Titania and Noble Metals Deposited Titania Catalysts in the Photodegradation of Tartazine

Nanoparticles of TiO₂ were synthesised by sol–gel technique and photo deposition of about 1% noble metal (M/TiO₂, M = Ag, Au, and Pt) on TiO₂ was carried out. The catalysts were characterised by XRD, TEM, BET, FT-IR, and UV–Visible spectroscopy. Using commercial TiO₂ (P-25 Degussa), the conditions such as dye concentration, catalyst weight and pH were optimized for complete decolourisation of textile dye tartazine (TAZ) under UV and visible irradiations. Among the catalysts tested, the synthesised TiO₂ showed better photocatalytic activity than TiO₂ (P-25 Degussa). Whereas, M/TiO₂ catalysts showed remarkable photocatalytic activity towards the decolourisation of TAZ even under visible irradiation. This enhanced activity of M/TiO₂ catalyst may be attributed to the trapping of conduction band electrons by noble metals.     

Plasma Membrane Receptors Involved in the Binding and Response of Osteoclasts to Noncellular Components of the Bone

Osteoclasts differentiate from hematopoietic cells and resorb the bone in response to various signals, some of which are received directly from noncellular elements of the bone. In vitro, adherence to the bone triggers the reduction of cell–cell fusion events between osteoclasts and the activation of osteoclasts to form unusual dynamic cytoskeletal and membrane structures that are required for degrading the bone. Integrins on the surface of osteoclasts are known to receive regulatory signals from the bone matrix. Regulation of the availability of these signals is accomplished by enzymatic alterations of the bone matrix by protease activity and phosphorylation/dephosphorylation events. Other membrane receptors are present in osteoclasts and may interact with as yet unidentified signals in the bone. Bone mineral has been shown to have regulatory effects on osteoclasts, and osteoclast activity is also directly modulated by mechanical stress. As understanding of how osteoclasts and other bone cells interact with the bone has emerged, increasingly sophisticated efforts have been made to create bone biomimetics that reproduce both the structural properties of the bone and the bone’s ability to regulate osteoclasts and other bone cells. A more complete understanding of the interactions between osteoclasts and the bone may lead to new strategies for the treatment of bone diseases and the production of bone biomimetics to repair defects.     

Lipase-catalyzed synthesis of isoamyl butyrate: Optimization by response surface methodology

Immobilized lipase from Mucor miehei (Lipozyme IM-20) was employed in the esterification of butyric acid and isoamyl alcohol to synthesize isoamyl butyrate in n-hexane. Response surface methodology based on five-level, five-variable central composite rotatable design was used to evaluate the effects of important variables—enzyme/substrate (E/S) ratio (5–25 g/mol), acid concentration (0.2–1.0 M), alcohol concentration (0.25–1.25 M), incubation period (12–60 h), and temperature (30–50°C)—on esterification yield of isoamyl butyrate. In the range of parameters studied, the extent of esterification decreased with temperature, lower E/S ratios, and incubation periods. Excess acid and alcohol concentrations (i.e., acid/alcohol >1.4 or alcohol/acid >1.4) were found to decrease yield probably owing to inhibition of the enzyme by acid or alcohol, the former being more severe. The optimal conditions achieved are as follows: E/S ratio, 17 g/mol; acid concentration, 1.0 M; incubation period, 60 h; alcohol concentration, 1.25 M; and temperature, 30°C. With these conditions, the predicted value was 1.0 M ester, and the actual experimental value was 0.98 M.     

Degumming rice bran oil using phospholipase‐A1

The efficacy of enzymatic degumming was assessed using the third generation phospholipase‐A₁, Lecitase®‐Ultra (EC 3.1.1.3) from Thermomyces lanuginosa/Fusarium oxysporum with different qualities of crude rice bran oil. The phosphorus content in the oil reduced to ～10 mg/kg from an initial level of 390 mg/kg after 2 h of incubation period at 50°C. However, in the solvent‐phase degumming, there was practically no phospholipid reduction at lower water content (2%) due to the poor contact between the highly nonpolar solvent and the aqueous phase (citric acid, NaOH, and enzyme solutions). Increasing the water content to 20% reduced the phosphorus level in the degummed‐oil to 71 mg/kg but did not match the performance of oil‐phase degumming. The degumming efficiency of Lecitase®‐Ultra was effective in oil‐phase and suitable for practical application. Solvent‐phase enzymatic degumming offers more benefits but needs greater efforts to overcome the challenges.     

Amyloglucosidase-catalyzed synthesis of n-octyl-d-glucoside—analysis using response surface methodology

Amyloglucosidase (3.2.1.3)-catalyzed synthesis of n-octyl-d-glucoside was optimized using response surface methodology. A central composite rotatable design involving 32 experiments of five variables at five levels was employed to study the glucosylation reaction. Among the variables studied, namely, n-octanol (15–75 MEq to d-glucose), enzyme (20–100 mg ), pH (4.0–8.0), buffer volume (0.2–1.0 ml) and temperature (30–70°C), amyloglucosidase concentration, pH and temperature were found to be significant. Experimental data fitted the second-order polynomial equation well, as indicated by an R² value of 0.895. Validation experiments carried out under predicted conditions showed good correspondence between experimental and predicted yields. Various surface plots were generated to describe the relationship between operating variables and the conversion yields. The highest yield of 53.5% predicted at optimum conditions of 75 Eq n-octanol, 20 mg amyloglucosidase, 0.2 ml, pH 7.8 buffer at 50 °C showed good correspondence to the experimental yield of 53.8% under these conditions.     

Novel topologies for DC-DC converter with PWM control

Two topologies for the buck converter are presented. The first converter consists of two active switches whereas the second converter, derived from the parent twoswitch converter, consists of only one active switch. The main feature of this new converter is the ability to operate at a constant switching frequency using a simple PWM control. The design of the gate circuit is simplified as there is only one switch. The converter has a good efficiency, as is proved by the experimental results. The operation of the parent two-switch converter, from which the new single-switch converter is derived, is also presented to gain insight into the design of the new converter.     

Fast Evaluation of the Room Transfer Function Using Multipole Expansion

Reverberation in rooms is often simulated with the image method due to Allen and Berkley (1979). This method has an asymptotic complexity that is cubic in terms of the simulated reverberation length. When employed in the frequency domain, it is relatively computationally expensive if there are many receivers in the room or if the source or receiver positions are changing with time. The computational complexity of the image method is due to the repeated summation of the fields generated by a large number of image sources. In this paper, a fast method to perform such summations is presented. The method is based on multipole expansion of the monopole source potential. For offline computation of the room transfer function for N image sources and M receiver points, use of the Allen-Berkley algorithm requires O(NM) operations, whereas use of the proposed method requires only O(N+M) operations, resulting in significantly faster computation of reverberant sound fields. The proposed method also has a considerable speed advantage in situations where the room transfer function must be rapidly updated online in response to source/receiver location changes. Simulation results are presented, and algorithm accuracy, speed, and implementation details are discussed. For problems that require frequency-domain computations, the algorithm is found to generate sound fields identical to the ones obtained with the frequency-domain version of the Allen-Berkley algorithm at a fraction of computational cost     

Superconductivity in dense Mg11-xMxB2 (M = Zr, Nb, Mo; x = 0.05) materials sintered under pressure

Dense compacts of superconducting MgB₂ material have been produced by sintering under 3 GPa pressure and 900°C using a cubic anvil apparatus. The starting material was produced by the powder in tube (PIT) method at low pressure and in argon atmosphere. The effect of substitution of Mg sites with non-magnetic 4d-transition metals (Zr, Nb, Mo) on the superconducting transition temperature (T inc) has been studied by resistivity and susceptibility measurements. The results indicate that there is a small gradual reduction in the transition temperature as we move from Zr to Mo.     

Synthesis and Structural Characterization of V–4Ti–4Cr Alloy

V–(4–10)Ti–(4–5)Cr alloys are the potential candidate materials for the high performance structural applications in fusion power systems due to their favorable mechanical and physical properties. In the present study, the alloy design has been attempted through model based approach for pre mentioned composition range. Thermodynamic calculations have been carried out through Miedema model for this alloy system. The enthalpy difference—composition plot for the ternary V–Ti–Cr system indicate the stability of the solid solution phase in this composition range, which is also in agreement with the atomic size variation which is well within the 15 % size variation limit. Based on these plots, an alloy with a composition of V–4Ti–4Cr is considered as the reference composition for our study. The alloys have been prepared by melting the desired compositions of highly pure metals in a water cooled vacuum arc melting unit. For structural information, X-ray diffraction experiment has been carried out. The XRD pattern does not contain any signature for the secondary phase formation. The structure is bcc structure with small variation in lattice parameter from that of pure vanadium. Transmission electron microscopy characterization has also been carried out, which confirms the absence of fine secondary phases and the crystal structure as b.c.c.