Effect of naftidrofuryl (LS129) on axonal growth

Wistar rats, eight days old, were subjected to permanent bilateral forebrain ischemia, followed by hypoxia for 15 minutes. A cerebral infarct, mainly involving the cerebral neocortex, hippocampus, amygdala, striatum and subcortical white matter was produced. Neurons and glia showing punctate chromatin condensation and karyorrhectic cells were observed 12 hours after hypoxia-ischemia. Their number increased during the first two days and recruitment of cells with degenerating nuclei occurred until day five. In situ labeling of nuclear DNA fragmentation stained many normal-appearing nuclei, as well as punctate chromatin condensations and nuclear fragments in karyorrhectic cells. Delayed neuronal death in the CA1 area of the hippocampus was observed after 20 minutes of transient forebrain ischemia in the adult gerbil. In situ labeling of nuclear DNA fragmentation demonstrated stained punctate chromatin condensation in a few degenerating cells at 48 hours post-ischemia. Substantial labeling of CA1 neurons occurred in the fourth day. Agarose gel electrophoresis of extracted brain DNA from ischemic infant rats and adult gerbils showed a ladder-type pattern which is typical of nuclear DNA fragmentation into oligonucleosomal fragments (internucleosomal cleavage). These findings suggest that endonuclease(s) activation may play a role in cell death induced by different forms of hypoxia-ischemia.     

Quasi-optical multiplexer based on reflecting diffraction grating

The article presents results of theoretical and experimental investigation of quasioptical multiplexer based on reflecting diffraction grating. Diffraction losses caused by reflection into mirror harmonic, and by angle divergence of wave beams are calculated. In an experimental multiplexer, wave beams with the frequencies 70 GHz and 79 GHz were mixed with power losses less than 1%.     

Expert system “assistent” for bayes' intellectual measurements of probability characteristics

Translated from Izmeritel'naya Tekhnika, No. 8, pp. 11–14, August, 1992.     

Gradient interpenetrating polymer networks

The methods of synthesis and properties of gradient interpenetrating polymer networks (IPN) are discussed based on literature and authors' own experimental data. Gradient IPN can be treated as a sequence of an infinite number of layers of IPNs, whose composition and properties vary gradually from the surface to the core of specimens. These are analysed the most important properties of gradient IPNs: temperature transitions, thermodynamic and physico-mechanical characteristics and the main direction of practical application of gradient IPN-based materials.     

Improved Prediction of Ozone Levels in Urban and Rural Atmospheres

Based on data obtained in terms of the first International cooperative program on the effects of acidic precipitations on materials (ICP Materials) of the United Nations European Commission on Economics (UN ECE), the relations between the ozone O₃ and nitrogen dioxide NO₂ concentrations in combination with the sunshine effect (taken into account either as the solar radiation (Rad) or the sunshine duration (Sun)) are considered. Analysis based on monthly and annual averages led to a new equation recommended for predicting ozone levels over rural, urban, and industrial areas of Europe as a function of NO₂ concentration and Sun parameter. Using Rad instead of Sun provides similar results, but, for practical usage, the equation involving a more easily available parameter Sun was recommended. The new equation corrects and improves the earlier proposed one, in which the concentration of ozone was given as a function of NO₂ concentration solely, and is included in the UN ECE Manual on mapping critical loads / levels and geographical areas where they are exceeded.     

Manufacture of a high-quality alkylsalicylate additive at the Novokuibyshevsk Petroleum Refinery

Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 4, pp. 16–17, April, 1992.