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Journal of Intelligent Manufacturing - In discrete manufacturing, the knowledge about causal relationships makes it possible to avoid unforeseen production downtimes by identifying their root...  相似文献   
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Introduction: End‐stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined. Methods: The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in‐center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health‐related quality of life, self‐reported physical function, mental health and cognition. Serum prolactin concentrations were measured at baseline and 12‐month follow‐up in 70% of the FHN Trial cohort to examine the associations among serum prolactin concentrations and physical, mental and cognitive function and the effects of hemodialysis frequency on serum prolactin. Findings: Among 177 Daily Trial and 60 Nocturnal Trial participants with baseline serum prolactin measurements, the median serum prolactin concentration was 65 ng/mL (25th–75th percentile 48–195 ng/mL) and 81% had serum prolactin concentrations >30 ng/mL. While serum prolactin was associated with sex (higher in women), we observed no association between baseline serum prolactin and age, dialysis vintage, and baseline measures of physical, mental and cognitive function. Furthermore, there was no significant effect of hemodialysis frequency on serum prolactin in either of the two trials. Discussion: Serum prolactin concentrations were elevated in the large majority of patients with ESRD, but were not associated with several measures of health status. Circulating prolactin levels also do not appear to decrease in response to more frequent hemodialysis over a one‐year period.  相似文献   
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This work studies a scheduling problem where each job must be either accepted and scheduled to complete within its specified due window, or rejected altogether. Each job has a certain processing time and contributes a certain profit if accepted or penalty cost if rejected. There is a set of renewable resources, and no resource limit can be exceeded at any time. Each job requires a certain amount of each resource when processed, and the objective is to maximize total profit. A mixed-integer programming formulation and three approximation algorithms are presented: a priority rule heuristic, an algorithm based on the metaheuristic for randomized priority search and an evolutionary algorithm. Computational experiments comparing these four solution methods were performed on a set of generated benchmark problems covering a wide range of problem characteristics. The evolutionary algorithm outperformed the other methods in most cases, often significantly, and never significantly underperformed any method.  相似文献   
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In the information age, the storage and accessibility of data is of vital importance. There are several possibilities to fulfill this task. Magnetic storage of data is a well‐established method and the range of materials used is continuously extended. In this study, the magnetic remanence of thermally sprayed tungsten carbide–cobalt (WCCo)‐coatings in dependence of their thickness is examined. Two magnetic fields differing in value and geometry are imprinted into the coatings and the resulting remanence field is measured. It is found that there are two effects, which in combination determine the effective value of the magnetic remanence usable for magnetic data storage.
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Nitrogen-doped graphene oxide monoliths (GOMs) were readily constructed by crosslinking graphene oxide (GO) using triethylenetetramine (TETA) and hydroxyethyl cellulose (HEC). The addition of HEC was beneficial to the formation of a network structure compared to that in the absence of HEC. The generated monoliths have shown various morphologies with different d spacing, layer thickness, and micropore size. Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) analyses provided evidences for the formation of covalent C–N bonds and some nitrogen-containing heterocyclic composition inside the graphene oxide sheet, indicating that the interaction of GO with the amine crosslinker involved the crosslinking reaction between GO epoxides and amine groups. HEC was also involved in the N-doping reaction via the partial reduction of oxygen in HEC molecules. Analysis of X-ray diffraction (XRD) results indicated that the lattice distance between GO sheets increased after TETA/HEC crosslinking. Thermogravimetric analysis (TGA) confirmed the successful incorporation of crosslinker moieties on the surface of GO sheets. The fabricated GOMs could be used to efficiently adsorb metal ions and arsenate by the introduced polar functional groups on GO sheets and porous structures based on hydrogen bonds, whose morphologies and compositions were confirmed via XRD, scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS).  相似文献   
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We have tested three methods for estimating 2003-2008 elevation changes of Svalbard glaciers from multi-temporal ICESat laser altimetry: (a) linear interpolation of crossover points between ascending and descending tracks, (b) projection of near repeat-tracks onto common locations using Digital Elevation Models (DEMs), and (c) least-squares fitting of rigid planes to segments of repeat-track data assuming a constant elevation change rate. The two repeat-track methods yield similar results and compare well to the more accurate, but sparsely sampled, crossover points. Most glacier regions in Svalbard have experienced low-elevation thinning combined with high-elevation balance or thickening during 2003-2008. The geodetic mass balance (excluding calving front retreat or advance) of Svalbard's 34,600 km2 glaciers is estimated to be −4.3 ± 1.4 Gt y1, corresponding to an area-averaged water equivalent (w.e.) balance of −0.12 ± 0.04 m w.e. y1. The largest ice losses have occurred in the west and south, while northeastern Spitsbergen and the Austfonna ice cap have gained mass. Winter and summer elevation changes derived from the same methods indicate that the spatial gradient in mass balance is mainly due to a larger summer season thinning in the west and the south than in the northeast. Our findings are consistent with in-situ mass balance measurements from the same period, confirming that repeat-track satellite altimetry can be a valuable tool for monitoring short term elevation changes of Arctic glaciers.  相似文献   
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