新型紫外线固化环氧树脂/丙烯酸酯改性水性聚氨酯的合成与性能

合成了一种新型的具有高交联密度和优异涂膜性能的环氧树脂和丙烯酸酯同时改性的紫外线（UV）固化水性聚氨酯（UV-EP-AC-WPUD）。通过环氧基团与以异氰酸酯基团（-N=C=O）封端的聚氨酯预聚体之间的反应引入质量分数为4%的环氧树脂E-20。同时,通过聚氨酯链的-N=C=O与二元丙烯酸酯（PEDA）以及季戊四醇三丙烯酸酯（PETA）的羟基之间的反应引入碳碳双键（C=C）,C=C的含量达到4.65 meq·g-1。 质量分数为3%的光引发剂Irgacure 2959被用于引发涂膜中C=C的聚合,涂膜的凝胶含量在12 s UV辐射之后达到91%,意味着C=C的聚合和交联速度快,同时所得到的涂膜的交联度非常高,不溶于溶剂丙酮,测试表明环氧树脂和两种丙烯酸酯单体已经成功嵌入聚氨酯链中,涂膜具有优异的力学性能和化学性能。     

有机化学实验教学中培养学生独立科研创新能力

有机化学实验是与有机化学理论课程相辅相成的操作技能课程。有机化学实验教学中,在实验原理和实验设计等知识的讲解过程中渗透创新能力培养,并将实验内容与日常生活用品的制作相结合,采用条件自选的实验设计方式,培养学生的自我思考的实验设计理念。将有机化学实验和仪器分析结合起来提高学生的综合能力,结合学生SRTP科研立项、毕业论文等科研实践活动,培养学生的独立科研思路,营造良好的科研氛围,培养学生的科研及创新能力。     

浅谈探索石油化工火灾扑救的新途径、新方法

当前在石油化工生产、加工、输送、储运中常常伴随着易燃、易爆、高温、高压、深冷、有毒有害和腐蚀等危险因素,因此,石油化工行业是一个火灾爆炸危险性大,而且一旦发生火灾爆炸事故,则损失大、伤亡大、影响大的行业,一直是消防保卫的重点。本文简要分析论述了石油化工灾害事故的特点以及一些经验,并在此基础上粗浅分析了石油化工火灾扑救需要完善之处,指挥员面对石油化工火灾,能够达到指挥得当、车辆器材物尽其用,将石油化工火灾事故影响及损失降到最低。     

浅谈OEM与药企发展之路

研究了OEM的发展和现状,结合国内制药企业生存现状,权衡了OEM生产方利弊,进而探讨工业化大生产中的国内制药企业面对复杂的国内外市场环境以及产能过剩的现实条件,能否将OEM作为企业生存发展的途径。     

纯磷脂单分子膜压缩过程中磷脂分子的构象和取向(英文)

On the basis of energy conservation law and surface pressure isotherm, the conformation energy changes of dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) in pure phospholipid monolayer at the air/water interface during compression are derived. The optimized conformations of phospholipids at absolute freedom state are simulated by Gaussian 98 software. Based on following assumptions: (1)the conformation energy change is mainly caused by the rotation of one special bond; (2)the atoms of glycerol near the water surface are active; (3)the rotation is motivated by hydrogen-bond action; (4)the rotation of bond is inertial, one simplified track of conformational change is suggested and the conformations of DPPC and DPPG at different states are determined by the plots of conformation energy change vs. dihedral angle. The thickness of the simulated phospholipid monolayer is consistent with published experimental result. According to molecular areas at different states, the molecular orientations in the compressing process are also developed.     

NTO炸药研究进展

综述了3-硝基-1,2,4-三唑-5-酮(NTO)炸药的合成、结晶、含能盐和压装、浇铸、熔铸三大系列混合炸药及相关性能、应用研究进展。NTO爆速为8 200 m/s,感度大于88 cm,性能良好,利用它的高能与低感可研制出应用于IM的混合炸药,是RDX最有前景的替代物。     

陶二煤矿无烟煤与天然焦在测井曲线反映特征

由于陶二煤矿扩大区受煤系地层隐伏的巨厚层岩浆岩体影响,煤层变质为无烟煤,局部变质为天然焦,通过对本区测井物性参数曲线视电阻率、散射伽玛、自然伽玛物性特征的分析、对比,找出了两者之间明显区分物性特征,并把3个参数曲线结合起来,可以直接有效的利用测井参数曲线解释、划分无烟煤与天然焦。     

Effects of a titanate coupling agent on the mechanical and thermo‐physical properties of talc‐reinforced polyethylene compounds

An experimental study was carried out to investigate the effects of a titanate coupling agent on the mechanical properties, moisture absorption, and thermal conductivity of talc‐filled high‐density polyethylene (HDPE). Talc (0–35 wt %) was used as reinforcement particulate filler in an HDPE matrix and samples were prepared in a micro‐compounder and an injection molding machine. Isopropyl tri(dioctyl)phosphate titanate (0.5 wt %) was used as coupling agent. Composites with and without coupling agent were evaluated for changes in mechanical and thermo‐physical properties, morphology, and void content. Addition of the titanate coupling agent most often resulted in an increase in stiffness and tensile strength. Furthermore, both the void content and the elongation at break of composites were reduced. Results also showed that the coupling agent had no effects on the thermal conductivity, thermal diffusivity, and specific heat capacity of the composites. In addition, it was observed that the coupling agent was more effective at low concentrations of filler. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 40449.     

微通道内液-液两相流研究进展

从流型、传质和应用3个方面,介绍了近年来微通道内液-液两相流的研究进展。液-液两相流型研究内容主要有两部分,即流型的观察、流型谱图的绘制以及考察多种因素对流型的影响,但是具有普适性的流型谱图和流型转变线仍未提出。液-液两相传质研究方法包括实验研究和数值模拟两种,主要研究在液滴流、弹状流和平行流3种稳定流型下的传质过程;且相对于定性研究,定量的传质研究较少。对于微通道内液-液两相流应用研究,主要体现在萃取、材料合成、生物结晶等方面。此外,对今后微通道内液-液两相的流型、传质和应用研究进行了展望,指出需从实验与模拟计算相结合以及拓展微通道内液-液两相流的应用研究两个方面进行深入研究,推进其工业化进程。     

Decreased Fibroblast and Increased Osteoblast Functions on Ionic Plasma Deposited Nanostructured Ti Coatings

Bioactive coatings are in high demand to control cellular functions for numerous medical devices. The objective of this in vitro study was to characterize for the first time fibroblast (fibrous scar tissue forming cells) adhesion and proliferation on an important polymeric biomaterial (silicone) coated with titanium using a novel ionic plasma deposition (IPD) process. Fibroblasts are one of the first anchorage-dependent cells to arrive at an implant surface during the wound healing process. Persistent excessive functions of fibroblasts have been linked to detrimental fibrous tissue formation which may cause implant failure. The IPD process creates a surface-engineered nanostructure (with features usually below 100 nm) by first using a vacuum to remove all contaminants, then guiding charged metallic ions or plasma to the surface of a medical device at ambient temperature. Results demonstrated that compared to currently used titanium and uncoated silicone, silicone coated with titanium using IPD significantly decreased fibroblast adhesion and proliferation. Results also showed competitively increased osteoblast (bone-forming cells) over fibroblast adhesion on silicone coated with titanium; in contrast, osteoblast adhesion was not competitively increased over fibroblast adhesion on uncoated silicone or titanium controls. In this manner, this study strongly suggests that IPD should be further studied for biomaterial applications in which fibrous tissue encapsulation is undesirable (such as for orthopedic implants, cardiovascular components, etc.).