Analysis of the Stability of I-Walls with Gaps between the I-Wall and the Levee Fill

Following Hurricane Katrina an extensive investigation of the performance of floodwalls in the New Orleans area was undertaken by the U. S. Army Corps of Engineers and others. This investigation included detailed study of failures of cantilevered sheet pile “I-walls” during the hurricane. An important lesson from this investigation was that gaps can form on the canal side of I-walls as the water rises in the canal and causes the I-wall to deflect. Once formed, these gaps filled with water, resulting in significantly higher loads on the walls. Gap formation was a key factor in several I-wall failures, and modeling such gaps correctly is clearly an important aspect of analyzing I-wall stability. This paper describes simple procedures for estimating the depths of gaps behind I-walls, for calculating the loads to which they are subjected, and for including them in stability analyses. The effects of gaps on the stability of the 17th Canal and the London Avenue Canal I-walls are discussed.     

Effect of pulse consumption on perceived flatulence and gastrointestinal function in healthy males

Despite their demonstrated health benefits, consumption of pulses in Western societies has traditionally been low. This is, in part, due to the perception that pulses cause flatulence and gastrointestinal upset. This randomized, double-blind placebo-controlled, cross-over study assessed the impact of 28 consecutive days consumption of 100 g dry weight Kabuli chickpeas, green Laird lentils, and green peas, in comparison to a potato control, on perceived flatulence, abdominal comfort, bowel movements and overall gastrointestinal function using a questionnaire with yes/no and visual analog rankings, in 21 healthy males between the ages of 19–40. Questionnaires were completed during three phases (PRE, EARLY, LATE) of each treatment period. Chi-square (occurrence) and Wilcoxon test (severity rank) analyses revealed minor changes in occurrence and/or severity of flatulence and abdominal comfort, but no changes in overall gastrointestinal function. These results demonstrate that pulses containing oligosaccharides are well tolerated with negligible perceived changes in flatulence and overall gastrointestinal function when incorporated into the diet of healthy adult males.     

Biomedical applications of thermally activated shape memory polymers

Shape memory polymers (SMPs) are smart materials that can remember a primary shape and can return to this primary shape from a deformed secondary shape when given an appropriate stimulus. This property allows them to be delivered in a compact form via minimally invasive surgeries in humans, and deployed to achieve complex final shapes. Here we review the various biomedical applications of SMPs and the challenges they face with respect to actuation and biocompatibility. While shape memory behavior has been demonstrated with heat, light and chemical environment, here we focus our discussion on thermally stimulated SMPs.     

Invariants, Patterns and Weights for Ordering Terms

We prove that any simplification order over arbitrary terms is an extension of an order by weight, by considering a related monadic term algebra called the spine. We show that any total ground-stable simplification order on the spine lifts to an order on the full term algebra. Conversely, under certain restrictions, a simplification ordering on the term algebra defines a weight function on the spine, which in turn can be lifted to a weight order on the original ground terms which contains the original order. We investigate the Knuth–Bendix and polynomial orders in this light. We provide a general framework for ordering terms by counting embedded patterns, which gives rise to many new orderings. We examine the recursive path order in this context.     

An Examination of the Relationship Between Transition State Geometry in Hydron Transfer Reactions and the Temperature Dependence of the Primary Kinetic Isotope Effect

Several recent papers by Kwart feature hydron transfer reactions in which the primary kinetic isotope effect is temperature independent over wide temperature ranges. It has been asserted (without theoretical justification) that this phenomenon is associated with transition state X….H….Y bond angles which are significantly less than 180°, whereas normal temperature dependence may be associated with transition states in which the angle is close to 180°. This work employs model calculations of isotope effects, principally for [1,5] H-shifts in 1,3-pentadiene, to examine Kwarts's hypothesis. No model tested yielded a temperature-independent isotope effect of substantial magnitude. The transition state (angle = 133°) was located on the MNDO potential energy surface and the isotope effect, calculated by a new and fast computational procedure, was again temperature dependent. Model calculations of secondary hydrogen isotope effects were carried out. When bending motions of the non-reacting hydrogens were coupled to C….H stretching modes in the force constant matrix, it was found that kH/kD was greater than the equilibrium secondary isotope effect, k_H/K_D, and that k_H/k_D for hydrogen transfer exceeded k_H/k_D for deuteron transfer when simple tunnel corrections were incorporated. A novel interpretation to account for the observation of some temperature-independent isotope effects is advanced.     

Enantioselectivity of recombinant Rhizomucor miehei lipase in the ring opening of oxazolin-5(4H)-ones

Enantioselectivity of enzyme catalysis is often rationalizedvia active site models. These models are constructed on thebasis of comparing the enantiomeric excess of product observedin a series of reactions which are conducted with a range ofhomologous substrates, typically carrying various side chainsubstitutions. Surprisingly the practical application of thesesimple but informative `pocket size' models has been rarelytested in genetic engineering experiments. In this paper wereport the construction, purification and enantioselectivityof two recombinant Rhizomucor miehei lipases which were designedto check the validity of such a model in reactions of ring openingof oxazolin-5(4H)-ones.     

Human Physiological Capabilities for Prolonged Manual Lifting Tasks

The objective of this study was to determine human physiological capabilities for prolonged lifting tasks performed from the floor to table height. Frequency and weight of load were the independent variables. Oxygen consumption, minute ventilation, and heart rate were the dependent variables. Physiological responses were monitored continuously for each frequency-load combination. Eleven male subjects participated in the experiments. The duration of each experimental session was controlled by the subject. Each subject was instructed to perform the lifting task continuously until he could not maintain it any longer due to complete physical exhaustion. Each subject was given 10 minutes of rest every 50 minutes of work and 1 hour for lunch after the fourth hour of work. The upper limit of lifting duration was set to 8 hours. One of the main findings obtained from this study was that a physiological fatigue limit (PFL) is a function of lifting task parameters (frequency, weight of load, and task duration). Thus, one cannot recommend a single PFL value such as 1 liter/min for lifting tasks of varied work durations.