无线化工业控制系统: 架构、关键技术及应用

大型生产设施的安全与能效监控, 迫切需要低功耗、高精度的泛在感知, 高实时、高可靠的无线传输以及动态灵活的生产管控. 为此, 本文首先提出一种扁平架构的无线化工业控制系统. 然后, 围绕感知、传输和控制等核心功能需求, 系统阐述了高实时高可靠的工业无线网络设计及其时−空−频三元联合调控方法, 感知终端的变周期精益采样和高能效精准时间同步方法, 以及管控平台的语义化互操作和赋时工作流模型等核心关键技术. 最后, 研发了面向石油高效采收和电网全域安全监测的无线化工业控制系统, 介绍了应用效果和成效.     

泡沫铜相变材料在运血车中的储能应用研究

为解决运血车制冷机组反复启停和耗能大的问题,提出了采用泡沫铜相变储能管顺排布置于风道的方案.针对储能管进行了相变储能实验,获得了相变材料温度-时间的变化曲线.针对储能管和运血车风道系统建立了相应的数学模型和物理模型,采用数值模拟方法研究了储能管相变过程和风道加装储能管后的流场和温度场分布.最后对实验结果和仿真结果进行了对比.结果表明,加装泡沫铜相变储能装置可以改善运血车制冷机组的性能.研究结果对泡沫铜相变材料的应用和运血车制冷系统改进具有重要的工程意义.     

Silencing DTX3L Inhibits the Progression of Cervical Carcinoma by Regulating PI3K/AKT/mTOR Signaling Pathway

Cervical carcinoma (CC) is the second most prevalent gynecologic cancer in females across the world. To obtain a better understanding of the mechanisms underlying the development of CC, high-resolution label-free mass spectrometry was performed on CC and adjacent normal tissues from eight patients. A total of 2631 proteins were identified, and 46 significant differently expressed proteins (DEPs) were found between CC and normal tissues (p < 0.01, fold change >10 or <0.1). Ingenuity pathway analysis revealed that the majority of the proteins were involved in the regulation of eIF4 and p70S6K signaling and mTOR signaling. Among 46 DEPs, Integrinβ6 (ITGB6), PPP1CB, TMPO, PTGES3 (P23) and DTX3L were significantly upregulated, while Desmin (DES) was significantly downregulated in CC tissues compared with the adjacent normal tissues. In in vivo and in vitro experiments, DTX3L knockdown suppressed CC cell proliferation, migration, invasion and xenograft tumorigenesis, and enhanced cell apoptosis. Combination of silencing DTX3L and cisplatin treatment induced higher apoptosis percentage compared to cisplatin treatment alone. Moreover, DTX3L silencing inhibited the PI3K/AKT/mTOR signal pathway. Thus, our results suggested DTX3L could regulate CC progression through the PI3K/AKT/mTOR signal pathway and is potentially a novel biomarker and therapeutic target for CC.     

Compound C Inhibits Renca Renal Epithelial Carcinoma Growth in Syngeneic Mouse Models by Blocking Cell Cycle Progression,Adhesion and Invasion

Compound C (CompC), an inhibitor of AMP-activated protein kinase, reduces the viability of various renal carcinoma cells. The molecular mechanism underlying anti-proliferative effect was investigated by flow cytometry and western blot analysis in Renca cells. Its effect on the growth of Renca xenografts was also examined in a syngeneic BALB/c mouse model. Subsequent results demonstrated that CompC reduced platelet-derived growth factor receptor signaling pathways and increased ERK1/2 activation as well as reactive oxygen species (ROS) production. CompC also increased the level of active Wee1 tyrosine kinase (P-Ser⁶⁴²-Wee1) and the inactive form of Cdk1 (P-Tyr¹⁵-Cdk1) while reducing the level of active histone H3 (P-Ser¹⁰-H3). ROS-dependent ERK1/2 activation and sequential alterations in Wee1, Cdk1, and histone H3 might be responsible for the CompC-induced G2/M cell cycle arrest and cell viability reduction. In addition, CompC reduced the adhesion, migration, and invasion of Renca cells in the in vitro cell systems, and growth of Renca xenografts in the BALB/c mouse model. Taken together, the inhibition of in vivo tumor growth by CompC may be attributed to the blockage of cell cycle progression, adhesion, migration, and invasion of tumor cells. These findings suggest the therapeutic potential of CompC against tumor development and progression.     

脆性各向异性岩石破坏过程数值模拟

在改进刚体弹簧方法的基础上,采用Hoek-Brown准则判断界面破坏,提出各向异性Voronoi网格的生成方法,并引入界面细观参数各向异性的赋值函数,最终建立了脆性各向异性岩石损伤破坏过程的数值模拟方法。利用该方法对文献中的试验结果进行了模拟。计算表明,该方法不仅能成功模拟岩石抗压强度随软弱面倾角变化的“U”形规律,定量上与试验结果吻合良好,而且能同时定量模拟岩石变形特性即弹性模量和泊松比的各向异性特征。     

废弃锂电池电极材料中有价金属的赋存状态

这是一篇冶金工程领域的论文。以废旧磷酸铁锂电池正极粉为对象,开展了以Na₂S₂O₈作为氧化剂,并添加低浓度乙酸作为浸出剂选择性浸锂的研究,考查了Na₂S₂O₈加入量、乙酸浓度、浸出温度、浸出液固比和浸出时间等对锂选择性浸出影响。在乙酸浓度0.3 mol/L、Na₂S₂O₈加入量为理论量的1.1倍,浸出液固比10 mL/g、室温浸出2 h条件下,锂、铁、磷的浸出率分别为98.05%、4.49%和2.46%。     

静态软件缺陷预测方法研究

开源软件缺陷预测通过挖掘软件历史仓库的数据,利用与软件缺陷相关的度量元或源代码本身的语法语义特征,借助机器学习或深度学习方法提前发现软件缺陷,从而减少软件修复成本并提高产品质量. 漏洞预测则通过挖掘软件实例存储库来提取和标记代码模块,预测新的代码实例是否含有漏洞,减少漏洞发现和修复的成本. 通过对2000年至2022年12月软件缺陷预测研究领域的相关文献调研,以机器学习和深度学习为切入点,梳理了基于软件度量和基于语法语义的预测模型. 基于这2类模型,分析了软件缺陷预测和漏洞预测之间的区别和联系,并针对数据集来源与处理、代码向量的表征方法、预训练模型的提高、深度学习模型的探索、细粒度预测技术、软件缺陷预测和漏洞预测模型迁移六大前沿热点问题进行了详尽分析,最后指出了软件缺陷预测未来的发展方向.

     

圆筒网涂层激光清除的扫描覆盖模型研究

为了提高圆网聚合物覆膜激光清除中扫描覆盖率及光强分布均匀性,提出了一种线式扫描轨迹光强叠覆优化模型。通过分析圆筒转速与激光单点光斑轨迹,分析了清洗区域光斑在圆筒表面的覆盖域规律,建立激光线式扫描轨迹运动函数;由此建构了激光扫描覆盖模型,探究了圆筒转速、激光扫描线速度以及激光平移速度的关联关系,分析了联合运动的激光光斑分布规律;最后,通过与光斑高斯光强进行拟合分析,得到了圆筒转速与光强均度优化参数,实现激光在圆筒网的能量均匀覆盖。对镍金属圆网表面聚合物涂层进行激光辐照实验,并利用红外光谱测试仪检测样本,实验表明:圆网清洗区域涂层特征峰吸光度近似一致,验证了优化参数下光强分布的均匀性。     

6种典型流场中超声流量计校准系数随企业污染源烟气排放量变化研究

采用计算流体力学方法,对6种典型流场中超声流量计校准系数随企业污染源烟气不同流速变化的规律进行研究。分析不同负荷下超声流量计校准系数相对标准偏差在不同声道角度、管道直径、声道布置形式、上游直管段长度、管道形式时的变化规律。通过国家烟道流量计量标准装置进行实验验证,验证结果表明:不同负荷下校准系数相对标准偏差均未超过1%,且可以通过单负荷校准实现对烟道超声流量计的校准。     

用时域有限差分法研究圆柱形谐振器

本文建立了圆柱坐标系下的时域有限差分(FD-TD)算法程序。运用算法分析了几种圆柱形谐振器(包括同轴形,圆柱形介质加载和开放式柱形介质谐振器)在各种模式下的谐振频率。数值结果与理论值、实验值进行了比较,表明具有很高的精度。本文还对计算中网格的选取原则进行了探讨;并计算了一种双层介质加载腔的谐振频率,从中得出一些有益的结论。