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81.
In this article, we propose an agent‐based approach for managing e‐commerce activities. In our approach, an agent is present in each e‐commerce site, managing the information stored there. In addition, another agent is associated with each customer, handling his/her profile. The proposed approach is based on the use of a particular conceptual model called the Behaviour‐Semantic Distance and Relevance (B‐SDR) network, which is capable of uniformly representing and handling information stored in e‐commerce sites and customer profiles. The capabilities of the B‐SDR network model are exploited to let customer and site agents cooperate in such a way in order to support a customer in identifying, whenever he/she accesses an e‐commerce site, those products and services present in the site itself and for better matching his/her interests. The approach has been implemented in a prototype in which its functionalities are discussed here also. © 2004 Wiley Periodicals, Inc. 相似文献
82.
83.
Domenico Sanfilippo 《Catalysis Today》1997,34(3-4):261-267
84.
Stefano Sivolella Giulia Brunello Nadia Ferrarese Alessandro Della Puppa Domenico D’Avella Eriberto Bressan Barbara Zavan 《International journal of molecular sciences》2014,15(2):3088-3117
Injury to peripheral nerves can occur as a result of various surgical procedures, including oral and maxillofacial surgery. In the case of nerve transaction, the gold standard treatment is the end-to-end reconnection of the two nerve stumps. When it cannot be performed, the actual strategies consist of the positioning of a nerve graft between the two stumps. Guided nerve regeneration using nano-structured scaffolds is a promising strategy to promote axon regeneration. Biodegradable electrospun conduits composed of aligned nanofibers is a new class of devices used to improve neurite extension and axon outgrowth. Self assembled peptide nanofibrous scaffolds (SAPNSs) demonstrated promising results in animal models for central nervous system injuries, and, more recently, for peripheral nerve injury. Aims of this work are (1) to review electrospun and self-assembled nanofibrous scaffolds use in vitro and in vivo for peripheral nerve regeneration; and (2) its application in peripheral nerve injuries treatment. The review focused on nanofibrous scaffolds with a diameter of less than approximately 250 nm. The conjugation in a nano scale of a natural bioactive factor with a resorbable synthetic or natural material may represent the best compromise providing both biological and mechanical cues for guided nerve regeneration. Injured peripheral nerves, such as trigeminal and facial, may benefit from these treatments. 相似文献
85.
Thermophiles as Potential Source of Novel Endotoxin Antagonists: the Full Structure and Bioactivity of theLipo‐oligosaccharide from Thermomonas hydrothermalis
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Dr. Flaviana Di Lorenzo Dr. Ida Paciello Dr. Luigi Lembo Fazio Dr. Luciana Albuquerque Dr. Luisa Sturiale Prof. Milton S. da Costa Prof. Rosa Lanzetta Prof. Michelangelo Parrilli Prof. Domenico Garozzo Prof. Maria Lina Bernardini Dott. Alba Silipo Prof. Antonio Molinaro 《Chembiochem : a European journal of chemical biology》2014,15(14):2146-2155
Thermomonas hydrothermalis is a Gram‐negative thermophilic bacterium that is able to live at 50 °C. This ability is attributed to chemical modifications, involving those to bacterial cell‐wall components, such as proteins and (glyco)lipids. As the main component of the outer membrane of Gram‐negative bacteria, lipopolysaccharides (LPSs) are exposed to the environment, thus they can undergo structural chemical changes to allow thermophilic bacteria to live at their optimal growth temperature. Furthermore, as one of the major target of the eukaryotic innate immune system, LPS elicits host immune response in a structure‐dependent mode; thus the uncommon chemical features of thermophilic bacterial LPSs might exert a different biological action on the innate immune system—an antagonistic effect, as shown in studies of LPS structure–activity relationship in the ongoing research into antagonist LPS candidates. Here, we report the complete structural and biological activity analysis of the lipo‐oligosaccharide isolated from Thermomonas hydrothermalis, achieved by a multidisciplinary approach (chemical analysis, NMR, MALDI MS and cellular immunology). We demonstrate a tricky and interesting structure combined with a very interesting effect on human innate immunity. 相似文献
86.
Manuela Lasagna Caterina Caviglia Domenico Antonio De Luca 《Bulletin of Engineering Geology and the Environment》2014,73(2):341-355
The Maggiore Valley well field plays a fundamental role in supplying drinking water to a large territory of the Piedmont (north-western Italy). However, an increasing demand for water has led to the overexploitation of the groundwater resources. This situation has caused a progressive drawdown of the piezometric level (locally, up to 0.8 m/year), a spatial reduction in the artesian zone, localised land subsidence and damage to wells. The main purpose of this study was the development of a groundwater flow model of the area for analysing the aquifer response to various pumping strategies. Initially, the groundwater flow simulation (achieved by the application of the MODFLOW code) was calibrated satisfactorily. Then, the groundwater response to four scenarios was simulated to explore the best option to mitigate the problem. In three of the scenarios, a withdrawal reduction of 110 l/s was simulated, whilst considering various relocation options for extraction within the well field. The fourth scenario simulated a withdrawal reduction of 150 l/s; this option also assumed a supplementary water supply from the Monferrato Aqueduct, located north of the study area. All the simulations provided an increase in the piezometric level; in some instances, up to 30 m. Based on these simulations, the most promising management strategy for the Maggiore Valley well field would seem to be the option using a supplementary feed from the Monferrato Aqueduct. In this instance, the predicted piezometric level rise would be up to 25 m; this option also precludes the need for drilling additional wells. 相似文献
87.
Brambilla G De Filippis SP Iamiceli AL Iacovella N Abate V Aronica V Di Marco V di Domenico A 《Journal of food protection》2011,74(2):261-269
An observational study was designed to assess the bioaccumulation of polychlorodibenzodioxins (PCDD) and polychlorodibenzofurans (PCDF), dioxin-like polychlorobiphenyls (DL-PCB), and 13 selected polybromodiphenylethers (PBDE) in autochthonous pigs reared in the Nebrodi Park of Sicily (Italy). Perirenal fat and liver samples were drawn from animals representative of three different outdoor farming systems and from wild pigs and then analyzed for the chemicals mentioned previously. The highest concentrations of PCDD + PCDF and DL-PCB were detected in the fat (0.45 and 0.35 pg World Health Organization toxicity equivalents [WHO-TE] per g of fat base [FB], respectively) and livers (12.7 and 3.28 pg WHO-TE per g FB) of the wild group, whereas the free-ranging group showed the lowest levels (0.05 and 0.03 pg WHO-TE per g FB in fat and 0.78 and 0.27 pg WHO-TE per g FB in livers). The sum of PBDE congeners was highest in wild pigs (0.52 ng/g FB in fat and 5.64 ng/g FB in livers) and lowest in the farmed group (0.14 ng/g FB in fat and 0.28 ng/g FB in livers). The contamination levels in fat and livers of outdoor pigs had mean concentration values lower than those levels reported for intensively indoor-farmed animals. In wild pigs, bioaccumulation was associated with their free grazing in areas characterized by bush fires. The results of this study aid to emphasize the quality of the environment as a factor to guarantee food safety in typical processed pig meat products, specifically from outdoor and extensive Nebrodi farming systems. 相似文献
88.
Vittoria Bruni Daniela De Canditiis Domenico Vitulano 《Signal, Image and Video Processing》2014,8(7):1199-1209
This paper presents SUVEHP (speed up of video enhancement based on human perception), a human perception-based model oriented to reduce the computational time of digital video restoration. In particular, two specific hypothesis tests able to classify degraded frame regions are proposed. Classification is performed in agreement with regions visual significance in order to enable or inhibit motion compensated enhancement. The level of the proposed hypothesis tests is theoretically assessed. Moreover, extensive experimental results on video sequences affected by additive Gaussian noise show that SUVEHP speeds up some standard motion compensated denoisers up to 60%, preserving or even slightly increasing both the objective and subjective visual quality of the restored sequences. 相似文献
89.
Italy produces approximately 4,520,000 tons of pasta annually, which is about 67% of its total productive potential. As factories need electric and thermal energy simultaneously, combined heat and power (CHP) systems are the most suitable. This paper describes a feasibility study of a CHP plant in a pasta factory in Italy while analyzing energy saving and environmental benefits. Commercially available CHP systems suitable for the power range of energy demand in pasta production use reciprocating engines or gas turbines. This study demonstrates how their use can reduce both energy costs and CO2 equivalent greenhouse gas emission in the environment. An economic analysis was performed following the methodology set out by Italian National Agency for Technology, Energy and Environment (ENEA) based on a discounted cash flow (DCF) method called “Valore Attuale Netto” (VAN), which uses a cash flow based on the saving of energy when using different energy processes. 相似文献
90.
Jos L Tambosi Michele Di Domenico Waldir N Schirmer Humberto J Jos Regina de FPM Moreira 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2006,81(8):1426-1432
A Fenton‐like process, involving oxidation and coagulation, was evaluated for the removal of odorous compounds and treatment of a pulp and paper wastewater. The main parameters that govern the complex reactive system [pH and Fe(III) and hydrogen peroxide concentrations] were studied. Concentrations of Fe(III) between 100 and 1000 mg L?1 and of H2O2 between 0 and 2000 mg L?1 were chosen. The main mechanism for color removal was coagulation. The maximum COD, color and aromatic compound removals were 75, 98 and 95%, respectively, under optimal operating conditions ([Fe(III)] = 400 mg L?1; [H2O2] = 500–1000 mg L?1; pH = 2.5; followed by coagulation at pH 5.0). The biodegradability of the wastewater treated increased from 0.4 to 0.7 under optimal conditions and no residual hydrogen peroxide was found after treatment. However, partially or non‐oxidized compounds present in the treated wastewater presented higher acute toxicity to Artemia salina than the untreated wastewater. Based on the optimum conditions, pilot‐scale experiments were conducted and revealed a high efficiency in relation to the mineralization of organic compounds. Terpenes [(1S)‐α‐pinene, β‐pinene, (1R)‐α‐pinene and limonene] were identified in the wastewater and were completely eliminated by the Fenton‐like treatment. Copyright © 2006 Society of Chemical Industry 相似文献