In situ determination of solidosity profiles during activated sludge electrodewatering

Two non-invasive techniques were evaluated for the on-line measurement of sludge solidosity profiles during both pressure and electrodewatering operations. In a first approach, a radioactive tracer adsorbed onto the sludge solids was monitored by a gamma camera. Although this technique appeared very flexible in use, the lack of resolution highly limited its usefulness for (electro)dewatering experiments. Improvement in gamma camera resolution by the development of new detectors might, however, increase the future applicability of this technique. In a second technique, nuclear magnetic resonance measurements on a specially designed electrodewatering unit were made. Hereby, reliable on-line measurements of the solidosity profiles of activated sludge during electrodewatering could be made, with a resolution of less than 1mm. Thus, the mechanisms of electroosmotic- and pressure-driven cake dewatering could be illustrated. Given the measurement time required for measuring one sludge profile, both techniques appeared mainly suited for slowly varying processes, such as activated sludge expression, and not for fast changing processes, such as the initial phases of sludge filtration.     

Optimization of sewage sludge conditioning and pressure dewatering by statistical modelling

By using a quadratic model, an assessment was made of the relative importance of different sludge and polyelectrolyte variables with respect to sludge pressure dewatering. It was seen that the polyelectrolyte characteristics and dose dominated the cake dry matter content and that sludge properties were less important, especially the electrophoretic mobility of the sludge, which showed a restricted natural variability over the 10-month sampling period. The developed quadratic model in this study appeared very well suited to quantitatively predict the pressure dewatering properties of sludge, allowing the selection of the dose and polyelectrolyte type that yield the best dewatering result. It was further shown that relatively small deviations from the optimal polyelectrolyte dose caused only small changes in cake dry matter values. The model appeared to be applicable on a long-term basis, as it was able to predict the dewaterability of several sludge samples from the studied wastewater treatment plant after more than 3 years. Finally, the model also allowed an (simplified) economic evaluation, indicating that for high cake disposal costs, the polyelectrolyte should be taken that guarantees the best dewatering results, even if it has to be applied in high doses.     

Determination of charge density and adsorption behaviour of DMAEA-Q-based cationic polymers by fluorimetric analysis

In wastewater and sludge treatment, cationic polymers are applied at large scale. A correct determination of the charge density and adsorption efficiency is of high importance for an economic and ecologically sound operation. Although several analytical techniques exist for charge density and polymer concentration determination, they often suffer from laborious sample pretreatment, complex instrumentation or interference from background components present in sludge. In this work, an alternative method has been studied to determine the charge density of an important series of cationic polymers used in water and sludge treatment, viz. copolymers containing quaternised dimethylaminoethylacrylate (DMAEA-Q). The method is based on the basic hydrolysis of the cationic moiety, resulting in choline chloride, which is measured by a fluorimetric technique based on the enzymatic conversion of choline. It was demonstrated that the new technique ensures a highly reliable determination of the charge density of these polymers, based on a comparison with the traditional charge titration technique and the data supplied by the manufacturer. Moreover, the specificity of the enzymatic conversion method also allows the determination of non-adsorbed polymer in conditioned sludge samples, without interference from other components. As a consequence, it enables the determination of the optimal polymer dose in practical conditioning and dewatering operations.     

Use of Furandicarboxylic Acid and Its Decyl Ester as Additives in the Fischer’s Glycosylation of Decanol by d-Glucose: Physicochemical Properties of the Surfactant Compositions Obtained

2,5-Furandicarboxylic acid is a promising bio-based platform chemical that may serve as a ‘green’ substitute for terephthalate in polyesters. In the present work, straightforward glycosylation of decanol with unprotected and non-activated d-glucose was performed under reduced quantities of sulfuric acid as catalyst (down to 0.9 mol%) in the presence of 2,5-furandicarboxylic acid or its n-decyl ester as additive. Yield of decyl monoglucosides was highly improved by the use of the additives. Moreover, the presence of additive also limited the colouration of the reaction. The physical and chemical properties of the surfactant composition produced were studied and compared to reference compositions. The ultimate biodegradability of furan-2,5-dicarboxylic acid (FDCA) and its n-decyl ester formed or produced in the bulk reaction medium was also studied in order to assess its potential use in surfactant industry.     

Luminescent Assay for the Screening of SARS-CoV-2 MPro Inhibitors

Since the outbreak of SARS-CoV-2 in December 2019 millions of infections have been reported globally. The viral chymotrypsin-like main protease (M^Pro) exhibits a crucial role in viral replication and represents a relevant target for antiviral drug development. In order to screen potential M^Pro inhibitors we developed a luminescent assay using a peptide based probe containing a cleavage site specific for M^Pro. This assay was validated showing IC₅₀ values similar to those reported in the literature for known M^Pro inhibitors and can be used to screen new inhibitors.     

Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask

Background

Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. Our objectives were to assess the cardiovascular effects of reducing air pollution exposure by wearing a facemask.

Methods

In an open-label cross-over randomised controlled trial, 15 healthy volunteers (median age 28 years) walked on a predefined city centre route in Beijing in the presence and absence of a highly efficient facemask. Personal exposure to ambient air pollution and exercise was assessed continuously using portable real-time monitors and global positional system tracking respectively. Cardiovascular effects were assessed by continuous 12-lead electrocardiographic and ambulatory blood pressure monitoring.

Results

Ambient exposure (PM_2.5 86 ± 61 vs 140 ± 113 μg/m³; particle number 2.4 ± 0.4 vs 2.3 ± 0.4 × 10⁴ particles/cm³), temperature (29 ± 1 vs 28 ± 3°C) and relative humidity (63 ± 10 vs 64 ± 19%) were similar (P > 0.05 for all) on both study days. During the 2-hour city walk, systolic blood pressure was lower (114 ± 10 vs 121 ± 11 mmHg, P < 0.01) when subjects wore a facemask, although heart rate was similar (91 ± 11 vs 88 ± 11/min; P > 0.05). Over the 24-hour period heart rate variability increased (SDNN 65.6 ± 11.5 vs 61.2 ± 11.4 ms, P < 0.05; LF-power 919 ± 352 vs 816 ± 340 ms², P < 0.05) when subjects wore the facemask.

Conclusion

Wearing a facemask appears to abrogate the adverse effects of air pollution on blood pressure and heart rate variability. This simple intervention has the potential to protect susceptible individuals and prevent cardiovascular events in cities with high concentrations of ambient air pollution.     

Comparison of different current collecting modes of anode supported micro-tubular SOFC through mathematical modeling

A two-dimensional model comprising fuel channel, anode, cathode and electrolyte layers for anode-supported micro-tubular solid oxide fuel cell (SOFC), in which momentum, mass and charge transport are considered, has been developed. By using the model, tubular cells operating under three different modes of current collection, including inlet current collector (IC), outlet current collector (OC) and both inlet and outlet collector (BC), are proposed and simulated. The transport phenomena inside the cell, including gas flow behavior, species concentration, overpotential, current density and current path, are analyzed and discussed. The results depict that the model can well simulate the diagonal current path in the anode. The current collecting efficiency as a function of tube length is obtained. Among the three proposed modes, the BC mode is the most effective mode for a micro-tubular SOFC, and the IC mode generates the largest current density variation at z-direction.