Review of A Triune Concept of the Brain and Behaviour.

Reviews the book, A Triune Concept of the Brain and Behaviour by Paul D. MacLean, edited by T. J. Boag and D. Campbell. This volume contains the three Hincks Memorial Lectures given by Paul D. MacLean at Queen's University, Kingston, Ontario together with a number of supporting papers. The lectures were given in 1969 but not published until four years later. MacLean first presents an evolutionary view of the brain as having developed in three stages with each stage being superimposed upon the previous one. The scope of MacLean's discourse is very wide and, as is common in lectures of this type, rather speculative. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Incorporation of a venturi device in electrospray ionization

Electrospray ionization has grown to be one of the most commonly used ionization techniques for mass spectrometry, and efforts continue to improve its performance. Typically, the sprayer tip must be very close to the entrance orifice of the mass spectrometer in order to maximize the conduction of ions from the sprayer into the mass spectrometer. However, because of space-charge repulsion, most ions never reach the sampling orifice. In this work, an industrial air amplifier, for which the working mechanism is based on venturi and coanda effects, was added between an electrospray ionization source and a time-of-flight mass spectrometer. When a series of reserpine solutions (0.5, 1.0, 5.0, and 10.0 microM) were monitored using mass spectrometry, an over 5-fold increase in m/z 609.3 ion intensity was measured for a separation distance of 14 mm between the electrospray tip and interface capillary inlet, as compared to when the electrospray tip was in its normal position 1 mm in front of the inlet without the amplifier. When a voltage was applied to the air amplifier to further assist in focusing the electrosprayed ions, an approximately 18-fold increase in m/z 609.3 ion intensity was obtained. In addition, a 34-fold reduction in method detection limit was observed.     

V2O5 nanofibre sheet actuators

Vanadium oxides, such as V2O5, are promising for lithium-ion batteries, catalysis, electrochromic devices and sensors. Vanadium oxides were proposed more than a decade ago for another redox-dependent application: the direct conversion of electrical energy to mechanical energy in actuators (artificial muscles). Although related conducting polymer and carbon nanotube actuators have been demonstrated, electromechanical actuators based on vanadium oxides have not be realized. V2O5 nanofibres and nanotubes provide the potential advantages of low-cost synthesis by sol-gel routes and high charging capacity and long cycle life. Here, we demonstrate electromechanical actuation for obtained high modulus V2O5 sheets comprising entangled V2O5 nanofibres. The high surface area of these V2O5 sheets facilitates electrochemical charge injection and intercalation that causes the electromechanical actuation. We show that the V2O5 sheets provide high Young's modulus, high actuator-generated stress, and high actuator stroke at low applied voltage.     

The abstract selection task: New data and an almost comprehensive model.

A complete quantitative account of P. Wason's (1966) abstract selection task is proposed. The account takes the form of a mathematical model. It is assumed that some response patterns are caused by inferential reasoning, whereas other responses reflect cognitive processes that affect each card selection separately and independently of other card selections. The model parameters assess the contributions of different interpretational, inferential, and heuristic factors that jointly determine performance in the selection task. The interpretation of most of the model parameters in terms of these different factors is validated experimentally. This model of the selection task is the first to account for the observed frequencies of all 16 possible response patterns that can arise. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

<Emphasis Type="Italic">Vive les differences?</Emphasis> Developing a profile of European information systems research as a basis for international comparisons

The information systems (IS) community is truly international, yet there is often a sense that different elements of the community have different profiles in terms of their research and publication expectations. This paper contributes to this discussion by developing a profile of European IS research that can be used as a basis for international comparisons. It reflects on European research on IS as presented during the first 10 years of the European Conference on Information Systems (ECIS). Based on an analysis of all papers published in the ECIS proceedings during the period 1993–2002, the paper presents the key characteristics of the ECIS conferences, together with a profile of European IS research activity as presented at ECIS. In particular, it highlights the key references and sources used by researchers presenting papers at ECIS. It articulates the research areas presented at ECIS and explores the claim that European IS draws more on social theories than elsewhere. Its contribution in presenting a profile of European research in the IS field lies in identifying particular characteristics of the European style of research that can be compared to that undertaken in other parts of the world.     

CULTURE: A STRESSED SYSTEM

As for fuzzy closed loop control systems composed of fuzzy relation de scribed process and controller this paper proposes an analytical method for the stability of fuzzy closed loop control systems using fuzzy relations and a design method for constructing a stable fuzzy controller As a result the paper develops the theory of fuzzy control systems Examples are given to illustrate how to use the method for the analysis and design of fuzzycontrol systems     

Confusion,social knowledge and the design of intelligent machines

This paper explores the notion of confusion as it applies to the design of intelligent machines and suggests that it arises from the social nature of knowledge. It provides a framework for analysing the causes of confusion and shows how confusion normally reveals itself after the cause of the confusion has occurred. This places practical limitations on how intelligent machines can react to confusion when it is noticed. The paper also describes a prototype system that aims to minimize the effects of confusion by allowing the users to explore the design rationale of the system.     

An Overview of Synergistic Data Tools for Biological Scrutiny

A network of biological databases is reviewed, supplying a framework for studies of human genes and the association of their genomic variations with human phenotypes. The network is composed of GeneCards, the human gene compendium, which provides comprehensive information on all known and predicted human genes, along with its suite members GeneDecks and GeneLoc. Two databases are shown that address genes and variations focusing on olfactory reception (HORDE) and transduction (GOSdb). In the realm of disease scrutiny, we portray MalaCards, a novel comprehensive database of human diseases and their annotations. Also shown is GeneKid, a tool aimed at generating novel kidney disease biomarkers using systems biology, as well as Xome, a database for whole-exome next-generation DNA sequences for human diseases in the Israeli population. Finally, we show LifeMap Discovery, a database of embryonic development, stem cell research and regenerative medicine, which links to both GeneCards and MalaCards.     

High and very high temperature reactor research for multipurpose energy applications

Ten years ago, the European High Temperature Reactor (HTR) Technology Network (HTR-TN) launched a programme for developing HTR Technology, which expanded so far through 4 successive Euratom Framework Programmes. Many projects have been performed - in particular the RAPHAEL project in the 6th Euratom Framework Programme and presently ARCHER in the 7th - in line with the Network strategy that identified cogeneration of process heat and power as the main specific mission of HTR. HTR can indeed address the growing energy needs of industry presently fully relying on fossil fuel combustion with a CO₂-lean generation technology, thanks to its high operating temperature and to its unique flexibility obtained from its large thermal inertia and its low power.Relying on the legacy of the former European leadership in HTR technology, this programme has addressed specific developments required for industrial process heat applications and for increasing HTR performances (higher temperatures and fuel burn-up). Decisive achievements have been obtained concerning fuel manufacturing and irradiation behaviour, key components and their materials, safety, computer code validation and specific HTR waste (fuel and graphite) management. Key experiments have been performed or are still ongoing: irradiation of graphite, fuel and vessel materials and the corresponding post-irradiation examinations, safety tests and isotopic analyses; thermal-hydraulic tests of an Intermediate Heat Exchanger mock-up in helium; air ingress experiments for a block type core, etc. Through Euratom participation in the Generation IV International Forum (GIF), these achievements contribute to international cooperation.HTR-TN strategy has been recently integrated by the “Sustainable Nuclear Energy Technology Platform” (SNE-TP) as one of the 3 “pillars” of its global nuclear strategy. It is also in line with the orientations and the timing of the “Strategic Energy Technology Plan (SET-Plan)” for the development of CO₂-lean energy technologies, and thus strengthens the nuclear option in a future European energy mix.Nuclear cogeneration for industrial process heat applications is a major innovation and a major challenge, requiring large-scale demonstration to prove its industrial viability. To enable demonstration, it is necessary not only to develop an appropriate nuclear heat source, but also to develop coupling technologies and to adapt industrial processes to the coupling with a HTR. This requires a close partnership between the conventional and the nuclear technology holders as the base of a Nuclear Cogeneration Industrial Initiative.Recently the project EUROPAIRS initiated by HTR-TN together with process heat user industries has set the bases of such a strategic partnership.     

Exploring the bibliometric and semantic nature of negative results

Negative results are not popular to disseminate. However, their publication would help to save resources and foster scientific communication. This study analysed the bibliometric and semantic nature of negative results publications. The Journal of Negative Results in Biomedicine (JNRBM) was used as a role model. Its complete articles from 2002–2009 were extracted from SCOPUS and supplemented by related records. Complementary negative results records were retrieved from Web of Science in “Biochemistry” and “Telecommunications”. Applied bibliometrics comprised of co-author and co-affiliation analysis and a citation impact profile. Bibliometrics showed that authorship is widely spread. A specific community for the publication of negative results in devoted literature is non-existent. Neither co-author nor co-affiliation analysis indicated strong interconnectivities. JNRBM articles are cited by a broad spectrum of journals rather than by specific titles. Devoted negative results journals like JNRBM have a rather low impact measured by the number of received citations. On the other hand, only one-third of the publications remain uncited, corroborating their importance for the scientific community. The semantic analysis relies on negative expressions manually identified in JNRBM article titles and abstracts and extracted to syntactic patterns. By using a Natural Language Processing tool these patterns are then employed to detect their occurrences in the multidisciplinary bibliographical database PASCAL. The translation of manually identified negation patterns to syntactic patterns and their application to multidisciplinary bibliographic databases (PASCAL, Web of Science) proved to be a successful method to retrieve even hidden negative results. There is proof that negative results are not only restricted to the biomedical domain. Interestingly a high percentage of the so far identified negative results papers were funded and therefore needed to be published. Thus policies that explicitly encourage or even mandate the publication of negative results could probably bring about a shift in the current scientific communication behaviour.