A high-throughput chaotic advection microreactor for preparation of uniform and aggregated barium sulfate nanoparticles

A high-throughput (105.5 g/h) passive four-stage asymmetric oscillating feedback microreactor using chaotic mixing mechanism was developed to prepare aggregated Barium sulfate (BaSO₄) particles of high primary nanoparticle size uniformity. Three-dimensional unsteady simulations showed that chaotic mixing could be induced by three unique secondary flows (i.e., vortex, recirculation, and oscillation), and the fluid oscillation mechanism was examined in detail. Simulations and Villermaux–Dushman experiments indicate that almost complete mixing down to molecular level can be achieved and the prepared BaSO₄ nanoparticles were with narrow primary particle size distribution (PSD) having geometric standard deviation, σ_g, less than 1.43 when the total volumetric flow rate Q_total was larger than 10 ml/min. By selecting Q_total and reactant concentrations, average primary particle size can be controlled from 23 to 109 nm as determined by microscopy. An average size of 26 nm with narrow primary PSD (σ_g = 1.22) could be achieved at Q_total of 160 ml/min.     

Physiologically based pharmacokinetic models of 2'',3''-dideoxyinosine

In this paper, the construction, evaluation, and application of cDNA libraries from eight unfertilized oocytes and single four-cell-, seven-cell-, and blastocyst-stage embryos are described. Rapid, reproducible, and efficient procedures for the construction of PCR-based cDNA libraries from fewer than 10 cells were first developed in small populations of fibroblast cells. The human embryo libraries display complexities sufficient (between 10(5) and 10(6) clones) to represent the entire active gene population at these early stages of human development. The ubiquitous cytoskeletal elements, beta-actin, keratin-18, and alpha-tubulin, were detected at the expected frequency. Sequencing of consecutively picked random clones, without selection, showed the presence of a variety of sequences, such as the human transposable element, LINE-1 and Alu repeat sequences, housekeeping genes, and tissue-specific genes, such as alpha-globin and FMR-1. In addition to cDNAs corresponding to known ESTs (expressed sequence tags) in the GenBank and dbEST databases, a high proportion of novel sequences were detected. Applications of the libraries to several areas of interest, such as expression of CpG-island-containing "tissue-specific" genes, developmental genes expressed in a stage-specific manner, and a search for monoallelic expression of imprinted genes, are described. The libraries are a valuable resource for the study of gene expression during human preimplantation development and obviate the need for research on the human embryos themselves.     

All‐Cellulose‐Based Quasi‐Solid‐State Sodium‐Ion Hybrid Capacitors Enabled by Structural Hierarchy

Na‐ion hybrid capacitors consisting of battery‐type anodes and capacitor‐style cathodes are attracting increasing attention on account of the abundance of sodium‐based resources as well as the potential to bridge the gap between batteries (high energy) and supercapacitors (high power). Herein, hierarchically structured carbon materials inspired by multiscale building units of cellulose from nature are assembled with cellulose‐based gel electrolytes into Na‐ion capacitors. Nonporous hard carbon anodes are obtained through the direct thermal pyrolysis of cellulose nanocrystals. Nitrogen‐doped carbon cathodes with a coral‐like hierarchically porous architecture are prepared via hydrothermal carbonization and activation of cellulose microfibrils. The reversible charge capacity of the anode is 256.9 mAh g^?1 when operating at 0.1 A g^?1 from 0 to 1.5 V versus Na⁺/Na, and the discharge capacitance of cathodes tested within 1.5 to 4.2 V versus Na⁺/Na is 212.4 F g^?1 at 0.1 A g^?1. Utilizing Na⁺ and ClO₄^? as charge carriers, the energy density of the full Na‐ion capacitor with two asymmetric carbon electrodes can reach 181 Wh kg^?1 at 250 W kg^?1, which is one of the highest energy devices reported until now. Combined with macrocellulose‐based gel electrolytes, all‐cellulose‐based quasi‐solid‐state devices are demonstrated possessing additional advantages in terms of overall sustainability.     

Methane Aromatization over 2 wt% Mo/HZSM-5 in the Presence of O2 and NO

In the non-oxidative aromatization reaction (temperature = 770 C, flow rate = 34 ml min^-1), 2 wt% Mo/HZSM-5 deactivated after 4 h due to severe coking. We observed that with a suitable amount of O₂ (5.3 vol%) in the methane feed, the catalyst could last for more than 6 h with a ca. 4% yield of aromatics at 770 °C. Depending on the concentration of O₂ or the reaction temperature, there are three reaction zones in the catalyst bed: (i) methane oxidation; (ii) methane reforming; and (iii) methane aromatization. CO and H₂ produced in the first two zones are accountable for stability amelioration of the catalyst. The addition of NO exhibited similar effects on the reaction. Further increase in O₂ (8.4 vol%) or NO (14.2 vol%) concentration would result in CO and CO₂ being the predominant carbon-containing products; C₂H₄ and C₂H₆ were generated in small amounts and no aromatics were detected.     

Vibration analysis of rectangular Mindlin plates with internal line supports using static Timoshenko beam functions

In this paper, the vibration characteristics of rectangular Mindlin plates with internal line supports in one or two directions are studied by using the Rayleigh–Ritz method. The static Timoshenko beam functions are employed as admissible functions, which are composed of a set of transverse deflection functions and a set of rotation-angle functions due to bending. The static Timoshenko beam functions are derived from a point-supported strip of unit width taken from the particular plate under consideration in a direction parallel to the edge of the plate and acted upon by a series of static sinusoidal loads distributed along the length of the strip. It can be seen that the suggested approach is very simple mathematically, and each of the beam functions is only a sine or cosine function plus a polynomial function of not more than the third order. A unified program can be easily prepared, because the changes in boundary conditions, number and locations of internal line supports and thickness ratio of the plate will result in a corresponding change of only the coefficients of the polynomials. Both high accuracy and low computational cost have been verified by convergence and comparison studies. In addition, it can be seen that the admissible functions presented in this paper can also properly describe the discontinuity conditions of the shear forces at the line supports. Therefore, accurate results can be expected for the analysis of dynamic response and internal force distribution of the plate.     

Decision model for country site selection of overseas clothing plants

Clothing manufacturers’ direct investment and joint ventures in developing regions have grown rapidly in the last few decades. An inappropriate decision on site selection can cause adverse affects on productivity and increase manufacturing and logistical costs. Manufacturers often face with difficulties during the decision-making process, due to vague and subjective considerations. The process is hampered with variables that cannot be represented in terms of objective values, such as country risk and community facilities. The decision on plant location thus relies mostly on the subjective intuition and assessment of the manufacturer. This paper explains the development of a decision-making model for a clothing plant location, using the feed-forward neural network with an error back-propagation (EBP) learning algorithm and a fuzzy analytical hierarchy process (FAHP). Significant variables in the selection of a clothing plant location will be identified and input into the proposed decision-making model. A suitability index was computed for each site. The sites with higher suitability indices were more appropriate for the establishment of a clothing plant. It was also identified that those variables considered on plant location with lower evaluation weights can be neglected without affecting the prediction accuracy of the proposed decision model .     

Relationship between Organizational Sizes and Contractors’ Risk Pricing Behaviors for Weather Risk under Different Project Values and Durations

A problem that always annoys building employers and their consultants when drafting building contracts is whether it is more cost efficient to retain certain risks with themselves or to transfer the same to contractors, and it has long been a difficulty to accurately estimate the cost for transferring risks to the other contract party. It is a very common market practice to remove contractors’ entitlement to extension of time due to inclement weather, and in view of the significant impacts that inclement weather posed on construction progress, it would be helpful to assess the associated costs for such risk allocation exercises in order to ensure that it is a cost-effective transaction. The costs for these potential weather-caused delays are priced by contractors in their returned tenders. This risk-pricing behavior is affected by the contractor’s risk perception and risk attitude. However, merely working out contractors’ risk perception and risk attitude patterns is inadequate, as they may vary in accordance with different organizational sizes and project backgrounds. Therefore, further studies should be carried out on the implications of project information, such as project value and contract period, on different-sized contractors’ risk behaviors. In this research, a questionnaire survey was conducted to investigate the weather-risk-pricing behavioral patterns of various-sized contractors under different given project scenarios. The survey revealed that the impacts of project value and contract period (and, thus, the intensity of work and scale of exposure to weather risk) were significant on contractors’ risk behaviors, and these impacts varied in accordance with different organizational sizes. The medium-sized contractors’ pricing behaviors were rather constant under different project values and contract periods, while both small and large contractors behaved differently when the intensity of work and scale of risk exposure varied. Despite the fact that contractors of various sizes behaved differently in some given scenarios, the number of days of delaying cost allowed by them in returned tenders were generally less than the actual number of days of inclement weather affecting work.     

Theoretical and experimental studies of a microstrip antenna with two parasitic patches

The variations of the dimensions and locations of two stacked parasitic elements on the input impedance SWR bandwidth and radiation patterns of aperture-coupled rectangular microstrip antennas are analyzed. It is found that the SWR bandwidth can be improved by selecting appropriate sizes and locations of the parasitic patches. A 45% bandwidth of patch antennas was attained for SWR≤2.2. Experimental results are obtained to verify the theory. © 1998 John Wiley & Sons, Inc. Int J RF and Microwave CAE 8: 49–55, 1998.