Lena E. Josch  Volker Götz  Christian Römer  Natalia Konchakova  Stefan Emrich  Christine Wagner  Ralf Müller  Michael Kopnarski  Alois K. Schlarb 《Advanced Engineering Materials》2013,15(9):830-836

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Michael Christian Gwinner  Elisabeth Koroknay  Liwei Fu  Piotr Patoka  Witold Kandulski  Michael Giersig  Harald Giessen 《Small (Weinheim an der Bergstrasse, Germany)》2009,5(3)

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  总被引：1，自引：0，他引：1  

Christian Mittelstedt 《International Journal of Engineering Science》2008,46(10):1011-1034

Longitudinal stiffeners attached to composite plates may significantly increase the overall buckling loads of the resultant stiffened structure. As long as the bending stiffness EI of the stiffener remains beneath some a priori unknown threshold value EI_min (with E being Young’s modulus and I being the bending moment of inertia), the buckling pattern will usually be of a more or less global nature, meaning that both the plate and the stiffener will exhibit some certain buckling modes. Once a threshold value EI_min for the bending stiffness, also called minimum stiffness, is exceeded, the stiffener more or less remains in its original position in the state of the onset of buckling while the buckling pattern of the stiffened plate is dominated by local buckling modes of the plate itself. The knowledge of this minimum bending stiffness EI_min of longitudinal stiffeners of composite plates is of high practical importance and a predominant design criterion and will be considered in this paper. For the basic load cases uniform compression and pure shear and their combination, simple closed-form analytical approaches will be presented which enable a straightforward and quick yet accurate estimation of the buckling loads (compression) and (shear) of stiffened composite plates on the one hand, and the minimum bending stiffness EI_min of the attached stiffeners on the other hand.  相似文献   

    

Oliver Miesbauer  Marion Schmidt  Horst‐Christian Langowski Prof. Dr. 《真空研究与实践》2008,20(6):32-40

Mass transport through layer systems consisting of polymers and thin inorganic layers Flexible layer systems from polymeric substrates, thin inorganic layers deposited by vacuum coating and additional polymeric layers are frequently in use to obtain high barrier properties, predominantly against oxygen and water vapour. Especially in cases where additional polymeric coatings are able to fill defects in the inorganic layers, barrier properties of the resulting layer systems show a stronger dependence on their thickness. For the transport of condensable substances, especially of water vapour, an additional porosity in the sub‐nm‐size can be assigned to the inorganic layers. This, however, has a negligible effect on gas permeation. Multilayer structures made from substrates and alternating polymeric and inorganic layers show much better barrier properties than single polymeric substrates coated with single inorganic layers. These improvements, however, are less than previously reported here. Moreover, also in these cases, the condensation of water vapour in sub‐nm pores gives much higher rates for the permeation of substances than expected from simple defect models.  相似文献   

    

Michael T. Northen  Christian Greiner  Eduard Arzt  Kimberly L. Turner 《Advanced materials (Deerfield Beach, Fla.)》2008,20(20):3905-3909

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Papp I  Sieben C  Ludwig K  Roskamp M  Böttcher C  Schlecht S  Herrmann A  Haag R 《Small (Weinheim an der Bergstrasse, Germany)》2010,6(24):2900-2906

An efficient synthesis of sialic-acid-terminated glycerol dendron to chemically functionalize 2 nm and 14 nm gold nanoparticles (AuNPs) is described. These nanoparticles are highly stable and show high activity towards the inhibition of influenza virus infection. As the binding of the viral fusion protein hemagglutinin to the host cell surface is mediated by sialic acid receptors, a multivalent interaction with sialic-acid-functionalized AuNPs is expected to competitively inhibit viral infection. Electron microscopy techniques and biochemical analysis show a high binding affinity of the 14 nm AuNPs to hemagglutinin on the virus surface and, less efficiently, to isolated hemagglutinin. The functionalized AuNPs are nontoxic to the cells under the conditions studied. This approach allows a new type of molecular-imaging activity-correlation and is of particular relevance for further application in alternative antiviral therapy.  相似文献   

    

Antoine Legay  Andreas Zilian  Christian Janssen 《International journal for numerical methods in engineering》2011,86(6):667-687

This contribution discusses extended physical interface models for fluid–structure interaction problems and investigates their phenomenological effects on the behavior of coupled systems by numerical simulation. Besides the various types of friction at the fluid–structure interface the most interesting phenomena are related to effects due to additional interface stiffness and damping. The paper introduces extended models at the fluid–structure interface on the basis of rheological devices (Hooke, Newton, Kelvin, Maxwell, Zener). The interface is decomposed into a Lagrangian layer for the solid‐like part and an Eulerian layer for the fluid‐like part. The mechanical model for fluid–structure interaction is based on the equations of rigid body dynamics for the structural part and the incompressible Navier–Stokes equations for viscous flow. The resulting weighted residual form uses the interface velocity and interface tractions in both layers in addition to the field variables for fluid and structure. The weak formulation of the whole coupled system is discretized using space–time finite elements with a discontinuous Galerkin method for time‐integration leading to a monolithic algebraic system. The deforming fluid domain is taken into account by deformable space–time finite elements and a pseudo‐structure approach for mesh motion. The sensitivity of coupled systems to modification of the interface model and its parameters is investigated by numerical simulation of flow induced vibrations of a spring supported fluid‐immersed cylinder. It is shown that the presented rheological interface model allows to influence flow‐induced vibrations. Copyright © 2010 John Wiley & Sons, Ltd.  相似文献   

    

Christian Kallesøe  Cheng‐Yen Wen  Kristian Mølhave  Peter Bøggild  Frances M. Ross 《Small (Weinheim an der Bergstrasse, Germany)》2010,6(18):2058-2064

A technique to study nanowire growth processes on locally heated microcantilevers in situ in a transmission electron microscope has been developed. The in situ observations allow the characterization of the nucleation process of silicon wires, as well as the measurement of growth rates of individual nanowires and the ability to observe the formation of nanowire bridges between separate cantilevers to form a complete nanowire device. How well the nanowires can be nucleated controllably on typical cantilever sidewalls is examined, and the measurements of nanowire growth rates are used to calibrate the cantilever‐heater parameters used in finite‐element models of cantilever heating profiles, useful for optimization of the design of devices requiring local growth.  相似文献   

    

Klinke C  Hannon JB  Afzali A  Avouris P 《Nano letters》2006,6(5):906-910

We have fabricated field-effect transistors from carbon nanotubes using a novel selective placement scheme. We use carbon nanotubes that are covalently bound to molecules containing a hydroxamic acid functionality. The functionalized nanotubes bind strongly to basic metal oxide surfaces, but not to silicon dioxide. Upon annealing, the functionalization is removed, restoring the electronic properties of the nanotubes. The devices thus fabricated show excellent electrical characteristics.  相似文献   

    

Christina Brandenberger  Christian Mühlfeld  Zulqurnain Ali  Anke‐Gabriele Lenz  Otmar Schmid  Wolfgang J. Parak  Peter Gehr  Barbara Rothen‐Rutishauser 《Small (Weinheim an der Bergstrasse, Germany)》2010,6(15):1669-1678

This study addresses the cellular uptake and intracellular trafficking of 15‐nm gold nanoparticles (NPs), either plain (i.e., stabilized with citrate) or coated with polyethylene glycol (PEG), exposed to human alveolar epithelial cells (A549) at the air–liquid interface for 1, 4, and 24 h. Quantitative analysis by stereology on transmission electron microscopy images reveals a significant, nonrandom intracellular distribution for both NP types. No particles are observed in the nucleus, mitochondria, endoplasmic reticulum, or golgi. The cytosol is not a preferred cellular compartment for both NP types, although significantly more PEG‐coated than citrate‐stabilized NPs are present there. The preferred particle localizations are vesicles of different sizes (<150, 150–1000, >1000 nm). This is observed for both NP types and indicates a predominant uptake by endocytosis. Subsequent inhibition of caveolin‐ and clathrin‐mediated endocytosis by methyl‐β‐cyclodextrin (MβCD) results in a significant reduction of intracellular NPs. The inhibition, however, is more pronounced for PEG‐coated than citrate‐stabilized NPs. The latter are mostly found in larger vesicles; therefore, they are potentially taken up by macropinocytosis, which is not inhibited by MβCD. With prolonged exposure times, both NPs are preferentially localized in larger‐sized intracellular vesicles such as lysosomes, thus indicating intracellular particle trafficking. This quantitative evaluation reveals that NP surface coatings modulate endocytotic uptake pathways and cellular NP trafficking. Other nonendocytotic entry mechanisms are found to be involved as well, as indicated by localization of a minority of PEG‐coated NPs in the cytosol.  相似文献