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71.
Whether a sulfonylurea may be used together with insulin for treating NIDDM has been controversial. One view, based on older studies, has been that the additional benefit is too small or the level of glucose control achieved usually too poor to recommend this method. More recent studies of a more specific way of combining a sulfonylurea with insulin are more supportive. When a single injection of insulin taken in the evening is added to a sulfonylurea at the time of secondary failure of the sulfonylurea alone, glycemic control is quite simply and consistently restored to acceptable levels. At this time in the natural history of NIDDM, evening insulin combined therapy is more effective than a single injection of insulin alone, and just as effective as a more complex multiple-injection regimen without an oral agent. A recent multicenter trial of a new sulfonylurea, glimepiride, in combination with a single injection of 70/30 insulin before dinner has confirmed that this approach is safe and more consistently effective than insulin alone for obese patients beginning insulin in a setting resembling clinical practice. The available evidence suggests this form of combined therapy is suitable for routine use.  相似文献   
72.
Optimal Locations of Groundwater Extractions in Coastal Aquifers   总被引:1,自引:0,他引:1  
A regional water supply management model for coastal aquifers was developed. One of its outcomes is the definition of the optimized locations for groundwater withdrawal. Such a tool permits the analysis of alternative plans for groundwater extraction and the sustainable use of water resources in a coastal aquifer subject to saltwater intrusion. The principal components are the evolutionary optimization and the analytical/numerical simulation models. The optimization technique looks for the best well locations taking into consideration the economic results and the satisfaction of the societal water demand. However these two concerns are conditioned by trying to control the saltwater intrusion, i.e., preserving the environmental equilibrium. The simulation model uses the governing mathematical equations for groundwater movement to find the interface between freshwater and saltwater. Because of the non-linearity in the system and the possibility of a jumping interface, a security distance was defined. This is a controlling variable which can be set by the decision makers. The model was applied to a typical case with interesting results. For example, diagrams showing the relationship between the location of the wells and the security distance(s) are of importance to the managers. It was also crucial to have an understanding of the tradeoffs between groundwater withdrawals, positions of the wells from the coast line, and the security distance. The model was also applied to a real case in order to relate the extractions, distances and artificial recharge (not presented in this paper).  相似文献   
73.
同马大堤施工裂缝情况下的堤坡稳定性分析   总被引:2,自引:0,他引:2  
 在同马大堤一标段防渗墙施工过程中,堤身出现规模不等的裂缝。介绍了堤身存在裂缝情况下,汛期水位骤降时堤防迎水坡抗滑稳定性的计算过程。重点探讨了堤坡稳定分析中工况选择、计算参数选取和强度参数敏感性分析的思路和依据。研究结果为裂缝的工程处理提供了依据。  相似文献   
74.
75.
A boost type converter is described that is suitable for low-voltage DC-supply of fluorescent lamps. It has inherent lamp current limitation (ballast action) and provides the high voltage pulses and electrode heating that are required for igniting the lamp. The proposed circuit is applicable in automotive, emergency, and portable light sources.<>  相似文献   
76.
Is there a relationship between personality and criminal behavior? We addressed this question in a representative birth cohort of 862 male and female 18-yr-olds. Personality was assessed with the Multidimensional Personality Questionnaire (MPQ). The MPQ measures 10 relatively independent personality traits and was not designed to identify offenders. Delinquency was assessed via 3 data sources: self-reports, informant reports, and official records. Variable-centered analyses revealed that MPQ scales indexing negative emotionality and behavioral constraint were consistent predictors of delinquency across the 3 data sources. Person-centered analyses revealed that youths abstaining from delinquency were uniquely characterized by low interpersonal potency. Youths involved in extensive delinquency were uniquely characterized by feelings of alienation, lack of social closeness and risk taking. Advances in understanding criminal behavior can be made through research that places the personality-delinquency link in a developmental context. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
77.
A semianalytical method to estimate the bit-error rate performance of nonsynchronous ASK and FSK optical heterodyne systems is presented. This approach takes into account numerous system details with an accuracy similar to Monte-Carlo simulation, but with a computation time reduced by several orders of magnitude. An analytical approximation, based on a closed-form expression for the decision variable moment generating function, is also presented. The results obtained with the semianalytical method and the analytical approximation are compared to Monte-Carlo simulation results and to measurements obtained on a practical FSK system  相似文献   
78.
土质边坡稳定分析中条分法与有限元法的比较   总被引:7,自引:0,他引:7  
对比分析了土质边坡稳定性计算中条分法和有限元法的特点,讨论了在有限元法中边坡稳定系数的计算方法,并针对铜钟水电站库区左岸滑坡分别采用条分法和有限元法研究其稳定性,计算结果表明两种计算方法得到的滑坡稳定系数规律相同,但条分法计算值一般大于有限元值,反映出条分法中部分基本假设与实际情况存在一定差异。  相似文献   
79.
张弓  朱兆达 《电子学报》2003,31(12):1824-1827
通过设立专门通道将图像处理技术应用于雷达检测域杂波功率数据处理,对特征杂波进行跟踪,为恒虚警处理提供背景信息.本文介绍了对抗杂波边缘的自适应CFAR检测器设计中的研究工作,设计了基于杂波跟踪的杂波属性CF(clutter feature)-CFAR检测器和结构元素SE(structuring element)-CFAR检测器,对其检测性能进行了分析.并通过蒙特卡罗(Monte Carlo)仿真方法对上述两种检测器的检测性能进行了仿真.  相似文献   
80.
Solid polymer electrolytes (SPEs) synthesized by the sol-gel process and designated as di-ureasils have been prepared through the incorporation of lithium perchlorate, LiClO4, into the d-U(2000) organic-inorganic hybrid network. Electrolytes with lithium salt compositions of n (where n indicates the number of oxyethylene units per Li+ ion) between ∞ and 0.5 were characterized by conductivity measurements, cyclic voltammetry at a gold microelectrode, thermal analysis and Fourier transform Raman (FT-Raman) spectroscopy. The conductivity results obtained suggest that this system offers a quite significant improvement over previously characterized analogues doped with lithium triflate [S.C. Nunes, V. de Zea Bermudez, D. Ostrovskii, M.M. Silva, S. Barros, M.J. Smith, R.A. Sá Ferreira, L.D. Carlos, J. Rocha, E. Morales, J. Electrochem. Soc. 152 (2) (2005), A429]. “Free” perchlorate ions, detected in all the samples examined, are identified as the main charge carriers in the sample that yields the highest room temperature conductivity (n = 20). In the di-ureasils with n ≤ 10 ionic association is favoured and the ionic conductivity drops.  相似文献   
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