The effect of wheat bran on the excretion of cadmium in rats

The influence of wheat bran as a source of dietary fibre on the excretion of ingested cadmium from diet was studied. The cadmium contents in the diets, faeces, urine, liver, kidney and spleen were determined, as well as the weight gains, the relative weights of the cited organs, and the levels of alkaline phosphatase in serum. No evidence is provided that an increasing portion of wheat bran in the diets induced an increase in cadmium excretion. Changes in the studied toxicity parameters were not found.     

Phase II trial of first-line high-dose ifosfamide in advanced soft tissue sarcomas of the adult: a study of the Spanish Group for Research on Sarcomas (GEIS)

BACKGROUND: The agent Ifosfamide (IFOS) is active against soft tissue sarcomas (STS), and patients who progress to IFOS at doses < or = 10 g/m2 show remissions when exposed to high-dose ifosfamide (HDI) (i.e., doses > 10 g/m2), which supports a dose-response relationship for this drug. Because of a lack of first-line studies in adult STS patients, we decided to test the activity and toxicity of HDI in a phase II trial. PATIENTS AND METHODS: Forty-eight patients were enrolled in the study. IFOS was administered at a dose of 14 g/m2 by continuous infusion over six days every four weeks. Granulocyte-macrophage colony-stimulating factor (GM-CSF) at 5 micrograms/kg/day for 10 consecutive days was systematically administered after an episode of neutropenic fever or a delay in hematologic recovery. Patients were treated until progression or the occurrence of severe toxicity, and surgical rescue was attempted when possible. RESULTS: Six pathology-established complete remissions and 11 partial remissions were observed in 45 assessable patients with a response rate of 37.7% (95% CI: 25.5%-50%). Grade 3-4 toxicity (% of cycles) was noted by hemoglobin (17%), leukocyte (75%), granulocyte (75%) and platelet (13%) counts in 158 evaluable cycles. GM-CSF was administered to 28 patients, and 25 suffered one or more episodes of neutropenic fever. Renal toxicity was mild and reversible with some degree of tubular and glomerular dysfunction detected in up to 60% of patients. Grade 3 CNS toxicity was observed in 32% of patients but only one required interruption of therapy. Sixty-four per cent of the patients had asthenia grade 2-3 and 20% were excluded from the study due to excessive toxicity. There was one treatment-related death. CONCLUSIONS: HDI is an active drug in first-line therapy against adult STS. Different administration schedules should be evaluated in an attempt to improve its therapeutic index.     

北京市 X 线胸透受检者的体表照射量及其分布

本文报道北京市医疗照射剂量调查中,X 线胸透受检者的体表照射量调查方法与结果。采用两阶段抽样法,对门诊胸透调查了33个医院,1525人次,体检胸透调查了21个医院,870人次。门诊胸透和体检胸透一次检查受检者体表参考点处的平均照射量分别为1.29±0.26R 和0.613±0.148R。同时还得到了这两种胸透检查受检者的体表照射量分布。     

低相干函数频响函数的无偏差估计方法

本文详细分析了现有输入噪声模型和输出噪声模型的抗噪声原理,提出了一种能同时抑制输入噪声和输出噪声的无偏差估计模型,它利用二次互功率谱代替通常估计中的自功率谱。使得由于噪声引起的误差可以通过多次平均完全消除。新估计模型的精度与输入噪声和输出噪声的水平无关,仅与统计次数有关。在输入、输出噪声不相关条件下,即使相干函数很低仍能通过多次平均获得具有足够精度的频响函数值。文章最后给出了不同噪声干扰下的(?)估计值、(?)估计值以及本文模型的(?)估计值,并与没有噪声干扰下的H_o 值进行比较。     

Spectral filtering using fibre bragg grating embedded sagnac loop mirror

An approach to achieve spectral filtering is proposed, using a fibre Bragg grating (FBG) embedded polarisation maintaining fibre Sagnac loop mirror (SLM) through temperature tuning. The opposite temperature sensitivities of the FBG Bragg resonance wavelengths and the interferometric peaks of the fibre SLM, as well as their pronounced difference in bandwidth, provide an opportunity to realise spectral filtering.     

基于ANSYS的球磨机回转体模态分析

以Ф3.8m×13m双滑履球磨机为研究对象,利用有限元分析软件ANSYS对其回转体进行模态分析,得到了磨机回转体的前10阶固有频率和振型,并由此确定了回转体易发生疲劳破坏的部位,最后通过结构改进使其动态性能得到了改善。     

用于旋转机械故障诊断的一种张量增强型前向神经网络模型

在多层前向神经网络模型的研究基础上，提出了基于张量的增强型前向神经网络诊断模型，以实现在已知输入模式不变的情况下，增强原始模式的表达，从而提高了诊断的精度。试验结果表明，本模型对工程应用具有较高的实用价值。     

微机在地表移动与变形中的应用

介绍了如何使用微机对矩形工作面开采时地表任意点移动和变形值的计算.     

快速标定斜井皮带安装中腰线的方法

本文介绍快速标定斜井皮带安装中腰线标定要素的计算方法及工作步骤。