Strategies for preserving the confidentiality of psychological reports.

Describes strategies that appear to be effective in reducing breaches of confidentiality due to unauthorized dissemination of psychological reports. Strategies suggested include (1) clarifying the word "confidentiality," (2) not placing psychological reports in general medical records, and (3) insisting that forms authorizing release of information specifically name the psychology department or an individual staff member. It is concluded that operationally defining in the report itself how the report is to be treated is a complementary strategy that may help reduce breaches of confidentiality. (French abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Respiratory failure in acute pancreatitis: the role of free fatty acids

Hypertriglyceridemia has been noted in patients with acute pancreatitis and respiratory failure. Utilizing an isolated, perfused, canine pulmonary lobe, the effect of triglyceride infusion on pulmonary function was evaluated. When heparin was used to anticoagulate the perfusion circuit, the addition of triglyceride to the autologous blood perfusate resulted in massive weight gain (226 gm), intrapulmonary shunting (36%), and a marked drop in pulmonary compliance (congruent to 50%). Heparin activates lipoprotein lipase, and therefore some triglyceride in the perfusate was lipolyzed with a resultant increase in serum free fatty acids (FFAs) to 253 mumole/dl. When anticoagulation of the perfusion circuit was accomplished by defibrinogenation with Arvin, the addition of triglyceride to the autologous blood perfusate caused minimal weight gain (28 gm), no intrapulmonary shunting, and only a slight decrease in pulmonary compliance (22%). Arvin has no effect on lipoprotein lipase, and the FFA level in the perfusate remained normal (less than 70 mumole/dl). Thus it appears that FFA release secondary to the action of pulmonary lipoprotein lipase on blood triglyceride is the important pathogenic step in the induction of respiratory failure in this model.     

Effects of poor solvents on radical-radical termination of polymerization

It is shown that in poor solvents for the polymer the rate coefficient for radical-radical termination in the polymerization of styrene and methyl methacrylate is diminished compared with that in bulk monomer. It is suggested that this effect is due to the formation of tightly coiled macroradicals which hinder the radical-radical reaction process.     

Addition of sec-butyllithium to m-diisopropenylbenzene

The reaction of equivalent quantities of sec-butyllithium with m-diisopropenylbenzene in cyclohexane and benzene solution in the presence and absence of catalytic amounts of triethylamine, does not yield the diadduct quantitatively. Oligomer formation occurs to varying extents depending on the reaction conditions, and, contrary to claims in the literature, this may not be a good route to a difunctional initiator for anionic polymerization.     

The crash reduction effectiveness of a network-wide traffic police deployment system

Random Road Watch (RRW) is a traffic policing program in operation in Queensland, Australia. It differs from conventional traffic policing in that an explicit resource management technique is used which randomly schedules low levels of police enforcement in a manner intended to provide long-term, widespread coverage of a road network and hence maximise road safety benefits. Implementation of the program studied in Queensland covered 55% of total crashes within the state. This study aimed to measure the crash effects of the RRW program in Queensland. A quasi-experimental study design was used for the evaluation incorporating Poisson regression statistical analysis techniques. Analysis of the effects of the Queensland RRW program on crash frequency has shown the program to be effective overall. Estimated program effects were largest on fatal crashes, with an estimated reduction of 31%. Estimated aggregate program crash effects reduced with crash severity and increased with time after program introduction. Crash reductions in the third year after program introduction translated into savings, at state level, of some 12% of the state's crashes of all severities and some 15% of the state's fatal road crashes. Overall, the program produced a significant 11% reduction in total crashes in areas outside of metropolitan Brisbane. The opportunity-cost benefit/cost ratio for the program was estimated to be 55:1.     

SR-30 turbojet engine real-time sensor health monitoring using neural networks,and Bayesian belief networks

This paper describes the use of artificial intelligence-based techniques for detecting and isolating sensor failures in a turbojet engine. Specifically, three artificial intelligence (AI) techniques are employed: artificial neural networks (NNs), statistical expectations, and Bayesian belief networks (BBNs). These techniques are combined into an overall system that is capable of distinguishing between sensor failure and engine failure—a critical capability in the operation of turbojet engines. The turbojet engine used in this study is an SR-30 developed by Turbine Technologies. Initially, NNs were designed and trained to recognize sensor failure in the engine. The increased random noise output from failing sensors was used as the key indicator. Next, a Bayesian statistical method was used to recognize sensor failure based on the bias error occurring in the sensors. Finally, a BBN was developed to interpret the results of the NN and statistical evaluations. The BBN determines whether single or multiple sensor failures signify engine failure, or whether sensor failures represent separate, unrelated incidences. The BBN algorithm is also used to distinguish between bias and noise errors on sensors used to monitor turbojet performance. The overall system is demonstrated to work equally well during start-up and main-stage operation of the engine. Results show that the method can efficiently detect and isolate single or multiple sensor failures within this dynamic environment.     

N‐Arylsulfonyl Indolines as Retinoic Acid Receptor‐Related Orphan Receptor γ (RORγ) Agonists

The nuclear retinoic acid receptor‐related orphan receptor γ (RORγ; NR1F3) is a key regulator of inflammatory gene programs involved in T helper 17 (T_H17) cell proliferation. As such, synthetic small‐molecule repressors (inverse agonists) targeting RORγ have been extensively studied for their potential as therapeutic agents for various autoimmune diseases. Alternatively, enhancing T_H17 cell proliferation through activation (agonism) of RORγ may boost an immune response, thereby offering a potentially new approach in cancer immunotherapy. Herein we describe the development of N‐arylsulfonyl indolines as RORγ agonists. Structure–activity studies reveal a critical linker region in these molecules as the major determinant for agonism. Hydrogen/deuterium exchange coupled to mass spectrometry (HDX‐MS) analysis of RORγ–ligand complexes help rationalize the observed results.     

Conservative Polarimetric Scatterers and Their Role in Incorrect Extensions of the Cameron Decomposition

The properties of conservative symmetric polarimetric scatterer scattering matrices are examined. It is shown that the unambiguous rotation angle for "conservative" symmetric polarimetric scatterers is the interval (-pi/4,+pi/4] as compared with (-pi/2,+pi/2] for nonconservative symmetric scatterers. Errors relating to the Cameron decomposition, which are recently introduced into the literature, are discussed. It is demonstrated that these errors arise from a faulty symmetric scatterer scattering matrix distance measure. This, in turn, leads to an improper mapping of the symmetric scatterer unit disk to a hemisphere. The correct mapping of the symmetric scatterer unit disk to the symmetric scatterer unit sphere is described     

A comparison of lead isotope ratios in the bark pockets and annual rings of two beech trees collected in Derbyshire and South Yorkshire, UK

ICP-MS analysis of the bark pockets and annual rings of two beech (Fagus sylvatica L.) trees collected from Longshaw, Derbyshire and Swinton, South Yorkshire in the UK recorded differences in the (206)Pb/(207)Pb isotope ratio. In the Longshaw sample, the (206)Pb/(207)Pb isotope ratio of the bark pockets ( approximately 1914-1998, 78-260 microg g(-1) Pb) declined from approximately 1.16 to 1.12, whilst the annual rings (1899-1998, 0.2-2.5 microg g(-1) Pb) had a (206)Pb/(207)Pb ratio of approximately 1.18. In the Swinton sample, the bark pockets (approximately 1919-1998, 7-78 microg g(-1) Pb) declined from 1.15 to 1.11 and the annual rings (1899-1998, 0.2-0.5 microg g(-1) Pb) from 1.18 to 1.15. The data implied that the bark pockets accumulated lead directly from the atmosphere through wet and dry deposition, whilst the annual rings accumulated lead from the soil via the roots. The bark pockets recorded a relative decline in the accumulation of lead from indigenous sources, such as lead smelting and coal combustion (1.17-1.19), and increase in imported sources such as the smelting of Australian ores (1.04) and leaded petrol usage (1.06-1.09). In contrast, the annual rings at Longshaw recorded ratios typical of indigenous lead, whilst the annual rings in Swinton recorded a relatively small decrease in (206)Pb/(207)Pb reflecting leaded petrol usage. The decline in (206)Pb/(207)Pb of the bark pockets was consistent with the historical decline in (206)Pb/(207)Pb of atmospheric lead recorded in peat, lake sediments and archival herbage at other UK locations.