained by solving alternatively a reliability assessment problem and an optimal sizing program until the best reliability-based design occurs. The reliability assessment problem is formulated as a linearly constrained concave quadratic program. By introducing the concept of segmental members, the discrete optimum design is achieved based upon linear programming. Examples are solved by employing the proposed computational technique.Presented at NATO ASI Optimization of Large Structural Systems, Berchtesgaden, Germany, Sept. 23 – Oct. 4, 1991