In vivo purging with high-dose cytarabine followed by high-dose chemoradiotherapy and reinfusion of unpurged bone marrow for adult acute myelogenous leukemia in first complete remission

PURPOSE: To evaluate in a prospective study the efficacy of autologous bone marrow transplantation (BMT) in adult patients with acute myelogenous leukemia (AML) in first remission, using a single course of high-dose Cytarabine (HD Ara-C) consolidation therapy as in vivo purging. PATIENTS AND METHODS: Sixty consecutive adult patients with AML in first complete remission (CR) were treated with HD Ara-C consolidation therapy as a method of in vivo purging before marrow collection. High-dose therapy consisted of fractionated total-body irradiation (FTBI) 12 Gy, intravenous etoposide 60 mg/kg, and cyclophosphamide 75 mg/kg, followed by reinfusion of cryopreserved marrow. RESULTS: Sixty patients underwent consolidation treatment with HD Ara-C with the intent to treat with autologous BMT. Sixteen patients were unable to proceed to autologous BMT (10 patients relapsed, one died of sepsis, one developed cerebellar toxicity, two had inadequate blood counts, and two refused). Forty-four patients underwent autologous BMT and have a median follow-up time of 37 months (range, 14.7 to 68.7) for patients who are alive with no relapse. The cumulative probability of disease-free survival (DFS) at 24 months in the intent-to-treat group is 49% (95% confidence interval [CI], 37% to 62%) and in those who actually underwent autologous BMT is 61% (95% CI, 46% to 74%). The probability of relapse was 44% (95% CI, 31% to 58%) and 33% (95% CI, 20% to 49%) for the intent-to-treat and autologous BMT patients, respectively. CONCLUSION: This approach offers a relatively high DFS rate to adult patients with AML in first CR. The results of this study are similar to those achieved with allogeneic BMT.     

A variational method for contour tracking via covariance matching

This paper presents a novel formulation for contour tracking.We model the second-order statistics of image regions and perform covariance matching under the variational level set framework.Specifically,covariance matrix is adopted as a visual object representation for partial differential equation(PDE) based contour tracking.Log-Euclidean calculus is used as a covariance distance metric instead of Euclidean distance which is unsuitable for measuring the similarities between covariance matrices,because the matrices typically lie on a non-Euclidean manifold.A novel image energy functional is formulated by minimizing the distance metric between the candidate object region and a given template,and maximizing the one between the background region and the template.The corresponding gradient flow is then derived according to a variational approach,enabling partial differential equations(PDEs) based contour tracking.Experiments on several challenging sequences prove the validity of the proposed method.     

24m~2烧结机自动化改造方案

介绍烧结机不停产自动化改造的方法,阐述构成工艺过程控制的DCS系统组合以及变频调速技术改造电磁滑差调速成功的选型方法。     

电视监控系统云台控制器设计

电视监控系统是一种典型的分布式计算机信号采集系统。为了提高监控的范围和效果,云台控制器的优劣直接影响监控的范围和效果,因此对云台控制器的设计具有重要的意义。本系统采用串型通信,通过Modbus协议把控制信号输入单片机,经过对AT89S52单片机的编程,从而对八路继电器输出进行控制。系统不仅结构简单,而且还可以方便的对镜头、防护罩的控制进行扩展,功能强大,可以广泛应用于电视监控系统中的云台控制。     

松材线虫病害高光谱时序与敏感特征研究

采用高光谱仪ASD FieldSpec Pro FR,连续观测了健康和发病马尾松针叶的时序高光谱,分析了松材线虫病害光谱的时序特征、敏感时期和敏感特征。结果表明:与健康马尾松相比,病害马尾松时序光谱差异较大;病害首先造成红边区域内光谱反射率减低,然后再出现红边蓝移的2阶段光谱变化规律;感染松材线虫的马尾松9月初已经出现了病态植被典型的光谱特征;近红外平台内最大的一阶微分值、红边内一阶微分的总和(SDr)与蓝边内一阶微分的总和(SDb)的比值等是指示病害发生的显著性高光谱特征。     

Hadoop在VOD系统中的应用研究

首先对当前VOD系统进行简单介绍,指出当前VOD系统存储架构的不足,接着介绍Hadoop,分析HDFS的存储机制和特点,指出将HDFS用于存储视频文件的优势。通过将Hadoop和当前VOD系统融合,提出基于Hadoop的VOD原型系统设计方案。最后总结将Hadoop用于VOD系统的优势,给出进一步研究计划。     

Image cipher using image filtering with 3D DNA-based confusion and diffusion strategy

Neural Computing and Applications - In this paper, an image cipher is presented based on DNA sequence operations, image filtering and memrisitve chaotic system. Firstly, plain image is preprocessed...     

Exploiting 2D compressed sensing and information entropy for secure color image compression and encryption

Neural Computing and Applications - Compared to 1D compressed sensing (CS), 2D CS is more efficient for compressing the plaintext image from two directions, but security level of current 2D...     

煤矿带式输送机监控软件的设计

采用VB6.0设计了一套煤矿带式输送机监控软件,介绍了软件总体设计及实时监控主画面设计方案,阐述了采用MSComm控件、Winsock控件分别实现上下位机的串口通信、以太网通信的方法。该监控软件画面直观,控制灵活,较为实用。     

一种新型吊舱推进自航试验测控技术

设计了一种新型的应用于吊舱推进自航试验的测控系统;进一步缩小吊舱动力仪的尺寸,该套测控系统将扭矩传感器放置在电机输出端,从而避免了因船模尺寸过大而带来的一系列试验问题;该测控系统分为吊舱单元驱动程序和吊舱水动力信号采集程序两个软硬件模块,采用MODBUS通信协议控制伺服电机转动,实现了双吊舱推进器之间的转速同步;采用NI公司的LabVIEW进行软件开发;在对某海洋工程船进行吊舱推进器自航试验中使用了该测控系统,试验得到实船自航因子及收到功率等参数.