Database to dynamically aid probe design for virus identification.

Viral infection poses a major problem for public health, horticulture, and animal husbandry, possibly causing severe health crises and economic losses. Viral infections can be identified by the specific detection of viral sequences in many ways. The microarray approach not only tolerates sequence variations of newly evolved virus strains, but can also simultaneously diagnose many viral sequences. Many chips have so far been designed for clinical use. Most are designed for special purposes, such as typing enterovirus infection, and compare fewer than 30 different viral sequences. None considers primer design, increasing the likelihood of cross hybridization to similar sequences from other viruses. To prevent this possibility, this work establishes a platform and database that provides users with specific probes of all known viral genome sequences to facilitate the design of diagnostic chips. This work develops a system for designing probes online. A user can select any number of different viruses and set the experimental conditions such as melting temperature and length of probe. The system then returns the optimal sequences from the database. We have also developed a heuristic algorithm to calculate the probe correctness and show the correctness of the algorithm. (The system that supports probe design for identifying viruses has been published on our web page http://bioinfo.csie.ncu.edu.tw/.)     

Electrically tunable room-temperature 2/spl pi/ liquid crystal terahertz phase shifter

Tunable phase shift up to 360/spl deg/ at 1 THz is demonstrated using electrically controlled birefringence in a vertically aligned nematic liquid crystal (E7) cell, 1.83 mm in thickness. The driving voltage and corresponding field required for a phase shift of 360/spl deg/ at 1 THz are 100 V and 90.5 V/cm, respectively.     

Characteristics of a 12-domain MVA-LCD

A multi-domain (12-domain) vertical alignment liquid crystal display (MVA-LCD) device is proposed and its electro-optic characteristics evaluated through a 3-D simulator. The MVA-LCD exhibits advantages in wide viewing angle, high transmittance, fast response time, and small color shift when a pair of wide view crossed circular polarizers is employed. Potential applications of this MVA-LCD for high quality LCD TVs and computer monitors are emphasized.     

Robust three, dimensional surface contouring method with digital holography

Nowadays digital holography (DH) is applied to thethree di mensional surface contouring,duetoits non-con-tact advantage[1-5].Moreover ,when a lensless Fouriertransform arrangement with the short-coherence lightsourceis employed in a DHrecording system,not…     

Mobile telemedicine sensor networks with low-energy data query and network lifetime considerations

In this paper, we use an integrated architecture that takes advantage of the low cost mobile sensor networks and 3G cellular networks to accommodate multimedia medical calls with differentiated Quality-of-Service (QoS) requirements. We propose a low-energy, distributed, and concentric-zone-based data query mechanism that takes advantages of hierarchical ad hoc routing algorithms to enable a medical specialist to collect physiological data from mobile and/or remote patients. The medical specialist uses cellular network to report patients' data to the medical center. Moreover, we propose a transmission scheme among different zones with balance-based energy efficiency, which can extend network lifetime. We evaluate the validity of our proposals through simulations and analyze their performance. Our results clearly indicate the energy efficiency of the proposed sensor network query algorithms and the efficiency of our multiclass medical call admission control scheme in terms of meeting the multimedia telemedicine QoS requirements.     

Development of a low cost microwave mixer using a broad-band substrate integrated waveguide (SIW) coupler

A low cost single-balanced mixer is designed using a newly designed 90/spl deg/ substrate integrated waveguide (SIW) 3-dB coupler, which takes the advantages of low cost, low profile, and high performance. An X-band single-balanced SIW mixer is designed and fabricated with a standard printed circuit board process. Measured conversion loss of 6.8dB and the wide-band response from 8.5 to 12GHz are presented.     

基于医院信息化系统的再造与实践分析

本文通过对医院信息化系统的作用、应用中存在的问题、再造与实践的分析和研究,为全面提升医院信息系统功能提供参考。在信息化系统再造中,充分利用现代信息技术和科研方法对信息化系统进行改善和更新,对原本的信息化系统功能和流程进行优化,遵循信息化系统再造的"一个中心"和"四大系统"的相关原则,创新信息化系统管理模式,从而为医院提供优质、高效的管理和服务系统。     

用有限元方法分析Si/GaAs的键合热应力

在考虑材料热膨胀系数随温度变化后,采用有限元方法结合ANSYS软件对Si/GaAs键合热应力进行了分析,研究了普通应力、轴向应力和剪切力的分布云图和沿界面的分布.同时提出了新的键合结构以减小热应力的影响,计算结果证明了该结构的有效性.     

DS-SS/EBPSK调制的码分多址研究

为了实现直序扩频扩展的二元相移键控(DS-SS/EBPSK)调制的多址通信,研究了一种DS-SS/EBPSK调制的码分多址实现方法.首先对DS-SS/EBPSK调制信号进行分析,公式化表述了DS-SS/EBPSK的调制过程,得到了可用于解扩和码分多址的等效扩频序列;在此基础上,设计了相关接收机对DS-SS/EBPSK调制信号进行检测,利用不同用户扩频序列互相关很小的特点实现多址传输;最后以m序列为例,仿真了期望用户的误码性能与用户数量和m序列周期长度的关系.仿真结果验证了此种码分多址实现方式的可行性,同时也表明多用户的于扰程度取决于扩频序列之间的互相关性.     

一种1V电压工作的高精度CMOS带隙基准源

基于标准1μmCMOS工艺,针对1V供电电压,设计了一种自偏置PTAT电流产生电路和低电源、高增益的运算放大器,最终实现了低电源工作的带隙基准电路.在1V电源电压下,采用1μm CMOS工艺进行仿真,温度系数在-20～120℃范围内达到13×10-6,低频电源抑制比达到-90dB.