Finite element program for moisture and heat transfer in heated concrete

A new axisymmetric finite element program for the analysis of pore pressure, moisture content and temperature in heated concrete is described. The program is based on the diffusion equations for coupled heat and moisture transfer and uses a step-by-step time integration. The finite element scheme is based on Galerkin method. For time integration a step-by-step solution with iterations is used. The numerical analysis is complicated by the fact that the sorption isotherms exhibit a steep jump at saturation-nonsaturation transitions, and that the permeability dependence on temperature exhibits a jump of two orders of magnitude at 100°C. The mathematical model takes into account the release of chemically bound water due to dehydration and the associated changes in the pore space. The program may also be used at normal temperatures. Predictions of the program are compared with tests by HEDL as well as two other existing programs.     

Plasma insulin levels in coronary artery disease

Seventy two consecutive patients without a history of diabetes and normal fasting plasma glucose were included in this study of insulin levels. Standard oral glucose tolerance test with 75 gm glucose and fasting and two hour insulin levels were estimated in all patients. Coronary artery disease (CAD) was confirmed or excluded by selective coronary arteriography. In 20 patients, CAD was diagnosed by electrocardiographic (ECG) and clinical evidence of earlier myocardial infarction. Mean fasting plasma insulin was 31.40 +/- 22.2 IU/dl in the CAD positive and 32.3 +/- 13.6 IU/dl in the CAD negative group. The mean two hour plasma insulin was 274.6 +/- 301.1 IU/dl in the CAD positive and 104.8 +/- 74.9 IU/dl in the CAD negative group (p < 0.04). Two hour plasma insulin levels were significantly higher in patients with atherosclerotic coronary artery disease. It is concluded that the estimation of a two hour plasma insulin level after 75 gm of glucose load, could help differentiate CAD from normals.     

Developmental toxicity of 1,2-dichloropropane (PDC) in rats and rabbits following oral gavage

The ST-16 antigenic specificity of the HLA-B locus is defined as a B39 variant of Mexican-Americans. Nucleotide sequencing of cDNA shows the ST-16 allele (B*3905) differs from B*39011 by a single substitution that substitutes tyrosine for aspartic acid at position 74 of the mature class I heavy chain. The complete coding region sequence for the common caucasoid allele encoding the B38 antigen has been determined. This B*3801 allele differs from B*3802 at two nucleotide substitutions within the Bw4 sequence motif. B*3801 and B*3802 may have been derived independently from B*39011 by conversion events with B alleles donating distinctive Bw4 motifs. A novel allele B*39022 derived from a Colombian Indian differs from the B*39021 allele of Japanese origin at two widely separated silent substitutions. Comparison of sequences for the known B16 alleles suggest that B*39021 and B*39022 were independently derived by recombination from B*39013 and B*39011 respectively.     

Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study

Normal women produce small amounts of active androgens. When androgen levels are elevated, such as for example in the polycystic ovary syndrome, this is followed by the development of male physical characteristics and muscle mass, structure and function as well as android adipose tissue distribution and function. Psychological features and stress reactions also seem similar to those of men. Such women have an increased risk of developing hypertension, non-insulin-dependent diabetes mellitus and cardiovascular disease. Recent data have shown that these physical, and psychological characteristics, as well as risk of ill health, are also found in the population of women selected at random. Women in the lowest quintiles of levels of sex-hormone-binding globulin--an indicator inversely related to active androgens--are at risk of developing hypertension, non-insulin-dependent diabetes mellitus and cardiovascular mortality. The mechanism probably includes muscular insulin resistance, following a relative androgen excess. It is thus apparent that androgens, even within the highest levels of the nonselected population of women, are powerful predictors of serious disease development. The population at risk might be as large as about 20% of middle-aged women. This is an area of female disease risk which requires more attention in screening and intervention procedures.     

How does Internet information seeking help academic performance? – The moderating and mediating roles of academic self-efficacy

Although researchers tend to agree that Internet is a good source for learning and research, little empirical data has substantiated this claim by specifically linking time and effort spent on the Internet for school related information seeking to academic performances. This research investigates the relationship between vocational high school students’ information seeking activities on the Internet, academic self-efficacy, and academic performance. We propose that academic self-efficacy both mediates and moderates the relationship between Internet information seeking and academic performance. Using survey data from 295 vocational high school students in Taiwan, we found that the positive effect of Internet information seeking to students’ academic performance is mediated through academic self-efficacy. Academic self-efficacy, at the same time, moderates the relationship between Internet information seeking to academic performance such that students’ with low academic self-efficacy benefit more from Internet information seeking in regard to their academic performance. We discussed the implications of our findings and provided future directions for research.     

Assessing the efficiency of supply chain scheduling algorithms using data envelopment analysis

Where different supply chain planning algorithms are used, generally similar results may pose some challenges on the differentiating powers of evaluating different production schedules because of the increasing complexity of a supply chain network structure. For the comparison purpose, performance evaluation of different supply chain planning algorithms aims to use different supply chains models with different demands, capacities, and commonality through efficiency perspective by using a modified network rational data envelopment analysis (DEA) model. The proposed DEA model has the abilities: (1) to treat only undesirable outputs that exist without normal output, and the situation where input and output are both zero by introducing two new parameters to denote the maximum inventory and amount of delayed demands of a given node in a given time period; and (2) to evaluate the effect of the undesirable outputs/inputs on efficiency with assumption that they leave the system at the end of the current time period and re-enter the system at the beginning of the next time period. To prove the effectiveness of this DEA model, eighteen scenarios with different demands, capacities, and multiple periods are compared. In addition, this study tests the DEA model on a wafer testing/probing operation of a leading global semiconductor manufacturing and testing company in Taiwan by internal supply chain perspective. Results show that the DEA model proposed in this study can be used to assess the efficiency of a real-world operation with undesirable outputs/inputs, such as inventory and delayed demands.     

Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice

Exposure to ambient ozone (O3) is associated with increased exacerbations of asthma. We sought to determine whether mast cell degranulation is induced by in vivo exposure to O3 in mice and whether mast cells play an essential role in the development of pulmonary pathophysiological alterations induced by O3. For this we exposed mast cell-deficient WBB6F1-kitW/kitW-v (kitW/kitW-v) mice and the congenic normal WBB6F1 (+/+) mice to air or to 1 or 3 parts/million O3 for 4 h and studied them at different intervals from 4 to 72 h later. We found evidence of O3-induced cutaneous, as well as bronchial, mast cell degranulation. Polymorphonuclear cell influx into the pulmonary parenchyma was observed after exposure to 1 part/milllion O3 only in mice that possessed mast cells. Airway hyperresponsiveness to intravenous methacholine measured in vivo under pentobarbital anesthesia was observed in both kitW/kitW-v and +/+ mice after exposure to O3. Thus, although mast cells are activated in vivo by O3 and participate in O3-induced polymorphonuclear cell infiltration into the pulmonary parenchyma, they do not participate detectably in the development of O3-induced airway hyperresponsiveness in mice.     

The role of state policies and programs in buffering the effects of poverty on children's immunization receipt

OBJECTIVES: This study assessed the influence of public policies on the immunization status of 2-year old children in the United States. METHODS: Up-to-dateness for the primary immunization series was assessed in a national sample of 8100 children from the 1988 National Maternal and Infant Health Survey and its 1991 Longitudinal Follow-Up. RESULTS: Documented immunization rates of this sample were 33% for poor children and 44% for others. More widespread Medicated coverage was associated with greater likelihood of up-to-dateness among poor children. Up-to-dateness was more likely for poor children with public rather than private sources of routine pediatric care, but all children living in states where most immunizations were delivered in the public sector were less likely to be up to date. Poor children in state with partial vaccine replacement programs were less likely to be up to date than those in free-market purchase states. CONCLUSIONS: While state policies can enhance immunization delivery for poor children, heavy reliance on public sector immunization does not ensure timely receipt of vaccines. Public- and private-sector collaboration is necessary to protect children from vaccine-preventable diseases.