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991.
    
The bioaccessibility of the major carotenoids present in two commercial microalgal supplements in powder form was investigated through a standardized in vitro digestion method. The dried biomass of Arthrospira platensis contained β-carotene (36.8 mg/100 g) and zeaxanthin (20.8 mg/100 g) as the main carotenoids as well as a high content of saturated fatty acids (61% of total fatty acids), whereas that of Chlorella pyrenoidosa was rich in lutein (37.8 mg/100 g) and had a high level of unsaturated fatty acids (65% of total fatty acids). In the case of the latter, lutein bioaccessibility was not statistically enhanced after the replacement of porcine bile extract with bovine bile extract in the in vitro digestion protocol and after the addition of coconut oil (17.8% as against to 19.2% and 19.2% vs. 18.5%, respectively). In contrast, the use of bovine bile extract along with co-digestion with coconut oil significantly enhanced the bioaccessibility of zeaxanthin from A. platensis, reaching the highest bioaccessibility of 42.8%.  相似文献   
992.
    
Experiments conducted in vitro and in vivo, as well as clinical trials for hypoglycemic therapeutics, support the hypoglycemic properties of the lectin γ-conglutin, a Lupinus seed storage protein, by a mechanism not yet been clarified. Structural studies established that binding of γ-conglutin, in native and denatured form, to insulin occurs by a strong binding that resists rupture when 0.4 M NaCl and 0.4 M galactose are present, suggesting that strong electrostatic interactions are involved. Studies on binding of γ-conglutin in native and denatured form to HepG2 membrane glycosylated receptors were conducted, which reveal that only the native form of γ-conglutin with lectin activity is capable of binding to these receptors. Glycosylated insulin receptors were detected on purified HepG2 cell membranes and characterized by 1D and 2D analyses. Preclinical assays with male mice (CD-1) indicated that native and denatured γ-conglutins display antihyperglycemic effect, decreasing glucose in blood comparable after 120 min to that exhibited by the animal group treated with metformin, used to treat T2D and used as a positive control. Measurement of organ injury/functional biomarkers (hepatic, pancreatic, renal, and lipid profile) was comparable to that of metformin treatment or even better in terms of safety endpoints (pancreatic and hepatic biomarkers).  相似文献   
993.
This paper presents the design of a soft IP for JPEG compression targeted for high performance in a FPGA device. The JPEG compressor architecture achieves high throughput with a deep and optimized pipeline and with a multiplierless datapath architecture. The JPEG compressor architecture was designed in a hierarchical and modular fashion and the details of the global architecture and of its modules are presented in this paper. A modular and strictly structural VHDL design is followed to develop the JPEG compressor soft IP. The VHDL codes were synthesized to Altera and Xilinx FPGAs. Synthesis results and relevant performance comparisons with related works are presented. Our high throughput compressor is able to compress 39.8 millions of pixels per second when mapped onto an Altera FLEX 10KE FPGA. Our JPEG soft IP mapped to FLEX 10KE low cost FPGA is able to compress 115 images per second in SDTV resolution (720 × 480 pixels). Considering this SDTV resolution our design is worthy as a core of an M-JPEG video compressor, reaching a real time processing rate of 30 fps, once mapped to the FLEX 10KE FPGA device.  相似文献   
994.
Versioning is an important aspect of web service development, which has not been adequately addressed so far. In this article, we propose extensions to WSDL and UDDI to support versioning of web service interfaces at development-time and run-time. We address service-level and operation-level versioning, service endpoint mapping, and version sequencing. We also propose annotation extensions for developing versioned web services in Java. We have tested the proposed solution for versioning in two real-world environments and identified considerable improvements in service development and maintenance efficiency, improved service reuse, and simplified governance.  相似文献   
995.
To improve the tarnished reputation of WLAN security, the new IEEE 802.11i standard provides means for mutual user authentication and assures confidentiality of user data. However, the IEEE 802.11 link-layer is still highly vulnerable to a plethora of simple, yet effective attacks which further jeopardize the already fragile security of wireless communications.Some of these vulnerabilities are related to limited hardware capabilities of access points and their abuse may result in serious degradation of control over the wireless connection, which, especially in the case of broadcast communication, allows for client hijacking attacks. Although these issues are known and their impact is expected to be less prevalent on modern equipment, this work demonstrates the opposite. In our experimental analysis, we tested frequently used access points, and by forcing them to operate on their performance limits, we identified significant operational anomalies and demonstrated their impact on security by implementing a novel version of the Man-In-The-Middle attack, to which we refer as the Muzzle attack.Secondly, this work describes DiscoSec, a solution for “patching” WLANs against a variety of such link-layer attacks. DiscoSec provides DoS-resilient key exchange, an efficient frame authentication, and a performance-oriented implementation. By means of extensive real-world measurements DiscoSec is evaluated, showing that even on very resource-limited devices the network throughput is decreased by only 22% compared to the throughput without any authentication, and by 6% on more performance-capable hardware. To demonstrate its effectiveness, DiscoSec is available as an open-source IEEE 802.11 device driver utilizing well-established cryptographic primitives provided by the Linux Crypto API and OpenSSL library.  相似文献   
996.
In this paper, we present a review of the recent approaches proposed in the literature for strip-packing problems. Many of them have been concurrently published, given some similar results for the same set of benchmarks. Due to the quantity of published papers, it is difficult to ascertain the level of current research in this area.  相似文献   
997.
In recent years, network coding has emerged as a new communication paradigm that can significantly improve the efficiency of network protocols by requiring intermediate nodes to mix packets before forwarding them. Recently, several real-world systems have been proposed to leverage network coding in wireless networks. Although the theoretical foundations of network coding are well understood, a real-world system needs to solve a plethora of practical aspects before network coding can meet its promised potential. These practical design choices expose network coding systems to a wide range of attacks.We identify two general frameworks (inter-flow and intra-flow) that encompass several network coding-based systems proposed in wireless networks. Our systematic analysis of the components of these frameworks reveals vulnerabilities to a wide range of attacks, which may severely degrade system performance. Then, we identify security goals and design challenges in achieving security for network coding systems. Adequate understanding of both the threats and challenges is essential to effectively design secure practical network coding systems. Our paper should be viewed as a cautionary note pointing out the frailty of current network coding-based wireless systems and a general guideline in the effort of achieving security for network coding systems.  相似文献   
998.
We present a probabilistic model of user affect designed to allow an intelligent agent to recognise multiple user emotions during the interaction with an educational computer game. Our model is based on a probabilistic framework that deals with the high level of uncertainty involved in recognizing a variety of user emotions by combining in a Dynamic Bayesian Network information on both the causes and effects of emotional reactions. The part of the framework that reasons from causes to emotions (diagnostic model) implements a theoretical model of affect, the OCC model, which accounts for how emotions are caused by one’s appraisal of the current context in terms of one’s goals and preferences. The advantage of using the OCC model is that it provides an affective agent with explicit information not only on which emotions a user feels but also why, thus increasing the agent’s capability to effectively respond to the users’ emotions. The challenge is that building the model requires having mechanisms to assess user goals and how the environment fits them, a form of plan recognition. In this paper, we illustrate how we built the predictive part of the affective model by combining general theories with empirical studies to adapt the theories to our target application domain. We then present results on the model’s accuracy, showing that the model achieves good accuracy on several of the target emotions. We also discuss the model’s limitations, to open the ground for the next stage of the work, i.e., complementing the model with diagnostic information.
Heather MaclarenEmail:
  相似文献   
999.
A comprehensive quality model for service-oriented systems   总被引:2,自引:0,他引:2  
In a service-oriented system, a quality (or Quality of Service) model is used (i) by service requesters to specify the expected quality levels of service delivery; (ii) by service providers to advertise quality levels that their services achieve; and (iii) by service composers when selecting among alternative services those that are to participate in a service composition. Expressive quality models are needed to let requesters specify quality expectations, providers advertise service qualities, and composers finely compare alternative services. Having observed many similarities between various quality models proposed in the literature, we review these and integrate them into a single quality model, called QVDP. We highlight the need for integration of priority and dependency information within any quality model for services and propose precise submodels for doing so. Our intention is for the proposed model to serve as a reference point for further developments in quality models for service-oriented systems. To this aim, we extend the part of the UML metamodel specialized for Quality of Service with QVDP concepts unavailable in UML.
Stéphane FaulknerEmail:

Ivan J. Jureta   has, after graduating, summa cum laude, received the Master in Management and Master of International Management, respectively, at the Université de Louvain, Belgium, and the London School of Economics, both in 2005. He is currently completing his Ph.D. thesis at the University of Namur, Belgium, under Prof. Stéphane Faulkner’s supervision. His thesis focuses on quality management of adaptable and open service-oriented systems enabling the Semantic Web. Caroline Herssens   received a Master Degree in Computer Science in 2005 at the Université de Louvain. In 2006, she graduated a Master in Business and Administration from the University of Louvain, with a supply chain management orientation. She is currently a teaching and research assistant and has started a Ph.D. thesis at the information systems research unit at Université de Louvain. Her research interests comprise service-oriented computing, conceptual modeling and information systems engineering. Stéphane Faulkner   is an Associate Professor in Technologies and Information Systems at the University of Namur (FUNDP) and an Invited Professor at the Louvain School of Management of the Université de Louvain (UCL). His current research interests revolve around requirements engineering and the development of modeling notations, systematic methods and tool support for the development of multi-agent systems, database and information systems.   相似文献   
1000.
The southeastern United States (SE-US) has undergone one of the highest rates of landscape changes in the country due to changing demographics and land use practices over the last few decades. Increasing evidence indicates that these changes have impacted mesoscale weather patterns, biodiversity and water resources. Since the Southeast has one of the highest rates of land productivity in the nation, it is important to monitor the effects of such changes regularly. Here, we propose a remote sensing based methodology to estimate regional impacts of urban land development on ecosystem structure and function. As an indicator of ecosystem functioning, we chose net primary productivity (NPP), which is now routinely estimated from the MODerate resolution Imaging Spectroradiometer (MODIS) data. We used the MODIS data, a 1992 Landsat-based land cover map and nighttime data derived from the Defense Meteorological Satellite Program's Operational Linescan System (DMSP/OLS) for the years 1992/1993 and 2000 to estimate the extent of urban development and its impact on NPP. The analysis based on the nighttime data indicated that in 1992/1993, urban areas amounted to 4.5% of the total land surface of the region. In the year 2000, the nighttime data showed an increase in urban development for the southeastern United States of 1.9%. Estimates derived from the MODIS data indicated that land cover changes due to urban development that took place during the 1992-2000 period reduced annual NPP of the southeastern United States by 0.4%. Despite the uncertainties in sensor fusion and the coarse resolution of the data used in this study, results show that the combination of MODIS products such as NPP with nighttime data could provide rapid assessment of urban land cover changes and their impacts on regional ecosystem resources.  相似文献   
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