Potential of near infrared spectroscopy to assess hot-water-soluble extractive content and decay resistance of a tropical hardwood

The ability to identify both low- and high-durability samples in a population of naturally durable samples would allow more rational use of these materials, for example, using samples in the lower ranges of durability in non-soil contact. One possible method for rapidly assessing differences in heartwood characteristics related to durability is near infrared spectroscopy (NIR) coupled with multivariate statistical methods. A number of recent studies suggest that NIR can be related to a variety of wood properties, including extractive content. There are, however, few data on the ability of this technique to assess decay resistance, especially in hardwoods or species with high natural durability. In this report, the ability of NIR to predict both extractive content and resistance to fungal attack in Goncalo alves (Astronium graveolens) was assessed. NIR spectra accurately predicted hot-water-soluble extractive content of A. graveolens and its susceptibility to the white rot fungus Trametes versicolor. A. graveolens was very resistant to attack by the brown rot fungus Gloeophyllum trabeum and NIR spectra were not useful predictors of weight loss. NIR spectroscopy may be a useful tool for rapidly assessing the extractive content and decay resistance of naturally durable wood.     

The synthesis and characterization of copper-based metal–organic framework/graphite oxide composites

New composites of a copper-based metal–organic framework and graphite oxide were synthesized with different ratios of HKUST-1 (also called MOF-199) and graphite oxide. These compounds, as well as the parent materials, were characterized by X-ray diffraction, sorption of nitrogen, FT-IR spectroscopy, thermal analyses, scanning electron microscopy, and sorption of hydrogen. The composites exhibit features similar to HKUST-1 as well as an increased porosity compared to the parent materials. The formation of new small pores is demonstrated by an increase in the hydrogen uptake. The results suggest that the building process of the composites occurs via the reaction/binding of the copper dimers from the HKUST-1 with/to the functional groups in graphite oxide (epoxy, carboxylic, hydroxylic, sulfonic).     

Adapting the French nuclear fleet to integrate variable renewable energies via the production of hydrogen: Towards massive production of low carbon hydrogen?

Producing low-carbon hydrogen at a competitive rate is becoming a new challenge with respect to efforts to reduce greenhouse gas emissions. We examine this issue in the French context, which is characterised by a high nuclear share and the target to increase variable renewables by 2050. The goal is to evaluate the extent to which excess nuclear power could contribute to producing low-carbon hydrogen.Our approach involves designing scenarios for nuclear and renewables, modelling and evaluating the potential nuclear hydrogen production volumes and costs, examining the latter through the scope of hydrogen market attractiveness and evaluating the potential of CO₂ mitigation.This article shows that as renewable shares increase, along with the hydrogen market expected growth driven by mobility uses, opportunities are created for the nuclear operator. If nuclear capacities are maintained, nuclear hydrogen production could correspond to the demand by 2030. If not, possibilities could still exist by 2050.     

Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice

Mucosal CD4⁺ T lymphocytes display a potent opioid-mediated analgesic activity in interleukin (IL)-10 knockout mouse model of inflammatory bowel diseases (IBD). Considering that endogenous opioids may also exhibit anti-inflammatory activities in the periphery, we examined the consequences of a peripheral opioid receptor blockade by naloxone-methiodide, a general opioid receptor antagonist unable to cross the blood–brain barrier, on the development of piroxicam-accelerated colitis in IL-10-deficient (IL-10^-/-) mice. Here, we show that IL-10-deficient mice treated with piroxicam exhibited significant alterations of the intestinal barrier function, including permeability, inflammation-related bioactive lipid mediators, and mucosal CD4⁺ T lymphocyte subsets. Opioid receptor antagonization in the periphery had virtually no effect on colitis severity but significantly worsened epithelial cell apoptosis and intestinal permeability. Thus, although the endogenous opioid tone is not sufficient to reduce the severity of colitis significantly, it substantially contributes to the protection of the physical integrity of the epithelial barrier.     

A pilot scale study of reverse osmosis for the purification of condensate arising from distillery stillage concentration plant

Reverse osmosis (RO) is an interesting process to eliminate small organic solutes (carboxylic acids and alcohols) from distillery condensates before recycling them into the fermentation step. This work investigates the influence of transmembrane pressure, pH and volume reduction factor (VRF) on the efficiency of reverse osmosis treatment of condensate from distillery stillage concentration at pilot scale using three pre-selected membranes (CPA2 and ESPA2 from Hydranautics, BW30 from DOW). Performances were assessed according to permeate flux, solutes rejection and abatement of fermentation inhibition. Transmembrane pressure increase leads to an increase of these three parameters with a plateau for rejections and abatement at 20 bar; however, in order to comply with membranes manufacturer's recommendations and to limit or delay polarization and fouling, it was decided to keep the permeate flux below a value of 30 L h⁻¹ m⁻². This corresponded to a maximum pressure of 10 bar for CPA2 and ESPA2 membranes and 25 bar for BW30 membrane. pH increase leads to a diminution of permeate flux and an increase of carboxylic acids rejection whatever the membrane; nevertheless, no abatement of fermentation inhibition is observed. Increasing VRF provokes a decrease of the permeate flux. Although local rejections are stable, the mean rejection assessed with the raw condensate (feed) and the mean permeate decreases. However, the fermentation inhibition remains under 10% up to a VRF of 8. BW30 membrane exhibits the highest rejections and inhibition abatement. On the basis of the pilot scale results with the BW30 membrane, a preliminary estimation of the membrane area is proposed for an industrial plant with 100 m³ h⁻¹ of condensate flow rate and the optimized parameters (pressure 25 bar, no pH modification, VRF 4 and 8).     

Comparison between electrocoagulation and chemical precipitation for metals removal from acidic soil leachate

This paper provides a quantitative comparison between electrocoagulation and chemical precipitation based on heavy metals (Cd, Cr, Cu, Ni, Pb and Zn) removal from acidic soil leachate (ASL) at the laboratory pilot scale. Chemical precipitation was evaluated using either calcium hydroxide or sodium hydroxide, whereas electrocoagulation was evaluated via an electrolytic cell using mild steel electrodes. Chemical precipitation was as effective as electrocoagulation in removing metals from ASL having low contamination levels (30 mg Pbl(-1) and 18 mg Znl(-1)). For ASL enriched with different metals (each concentration of metals was initially adjusted to 100 mg l(-1)), the residual Cr, Cu, Pb and Zn concentrations at the end of the experiments were below the acceptable level recommended for discharge in sewage urban works (more than 99.8% of metal was removed) using either electrocoagulation or chemical precipitation. Cd was more effectively removed by electrochemical treatment, whereas Ni was easily removed by chemical treatment. The cost for energy, chemicals and disposal of metallic residue of electrocoagulation process ranged from USD 8.83 to 13.95 tds(-1), which was up to five times lower than that recorded using chemical precipitation. Highly effective electrocoagulation was observed as the ASL was specifically enriched with high concentration of Pb (250-2000 mg Pbl(-1)). More than 99.5% of Pb was removed regardless of the initial Pb concentration imposed in ASL and, in all cases, the residual Pb concentrations (0.0-1.44 mg l(-1)) were below the limiting value (2.0 mg l(-1)) for effluent discharge in sewage works.     

An accurate real-time PCR test for the detection and quantification of cauliflower mosaïc virus (CaMV): applicable in GMO screening

Maher Chaouachi and Marie Noelle Fortabat are contributed equally to this work.     

Bipartite modular multiplication with twice the bit-length of multipliers

This paper presents a new technique to compute 2ℓ-bit bipartite multiplications with ℓ-bit bipartite multiplication units. Low-end devices such as smartcards are usually equipped with crypto-coprocessors for accelerating the heavy computation of modular multiplications; however, security standards such as NIST and EMV have declared extending the bit length of RSA cryptosystem to resist mathematical attacks, making the multiplier quickly outdated. Therefore, the double-size techniques have been studied this decade to extend the life expectancy of such multipliers. This paper proposes new double-size techniques based on the multipliers implementing either classical or Montgomery modular multiplications, or even both simultaneously (bipartite modular multiplication), in which case one can potentially compute modular multiplications twice faster. Furthermore, in order to get a more realistic estimation than the other works, this paper considers not only the cost of the multiplication, but also the cost of the other arithmetic instructions. In our estimation, the proposal provides comparable results for classical multiplier and Montgomery multiplier, and is the only available method for the bipartite multiplier. A preliminary version of this paper was presented at the 12th Australasian Conference on Information Security and Privacy, ACISP’07.     

Plasticized P(VDF-TrFE): A new flexible piezoelectric material with an easier polarization process,promising for biomedical applications

In this work, flexible ferroelectric films of P(VDF-TrFE) softened by a plasticizer are elaborated. Morphology, piezoelectric, mechanical, thermal, and crystalline properties of the films are studied. We show that the elastic constant is reduced up to 30% while increasing the remanent polarization and the piezoelectric coefficient thanks to the lubricant property of the plasticizer, helping the orientation of the crystallites. Plus, the decrease of the coercive field from 46 to 32 V/μm after an annealing at 138°C for a plasticizer content ranging between 20 and 50 wt% is observed and an explanation by based on a polymer/plasticizer demixing is provided. It leads to an easier polarization process with a significant saving in time and applied electric field reducing the breakdown voltage. Both effects could be interesting for an industrial production. Finally, a first sensor is elaborated and characterized electrically with homemade test bench. We show that the softening of the P(VDF-TrFE) offers to the device a larger amplitude range of deformations. The combination of the flexibility with high ferroelectric properties of the plasticized P(VDF-TrFE) make it a very promising material for biomedical sensor applications.     

The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes

Bone metastasis remains the most frequent and the deadliest complication of prostate cancer (PCa). Mechanisms leading to the homing of tumor cells to bone remain poorly characterized. Role of chemokines in providing navigational cues to migrating cancer cells bearing specific receptors is well established. Bone is an adipocyte-rich organ since 50 to 70% of the adult bone marrow (BM) volume comprise bone marrow adipocytes (BM-Ads), which are likely to produce chemokines within the bone microenvironment. Using in vitro migration assays, we demonstrated that soluble factors released by human primary BM-Ads are able to support the directed migration of PCa cells in a CCR3-dependent manner. In addition, we showed that CCL7, a chemokine previously involved in the CCR3-dependent migration of PCa cells outside of the prostate gland, is released by human BM-Ads. These effects are amplified by obesity and ageing, two clinical conditions known to promote aggressive and metastatic PCa. In human tumors, we found an enrichment of CCR3 in bone metastasis vs. primary tumors at mRNA levels using Oncomine microarray database. In addition, immunohistochemistry experiments demonstrated overexpression of CCR3 in bone versus visceral metastases. These results underline the potential importance of BM-Ads in the bone metastatic process and imply a CCR3/CCL7 axis whose pharmacological interest needs to be evaluated.