Lysosomes and essential fatty acid deficiency

The hydrolytic activity usually associated with lysosomes increased in the homogenates and subcellular fractions of rat liver as a result of essential fatty acid (EFA) deficiency. The proportion of the total (tissue homogenate) activity found in each subcellular fraction, however, was unchanged by EFA deficiency. Lysosomes isolated from normal and EFA-deficient rat livers differed significantly in their stability to thermal and osmotic variations. This suggested that lysosomal membranes, like other membranes, were altered by EFA deficiency. In spite of increased tissue-bound hydrolytic activity and altered lysosomal membranes, hydrolytic activity of the serum was not markedly changed in EFA deficiency. These minor changes in hydrolytic activity and in lysosomal membrane stability seemed insufficient to explain the general lesions of EFA deficiency. Published with the approval of the Director of The Wisconsin Agricultural Experiment Station.     

Reaction of fatty acids with N-methyl taurine

A commercially feasible process has been developed for producing salt-free fatty acyl taurates. The products are especially suited for soap-synthetic bars, contributing most importantly limesoap dispersing properties. Presented at the AOCS meeting in Los Angeles, Calif., 1959.     

Regeneration of the spinal ventral roots. An experimental study in cats

From a clinical standpoint recovery of spinal nerve roots is less likely than that of peripheral nerves, despite their identical structures. This may be due to several factors including the length of gap to be bridged, changes in the proximal stump or neuroma, and chromatolysis. In this paper we discuss the roles of some of these factors in relation to the neuronal depopulation in the spinal cord anterior horn area following section of the anterior root. The lack of growth or the successful growth of the axon through the gap in the root influences the degree of depopulation in the anterior horn area.     

Feeding deterrency of some pyrrolizidine,indolizidine, and quinolizidine alkaloids towards pea aphid (Acyrthosiphon pisum) and evidence for phloem transport of indolizidine alkaloid swainsonine

Journal of Chemical Ecology - The feeding deterrency of a series of pyrrolizidine, indolizidine, and quinolizidine alkaloids and selected derivatives was measured against the pea aphid...