Effect of stents coated with a combination of sirolimus and alpha-lipoic acid in a porcine coronary restenosis model

The aim of this study was to evaluate antiproliferative sirolimus- and antioxidative alpha-lipoic acid (ALA)-eluting stents using biodegradable polymer [poly-l-lactic acid (PLA)] in a porcine coronary overstretch restenosis model. Forty coronary arteries of 20 pigs were randomized into four groups in which the coronary arteries had a bare metal stent (BMS, n = 10), ALA-eluting stent with PLA (AES, n = 10), sirolimus-eluting stent with PLA (SES, n = 10), or sirolimus- and ALA-eluting stent with PLA (SAS, n = 10). A histopathological analysis was performed 28 days after the stenting. The ALA and sirolimus released slowly over 30 days. There were no significant differences between groups in the injury or inflammation score; however, there were significant differences in the percent area of stenosis (56.2 ± 11.78 % in BMS vs. 51.5 ± 12.20 % in AES vs. 34.7 ± 7.23 % in SES vs. 28.7 ± 7.30 % in SAS, P < 0.0001) and fibrin score [1.0 (range 1.0–1.0) in BMS vs. 1.0 (range 1.0–1.0) in AES vs. 2.0 (range 2.0–2.0) in SES vs. 2.0 (range 2.0–2.0) in SAS, P < 0.0001] between the four groups. The percent area of stenosis based on micro-computed tomography corresponded with the restenosis rates based on histopathological stenosis in different proportions in the four groups (54.8 ± 7.88 % in BMS vs. 50.4 ± 14.87 % in AES vs. 34.5 ± 7.22 % in SES vs. 28.9 ± 7.22 % in SAS, P < 0.05). SAS showed a better neointimal inhibitory effect than BMS, AES, and SES at 1 month after stenting in a porcine coronary restenosis model. Therefore, SAS with PLA can be a useful drug combination for coronary stent coating to suppress neointimal hyperplasia.     

A new vertical‐alignment LC mode with high‐transmittance and fast‐response‐time features

Abstract— A novel pixel design for vertical‐alignment LCDs with superior transmittance has been developed. The new liquid‐crystal mode, refered to as the hole‐induced vertical‐alignment mode (Hi‐VA), uses a via hole of an organic layer on a TFT substrate to achieve multi‐domain alignment. Compared to the conventional design, the Hi‐VA mode has a transmittance of up to 135% with a contrast ratio of 2000:1. Moreover, the new structure is free from ITO patterning or protrusion on the color‐filter side, which makes the fabrication process simple and low cost.     

A dual‐polarized cylindrical conformal array antenna suitable for unmanned aerial vehicles

A dual‐polarized X‐band conformal array antenna is presented for unmanned aerial vehicles with polarimetric radars/sensors. Starting from the planar structure, the array antenna consisted of sixteen 2 × 2 subarrays is conformal to the cylinders with various curvature radii to fit the payload box of the airborne vehicle. The return losses are almost constant even if the curvature radius changes. Measured radiation patterns are compared with various curvatures at the same frequencies. The array can be easily placed on the aircraft payload or fuselage due to its ultra thin thickness, ultra lightweight, and conformal structure, which has potential airborne applications in polarimetric radar surveillance, remote sensing, and wireless communications. © 2010 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2011.     

Laser marking system for light guide panel using design of experiment and web-based prototyping

A light guide panel (LGP) is an element of the liquid crystal display (LCD) back light unit (BLU), which is used for display devices. In this study, the laser marking process is applied to the fabrication of light guide panels as the new fabrication process. In order to obtain a light guide panel which has high luminance and uniformity, four principal parameters such as power, scanning speed, ratio of line gap, and number of line were selected. A web-based design tool was developed to generate patterns of light guide panel via the network, and the tool may assist the designer to develop various prototype patterns. Topcon-BM7 was used for luminance measurement of each specimen with 100 mm×100 mm area. By Taguchi method, optimized levels of each parameter were found, and luminance of 3523 cd/cm² and uniformity of 92% were achieved using the laser machined BLU.     

Impact of a simple load balancing approach and an incentive-based scheme on MANET performance

Most reactive mobile ad hoc network (MANET) routing protocols such as AODV and DSR do not perform search for new routes until the network topology changes. But, low node mobility does not affect the MANET connectivity and the same routes may be used for a long time. This may cause concentration of traffic on few mobile stations (MSs), which results in congestion and hence longer end-to-end delay. In addition, continuous use of MSs may cause their battery power to get exhausted rapidly. Expiration of MS energy causes disruption of connections traversing through the MSs and could generate many simultaneous new routing requests. Therefore, we propose a load balancing approach called Simple Load Balancing Approach (SLBA), which can be transparently added to any current reactive routing protocol such as AODV and DSR. SLBA minimizes the traffic concentration by allowing each MS to drop RREQ or to give up packet forwarding depending on its own traffic load. Meanwhile, MSs may deliberately give up forwarding packets to save their own energy. For encouraging MSs to volunteer in forwarding packets, we introduce a reward scheme for packet forwarding, named Protocol-Independent Fairness Algorithm (PIFA). We compare the performance of AODV and DSR with and without SLBA and PIFA. Simulation results indicate that SLBA can distribute traffic very well and improve the MANET performance. PIFA is also observed to prevent MANET partitioning and any performance degradation due to selfish nodes.     

Two versions of architectures for dynamic implied addressing mode

The complexity of today’s embedded applications increases with various requirements such as execution time, code size or power consumption. To satisfy these requirements for performance, efficient instruction set design is one of the important issues because an instruction customized for specific applications can make better performance than multiple instructions in aspect of fast execution time, decrease of code size, and low power consumption. Limited encoding space, however, does not allow adding application specific and complex instructions freely to the instruction set architecture. To resolve this problem, conventional architectures increases free space for encoding by trimming excessive bits required beyond the fixed word length. This approach however shows severe weakness in terms of the complexity of compiler, code size and execution time. In this paper, we propose a new instruction encoding scheme based on the dynamic implied addressing mode (DIAM) to resolve limited encoding space and side-effect by trimming. We report our two versions of architectures to support our DIAM-based approach. In the first version, we use a special on-chip memory to store extra encoding information. In the second version, we replace the memory by a small on-chip buffer along with a special instruction. We also suggest a code generation algorithm to fully utilize DIAM. In our experiment, the architecture augmented with DIAM shows about 8% code size reduction and 18% speed up on average, as compared to the basic architecture without DIAM.     

Pattern recognition using feature feedback: Application to face recognition

In this paper, we propose a new pattern recognition method using feature feedback and present its application to face recognition. Conventional pattern recognition methods extract the features employed for classification using PCA, LDA and so on. On the other hand, in the proposed method, the extracted features are analyzed in the original space using feature feedback. Using reverse mapping from the extracted features to the original space, we can identify the important part of the original data that affects the classification. In this way, we can modify the data to obtain a higher classification rate, make it more compact or abbreviate the required sensors. To verify the applicability of the proposed method, we apply it to face recognition using the Yale Face Database. Each face image is divided into two parts, the important part and unimportant part, using feature feedback, and the classification performed using the feature mask obtained from feature feedback. Also, we combine face recognition with image compression. The experimental results show that the proposed method works well.     

Efficient RNTS system for privacy of banking off-line customer

With the development in IT technology and with growing demands of users, a ubiquitous environment is being made. Because individual identification is important in ubiquitous environment, RFID technology would be used frequently. RFID is a radio frequency identification technology to replace bar code. The reader transmits query (request of user information) and tag-provides user information. RFID has various advantages, such as high speed identification rates, mass memory storages. However, eavesdropping is possible as well as a problem that user information is exposed (Juels et al. in Conference on Computer and Communications Security—ACM CCS, pp. 103–111, 2003; Ohkubo et al. in RFID Privacy Workshop 2003; Weis et al. in International Conference on Security in Pervasive Computing, pp. 201–212, 2003; Weis et al. in Cryptographic Hardware and Embedded Systems—CHES, pp. 454–469, 2002). Therefore, when off-line customer had visited bank for banking service, RNTS (RFID number ticket service) system provides both anonymity in customer identification and efficiency of banking service. In addition, RNTS system protects privacy of an off-line user visiting the bank and it is an efficient method offering service in order of arriving in the bank.