Inequity in equity: How "equity" can lead to inequity for high-potential students.

Over the past three decades, the achievement of waves of American students with high intellectual potential has declined as a result of inequity in educational treatment. This inequity is the result of an extreme form of egalitarianism within American society and schools, which involves the pitting of equity against excellence rather than promoting both equity and excellence, anti-intellectualism, the "dumbing down" of the curriculum, equating aptitude and achievement testing with elitism, the attraction to fads by schools, and the insistence of schools to teach all students from the same curriculum at the same level. In this article we provide recommendations for creating positive change--recommendations that emphasize excellence for all, that call for responsiveness to individual differences, and that suggest basing educational policies on well-grounded research findings in psychology and education. Educational policies that fail to take into account the vast range of individual differences among students--as do many that are currently in us--are doomed to be ineffective. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Selective CO-oxidation over Ru-based catalysts in H2-rich gas for fuel cell applications

Topics in Catalysis - Ru-based catalysts supported on A zeolites and alumina were synthesised, characterised (XRD, SEM-EDS, TPR) and tested under realistic conditions for the preferential oxidation...     

Issues and Implications of Deaf Culture in Therapy.

In the United States, it is estimated that between 200,000 and 500,000 individuals are culturally Deaf. Deaf culture provides unique challenges that can impact standard therapeutic techniques. Issues regarding the ability of hearing therapists to effectively work with Deaf clients are addressed, and a number of guidelines are offered to assist hearing therapists in bridging language barriers and cultural gaps with Deaf clients. Additionally, concerns about the selection and inclusion of sign language interpreters are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Embedding deductive capabilities in relational database systems

The basic idea of our work is to include deductive capabilities in a relational database system by fully using the operands of relational algebra and without using any theorem prover. We present a deductive database system where the user can formulate deduction laws as logical formulas, but which works on an underlying relational database system by fully using the data manipulation routines of such a system. Generally, it is not possible to express the deduction laws by means of expressions of relational algebra (see Ref. 1). In our system, a relational algebra expression is associated with every database deduction law. The result of its evaluation (with respect to an underlying database) is the set of all database entries that can be deduced from the database by applying the respective law once (Theorem 1). By successively applying all these relational expressions for all the database deduction laws it is possible to generate the whole extensional database (i.e. all tuples deducible from the database).     

Adsorption of antifouling booster biocides on metal oxide nanoparticles: Effect of different metal oxides and solvents

Controlling the release rate of biocides (antifouling agents) from a paint coating is a key issue for the development of multi-season antifouling marine coatings. One promising approach is the use of nanoparticles onto which biocides are adsorbed to prevent premature depletion of the biocide. Adsorption of one novel (Medetomidine) and six commercially available and widely used antifouling biocides (Chlorothalonile, Dichlofluanid, Diuron, Irgarol, Seanine, Tolylfluanid) onto oxide nanoparticles (Al₂O₃, CuO, MgO, SiO₂, TiO₂, ZnO) was investigated by HPLC and NMR in different organic solvents. Large differences in adsorption strength depending on the type of nanoparticle and solvent employed were observed. It was shown that nanoparticles coordinate preferentially with the imidazole moiety of Medetomidine. Independent of the type of particle this interaction was considerably stronger in comparison to the other biocides. However, the interaction strength was strongly dependant on the type of solvent, where the largest strongest interaction was achieved in o-xylene. In addition field tests were performed where a considerable decrease in release rate was displayed from coatings containing Medetomidine adsorbed to nanoparticles compared to coatings containing Medetomidine as single additive.     

Optimisation of enzymatic hydrolysis for concentration of squalene in palm fatty acid distillate

BACKGROUND: Squalene was concentrated from palm fatty acid distillate (PFAD) in this study using commercial immobilised Candida antarctica lipase (Novozyme 435^®). The PFAD was neutralised (NPFAD) using an alkali to liberate the free fatty acids and then hydrolysed at 65 ± 1 °C. The enzymatic hydrolysis on NPFAD was optimised using response surface methodology (RSM) before being neutralised again to obtain a concentrated squalene fraction. RESULTS: A five‐level, three‐factor central composite rotatable design was adopted to evaluate the effects of the enzymatic hydrolysis parameters reaction time (4–12 h), water content (50–70% w/w) and enzyme concentration (1.5–3.5% w/w) on the percentage yield of squalene concentration. The optimal reaction parameters for maximum yield of squalene concentration were identified from the respective contour plots. The optimal enzymatic hydrolysis conditions were a reaction time of 7.05 h, a water content of 61.40% w/w and an enzyme concentration of 2.23% w/w. CONCLUSION: RSM was used to determine the optimal conditions for enzymatic hydrolysis of NPFAD with C. antarctica lipase for maximum recovery of squalene which could be implemented on an industrial scale. Copyright © 2008 Society of Chemical Industry     

1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells,Targeting GSK3β Kinase

A new series of topsentin analogs, in which the central imidazole ring of the natural lead was replaced by a 1,2,4-oxadiazole moiety, was efficiently synthesized. All derivatives were pre-screened for antiproliferative activity against the National Cancer Institute (NCI-60) cell lines panel. The five most potent compounds were further investigated in various pancreatic ductal adenocarcinoma (PDAC) cell lines, including SUIT-2, Capan-1, and Panc-1 cells, eliciting EC₅₀ values in the micromolar and sub-micromolar range, associated with significant reduction of cell migration. These remarkable results might be explained by the effects of these new topsentin analogues on epithelial-to-mesenchymal transition markers, including SNAIL-1/2 and metalloproteinase-9. Moreover, flow cytometric analysis after Annexin V-FITC and propidium iodide staining demonstrated that these derivatives enhanced apoptosis of PDAC cells. Keeping with these data, the PathScan intracellular signaling and ELISA array revealed cleavage of caspase-3 and PARP and a significant inhibition of GSK3β phosphorylation, suggesting this kinase as a potential downstream target of our novel compounds. This was further supported by a specific assay for the evaluation of GSK3β activity, showing IC₅₀ values for the most active compounds against this enzyme in the micromolar range.     

Correction to: Online Identity Crisis: Identity Issues in Online Communities

Minds and Machines - An amendment to this paper has been published and can be accessed via the original article.