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131.
Locke Edwin A.; Frederick Elizabeth; Lee Cynthia; Bobko Philip 《Canadian Metallurgical Quarterly》1984,69(2):241
Manipulated self-efficacy and task strategies in the training of 209 undergraduates under high strategy, low strategy, and control conditions. Ss underwent 5 trials and were administered a self-efficacy scale after each trial. Results show that ability, past performance, and self-efficacy were the major predictors of goal choice. Ability, self-efficacy, goals, and task strategies were related to task performance. Self-efficacy was more strongly related to past performance than to future performance but remained a significant predictor of future performance even when past performance was controlled. Self-efficacy ratings for moderate to difficult levels of performance were the best predictors of future performance; a reanalysis of 2 previous goal-setting studies by the first author confirms this finding. (19 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
132.
Claudio O. Gualerzi Attilio Fabbretti Letizia Brandi Pohl Milon Cynthia L. Pon 《Israel journal of chemistry》2010,50(1):80-94
Translation initiation is a complex, multi-step process of fundamental importance in all kingdoms of life, during which the start site of the genetic message transmitted in the form of an RNA molecule (mRNA) is selected, and the level of translation determined. Being the slowest step of protein synthesis, initiation is the phase most often subject to regulation. Here we review, in a historical perspective and focusing mainly on results from our laboratory, the development of our perception of the mechanisms by which the most relevant steps of this pathway occur in bacteria. In particular, we describe: (a) the mechanistics and kinetics of translation initiation; (b) properties of mRNAs with and without Shine–Dalgarno sequence relevant for initiation site selection and translational efficiency; c) ribosomal binding and dissociation of the initiation factors, formation and properties of translation initiation intermediates; (d) the mechanisms by which translation initiation fidelity is ensured. Finally, we provide a short survey of the known translation initiation inhibitors. 相似文献
133.
Anna H. Wolna Aaron M. Fleming Na An Lidong He Henry S. White Cynthia J. Burrows 《Israel journal of chemistry》2013,53(6-7):417-430
Nanopore technology holds high potential for next-generation DNA sequencing. This method operates by drawing an individual single-stranded DNA molecule through a nanoscale pore, while monitoring the current deflections that occur as the DNA passes through. Individual current levels for the four DNA nucleotides have been established by immobilization of an end biotinylated strand in the pore, in which the nucleotide of interest is suspended at the most sensitive region of the ion channel. Due to the inherent reactivity of DNA bases, many modified nucleotides in the genome exist as a result of oxidative and UV insults, among others. Herein, the current levels for common DNA damage lesions 8-oxo-7,8-dihydroguanine, spiroiminodihydantoin, guanidinohydantoin, uridine, abasic sites, thymine dimers, thymine glycol, and 5-iodocytosine were assessed through immobilization experiments. In some cases, the current difference between the damaged and canonical nucleotides was not well resolved; therefore, we took advantage of the chemical reactivity of the new functional groups present to make amine adducts that shifted the current levels outside the range of the native nucleotides. Among the adducts studied, only the 2-aminomethyl-18-crown-6 adduct was able to give a large current shift in the immobilization experiment, as well as being observed in a translocation experiment. The results show potential in providing current-level modulators for identification of some types of DNA damage. In principle, any DNA base modification that can be converted chemically or enzymatically into an abasic site could be identified in this way. 相似文献
134.
Andrea Zocca Cynthia M. Gomes Enrico Bernardo Ralf Müller Jens Günster Paolo Colombo 《Journal of the European Ceramic Society》2013,33(9):1525-1533
Highly porous (>60% open porosity) glass–ceramic scaffolds with remarkable mechanical properties (compression strength of ~15 MPa) were produced by indirect 3D printing. Precursor glass powders were printed into 3D ordered structures and then heat treated to sinter and develop crystalline phases. The final glass–ceramic contained a β-spodumene solid solution together with a secondary phase of lithium disilicate.The precision of the printed geometry and the density of the struts in the scaffold depended on several processing parameters (e.g. powder size and flowability, layer thickness) and were improved by increasing the binder saturation and drying time. Two types of powders with different particle size distribution (PSD) and flowability were used. Powders with a larger PSD, could be processed within a wider range of printing parameters due to their good flowability; however, the printing precision and the struts density were lower compared to the scaffolds printed using the powder in a smaller average PSD. 相似文献
135.
Lena Arnold Gauthier Averlant Dr. Stefan Marx Mathias Weickert Ulrich Müller Jonathan Mertel Carsten Horch Mikulas Peksa Frank Stallmach 《化学,工程师,技术》2013,85(11):1726-1733
With the increasing demand for alternative fuels the storage of natural gas (NG) in adsorbents like metal organic frameworks (MOFs) will become more important. In order to use MOFs as storage media in fuel delivery systems, the optimization of mass and energy transfer of the system is crucial. For rapid NG filling of a tank, molecules need to reach the adsorption sites within a reasonable time while the heat of adsorption should be dissipated to the environment. In this article, mass transfer in shaped bodies of MOFs was determined by permeability measurements and pulsed field gradient (PFG) NMR spectroscopy. The heat dissipation was also experimentally measured and both data sets were used to set up a theoretical density function theory model to predict the behavior of MOFs for NG storage. 相似文献
136.
Two experiments explore whether synchrony between peak circadian arousal periods and time of testing influences inhibitory efficiency for younger and older adults. Experiment 1 assesses inhibitory control over no-longer-relevant thoughts, and Experiment 2 assesses control over unwanted but strong responses, as well as performance on neuropsychological tasks that index frontal function. Inhibitory control is greatest at optimal times for both age groups and is generally greater for younger than for older adults. Performance on 2 neuropsychological measures (Stroop and Trails) also changes over the day, at least for older adults, and is correlated with inhibitory indexes, suggesting that for older adults changes in inhibition may be mediated by circadian variations in frontal functioning. By contrast, access to well-learned responses is not vulnerable to synchrony or age effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
137.
Drew Linda M.; Berg Cynthia; King Pamela; Verdant Claudia; Griffith Katrina; Butler Jorie; Wiebe Deborah J. 《Canadian Metallurgical Quarterly》2011,25(5):751
For adolescents with Type 1 diabetes, lower family income may be associated with poorer diabetes management through depleted parental psychological resources (i.e., higher parental depressive symptoms, lower parental acceptance). Adolescents (N = 252; 46% male) aged 10–14 years with Type 1 diabetes assessed the acceptance of their mother and father (e.g., “gives me the feeling that she likes me as I am”; “she doesn't feel she has to make me over into someone else”). Mothers provided information on family income and demographics. Both mothers and fathers reported their depressive symptoms. HbA1c scores were indexed via medical records. Lower family income was associated with higher (i.e., worse) HbA1c, more mother and father depressive symptoms, and less acceptance from both parents. Mediation analyses revealed that the relationship of lower family income with metabolic control occurred indirectly through lower maternal and paternal acceptance and lower adherence. Lower family income may impair the quality of parent—adolescent relationships that are beneficial for good diabetes management. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
138.
Sorption measurements are executed to study the sorption behavior of propylene in a semicrystalline polymer. Decreasing values for the Flory–Huggins interaction parameter with increasing temperature are obtained. Large deviations are found, especially at higher temperatures, compared to data from the literature. Propylene is polymerized in liquid and gaseous propylenes with Me2Si[Ind]2ZrCl2/MAO/SiO2 as the metallocene catalyst. Lower relative reaction rates are found in the gas phase compared to the experiments in the liquid phase. The activation energies from the experiments in both phases are on the same order of magnitude. However, the literature versus experimental sorption data has a large effect on the determined kinetic parameters. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 81: 1193–1206, 2001 相似文献
139.
Drew Michael R.; Yang Cynthia; Ohyama Tatsuya; Balsam Peter D. 《Canadian Metallurgical Quarterly》2004,30(3):163
Three experiments investigated the effects of varying the conditioned stimulus (CS) duration between training and extinction. Ring doves (Streptopelia risoria) were autoshaped on a fixed CS-unconditioned stimulus (US) interval and extinguished with CS presentations that were longer, shorter, or the same as the training duration. During a subsequent test session, the training CS duration was reintroduced. Results suggest that the cessation of responding during an extinction session is controlled by generalization of excitation between the training and extinction CSs and by the number of nonreinforced CS presentations. Transfer of extinction to the training CS is controlled by the similarity between the extinction and training CSs. Extinction learning is temporally specific. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
140.
We examined how adolescents' and mothers' perceptions of cognitive and interpersonal functions of collaboration surrounding Type 1 diabetes differed and how they related to adolescent age, psychosocial, and diabetes adjustment. Adolescents (M = 14.16 years) and mothers completed questionnaires assessing the functions of collaboration for the adolescent, quality of the mother-adolescent relationship, emotional adjustment, and adherence to the diabetes regimen. Confirmatory factor analysis (CFA) of perceptions of collaboration confirmed three dimensions: collaboration to compensate for cognitive function, interpersonal enjoyment, and frequency of collaboration. Although adolescents' and mothers' views of interpersonal enjoyment and frequency of collaboration converged, their perceptions of compensation were unrelated. Mothers' perceptions of adolescents' compensation were unrelated to perceptions of enjoyment and frequency. Both adolescents and mothers perceived less compensation and less enjoyment of collaboration with increasing adolescent age, but only adolescents reported collaborating less frequently with higher age. Better emotional adjustment and adherence occurred when mothers and adolescents perceived enjoying collaboration (controlling for mothers' acceptance) regardless of age. Enjoying collaboration at an interpersonal level may be an important avenue for successful diabetes management during adolescence. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献