全文获取类型
收费全文 | 2661篇 |
免费 | 104篇 |
国内免费 | 17篇 |
专业分类
电工技术 | 62篇 |
综合类 | 12篇 |
化学工业 | 412篇 |
金属工艺 | 121篇 |
机械仪表 | 80篇 |
建筑科学 | 123篇 |
矿业工程 | 13篇 |
能源动力 | 57篇 |
轻工业 | 194篇 |
水利工程 | 26篇 |
石油天然气 | 29篇 |
无线电 | 249篇 |
一般工业技术 | 353篇 |
冶金工业 | 709篇 |
原子能技术 | 82篇 |
自动化技术 | 260篇 |
出版年
2022年 | 28篇 |
2021年 | 38篇 |
2020年 | 17篇 |
2019年 | 32篇 |
2018年 | 42篇 |
2017年 | 37篇 |
2016年 | 38篇 |
2015年 | 49篇 |
2014年 | 43篇 |
2013年 | 130篇 |
2012年 | 69篇 |
2011年 | 119篇 |
2010年 | 76篇 |
2009年 | 84篇 |
2008年 | 106篇 |
2007年 | 110篇 |
2006年 | 115篇 |
2005年 | 78篇 |
2004年 | 80篇 |
2003年 | 71篇 |
2002年 | 57篇 |
2001年 | 38篇 |
2000年 | 44篇 |
1999年 | 54篇 |
1998年 | 205篇 |
1997年 | 115篇 |
1996年 | 71篇 |
1995年 | 55篇 |
1994年 | 62篇 |
1993年 | 53篇 |
1992年 | 43篇 |
1991年 | 30篇 |
1990年 | 31篇 |
1989年 | 33篇 |
1988年 | 38篇 |
1987年 | 41篇 |
1986年 | 27篇 |
1985年 | 34篇 |
1984年 | 32篇 |
1983年 | 18篇 |
1982年 | 23篇 |
1981年 | 26篇 |
1980年 | 26篇 |
1979年 | 27篇 |
1978年 | 22篇 |
1977年 | 38篇 |
1976年 | 44篇 |
1975年 | 14篇 |
1974年 | 18篇 |
1973年 | 13篇 |
排序方式: 共有2782条查询结果,搜索用时 15 毫秒
31.
CM Lucas ED Franke MI Cachay A Tejada ME Cruz RD Kreutzer DC Barker SH McCann DM Watts 《Canadian Metallurgical Quarterly》1998,59(2):312-317
Asymmetric acetylcholinesterase (AChE) is anchored to the basal lamina (BL) of cholinergic synapses via its collagenic tail, yet the complement of matrix receptors involved in its attachment remains unknown. The development of a novel overlay technique has allowed us to identify two Torpedo BL components that bind asymmetric AChE: a polypeptide of approximately 140 kDa and a doublet of 195-215 kDa. These were found to stain metachromatically with Coomassie blue R-250, were solubilized by acetic acid, and were sensitive to collagenase treatment. Upon sequence analysis, the 140 kDa polypeptide yielded a characteristic collagenous motif. Another AChE-binding BL constituent, identified by overlay, corresponded to a heparan sulfate proteoglycan. Lastly, we established that this proteoglycan, but not the collagenous proteins, interacted with at least one heparin binding domain of the collagenic tail of AChE. Our results indicate that at least two BL receptors are likely to exist for asymmetric AChE in Torpedo electric organ. 相似文献
32.
Synthesis of beams with low sidelobe levels is a difficult problem for the case of small phased arrays with few elements. Mutual coupling between elements means that conventional weighting algorithms are not applicable. A technique is presented that calculates a complex weight vector for a five element linear array, giving a reduced sidelobe beam pattern. Sidelobes are reduced by the addition of retrodirective beams to the quiescent beam pattern. No knowledge of the coupling coefficients or element radiation patterns is required 相似文献
33.
AR Barker FN Schrick MJ Lewis HH Dowlen SP Oliver 《Canadian Metallurgical Quarterly》1998,81(5):1285-1290
In the common goby, Pomatoschistus microps (Pisces, Gobiidae), males build nests under mussel shells where they care for the eggs until hatching. To investigate why male common gobies cannibalize their own eggs (filial cannibalism), we conducted a feeding experiment. Males given little food ate from their eggs more often than males given food in excess. However, males given mussel meat in excess did not eat more of their eggs than males fed with both mussel meat in excess and goby eggs. This may suggest that male common gobies cannibalize their eggs to obtain energy rather than essential nutrients lacking in other diets. Moreover, males ate their whole clutch if it was exceptionally small regardless of food treatment, suggesting that males stop investing in their clutch if its reproductive value is less than the cost of guarding it. Thus, whole clutch cannibalism and partial clutch cannibalism seem to be governed by different factors. Furthermore, poorly built nests were associated with starved males, suggesting that nest concealing is costly. There was an association between how well the nest was built and partial clutch filial cannibalism, suggesting that the appearance of the nest may indicate the condition of the male, and thus the risk of filial cannibalism. Copyright 1998 The Association for the Study of Animal Behaviour. 相似文献
34.
35.
M Argenziano DA Dean N Moazami DJ Goldstein EA Rose HM Spotnitz D Burkhoff MC Oz ML Dickstein 《Canadian Metallurgical Quarterly》1998,115(3):700-708
BACKGROUND: Inhaled nitric oxide has been shown to be a potent and selective pulmonary vasodilator. Reports of increases in left ventricular end-diastolic pressure and episodes of pulmonary edema during the clinical use of inhaled nitric oxide in patients with preexisting left ventricular dysfunction have raised concerns that this agent may have myocardial depressant effects. We therefore undertook a study of the effects of inhaled nitric oxide on myocardial contractility in a porcine model of ventricular failure and pulmonary hypertension. METHODS: After inducing heart failure in 10 pigs by rapid ventricular pacing, hemodynamic measurements and pressure-volume diagrams (by the conductance method) were obtained in six animals at baseline and during administration of inhaled nitric oxide at concentrations of 20 and 40 ppm. Myocardial contractile state was assessed by the end-systolic pressure-volume relationship and preload-recruitable stroke work, whereas diastolic function was measured in terms of the end-diastolic pressure-volume relationship and the pressure decay time constant T. RESULTS: Baseline hemodynamics reflected heart failure and pulmonary hypertension, and inhaled nitric oxide induced significant reductions in mean pulmonary artery pressure and pulmonary vascular resistance. Although left ventricular end-diastolic pressure increased during administration of inhaled nitric oxide, no changes were observed in measures of systolic or diastolic function. CONCLUSIONS: Inhaled nitric oxide reduced pulmonary vascular resistance but did not alter myocardial contractility or diastolic function. Increases in left ventricular end-diastolic pressure during inhaled nitric oxide therapy are therefore not due to myocardial depression and may be related to increases in volume delivery to the left side of the heart resulting from reduced pulmonary vascular resistance. 相似文献
36.
Clotilde LM Bernard C Sequera DE Karmali A Fusellier A Carter JM 《Journal of laboratory automation》2012,17(4):309-314
Conventional enzyme-linked immunosorbent assay (ELISA) is a gold standard for screening antibodies and testing for protein or antigen presence. A significant limitation of this assay resides in the fact that only one analyte can be assessed per microplate well. Here, we describe and investigate a new technology consisting of an automated ELISA system in which up to 10 analytes can be measured within one single well, thus improving productivity, accuracy, and repeatability by reducing the amount of human labor required. Another strength of the platform is that a user can load any necessary sets/subsets of beads to perform required assays, with improved flexibility compared to manufactured-loaded arrays for multiplex analysis. We also demonstrate that this system can be used to determine the pathogenicity (i.e., presence of Shiga toxins) and serotype (i.e., Escherichia coli O157) of E. coli isolates. 相似文献
37.
Fatah Chetouane Kash Barker Andrea S. Viacaba Oropeza 《Simulation Modelling Practice and Theory》2012,20(1):99-111
An increasing concern of decision makers when dealing with system design is preparation for a wide range of potentially uncertain operating conditions. This paper provides a novel multiobjective approach for simulation-driven decision making that accounts for not only the conventional average system performance indices, but also (i) upper-tail, or extreme, values of these indices, and (ii) measures of their sensitivity to uncertainty in model parameters. The proposed approach is applied to a hospital emergency department service design case study wherein different design alternatives are compared using total time-in-system performance metric under multiple uncertain operating conditions. 相似文献
38.
Stephen O. Dean 《Journal of Fusion Energy》1988,7(1):25-47
Fusion is an essentially inexhaustible source of energy that has the potential for economically attractive commercial applications with excellent safety and environmental characteristics. The primary focus for the fusion-energy development program is the generation of centralstation electricity. Fusion has the potential, however, for many other applications. The fact that a large fraction of the energy released in a DT fusion reaction is carried by high-energy neutrons suggests potentially unique applications. These include breeding of fissile fuels, production of hydrogen and other chemical products, transmutation or burning of various nuclear or chemical wastes, radiation processing of materials, production of radioisotopes, food preservation, medical diagnosis and medical treatment, and space power and space propulsion. In addition, fusion R&D will lead to new products and new markets.Each fusion application must meet certain standards of economic and safety and environmental attractiveness. For this reason, economics on the one hand, and safety and environment and licensing on the other hand, are the two primary criteria for setting long-range commercial fusion objectives. A major function of systems analysis is to evaluate the potential of fusion against these objectives and to help guide the fusion R&D program toward practical applications. The transfer of fusion technology and skills from the national laboratories and universities to industry is the key to achieving the long-range objective of commercial fusion applications. 相似文献
39.
40.
Kenta H.T. Cho Mhoyra Fraser Bing Xu Justin M. Dean Alistair J. Gunn Laura Bennet 《International journal of molecular sciences》2021,22(12)
Background: Toll-like receptor (TLR) agonists are key immunomodulatory factors that can markedly ameliorate or exacerbate hypoxic–ischemic brain injury. We recently demonstrated that central infusion of the TLR7 agonist Gardiquimod (GDQ) following asphyxia was highly neuroprotective after 3 days but not 7 days of recovery. We hypothesize that this apparent transient neuroprotection is associated with modulation of seizure-genic processes and hemodynamic control. Methods: Fetuses received sham asphyxia or asphyxia induced by umbilical cord occlusion (20.9 ± 0.5 min) and were monitored continuously for 7 days. GDQ 3.34 mg or vehicle were infused intracerebroventricularly from 1 to 4 h after asphyxia. Results: GDQ infusion was associated with sustained moderate hypertension that resolved after 72 h recovery. Electrophysiologically, GDQ infusion was associated with reduced number and burden of postasphyxial seizures in the first 18 h of recovery (p < 0.05). Subsequently, GDQ was associated with induction of slow rhythmic epileptiform discharges (EDs) from 72 to 96 h of recovery (p < 0.05 vs asphyxia + vehicle). The total burden of EDs was associated with reduced numbers of neurons in the caudate nucleus (r2 = 0.61, p < 0.05) and CA1/2 hippocampal region (r2 = 0.66, p < 0.05). Conclusion: These data demonstrate that TLR7 activation by GDQ modulated blood pressure and suppressed seizures in the early phase of postasphyxial recovery, with subsequent prolonged induction of epileptiform activity. Speculatively, this may reflect delayed loss of early protection or contribute to differential neuronal survival in subcortical regions. 相似文献