Use of the MMPI-2 in American Indians: I. Comparability of the MMPI-2 Between Two Tribes and With the MMPI-2 Normative Group.

The comparability of the MMPI-2 in American Indians with the MMPI-2 normative group was investigated in a sample of 535 Southwestern and 297 Plains American Indian tribal members with contrasting sociocultural and historical origins. Both American Indian tribal groups had clinically significant higher T scores (>5 T points) on 5 validity and clinical scales, 6 content scales, and 2 supplementary scales than did the MMPI-2 normative group. There were no significant differences between the 2 tribal groups on any of the MMPI-2 clinical, content, or supplementary scales. Matching members of both tribes with persons in the MMPI-2 normative group on the basis of age, gender, and education reduced the magnitude of the differences between the 2 groups on all of these scales, although the differences in T scores still exceeded 5 T points. It appears likely that the MMPI-2 differences of these 2 American Indian groups from the normative group may reflect their adverse historical, social, and economic conditions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Feed horn coupled bolometer arrays for SPIRE - design, simulations, and measurements

In this paper, we present the design, modeling, and measurements of feed horn coupled large bolometer arrays being developed for the Herschel Space Observatory's Spectral and Photometric Imaging REceiver (SPIRE) instrument. SPIRE has five arrays of feed horn coupled silicon-nitride micromesh "spider-web" bolometers in two instruments, a three-band photometer, and a two-band Fourier transform spectrometer, each covering the 430-GHz-1.5-THz band. The optical coupling efficiency, bandwidth, and crosstalk between adjacent pixels of the arrays were investigated with numerical electromagnetic-field simulators, and prototype arrays were measured extensively in a test facility. The measured results were found to be in good agreement with simulation predictions, and the simulation results were used as a benchmark for the design goals of the instrument.     

Predictors of hemorrhagic transformation occurring spontaneously and on anticoagulants in patients with acute ischemic stroke

We describe a case of microscopic polyangiitis involving skin and joints after influenza vaccination. Titers of antiinfluenza A antibody were markedly elevated in synovial fluid (SF) relative to those in serum. Antiinfluenza B antibodies were not present in SF but were present in serum, suggesting a reaction specifically involving antiinfluenza A antibodies localized to the affected joint. A review identified 16 other cases of vasculitis after influenza vaccination. The cases reclassified according to the Chapel Hill diagnostic criteria identified multiple forms of vasculitis including 7 other cases of microscopic polyangiitis. Three patients had similar illnesses after previous influenza vaccination or influenza-like illness. As in our case 11 cases resolved without recurrence. While this does not provide conclusive evidence that the vaccination caused the vasculitis, together with the serologic data we present it supports this hypothesis.     

The phosphorylation state of translation initiation factors is regulated developmentally and following heat shock in wheat

Several translation initiation factors in mammals and yeast are regulated by phosphorylation. The phosphorylation state of these factors is subject to alteration during development, environmental stress (heat shock, starvation, or heme deprivation), or viral infection. The phosphorylation state and the effect of changes in phosphorylation of the translation initiation factors of higher plants have not been previously investigated. We have determined the isoelectric states for the wheat translation initiation factors eIF-4A, eIF-4B, eIF-4F, eIF-iso4F, and eIF-2 and the poly(A)-binding protein in the seed, during germination, and following heat shock of wheat seedlings using two-dimensional gel electrophoresis and Western analysis. We found that the developmentally induced changes in isoelectric state observed during germination or the stress-induced changes were consistent with changes in phosphorylation. Treatment of the phosphorylated forms of the factors with phosphatases confirmed that the nature of the modification was due to phosphorylation. The isoelectric states of eIF-4B, eIF-4F (eIF-4E, p26), eIF-iso4F (eIF-iso4E, p28), and eIF-2alpha (p42) were altered during germination, suggesting that phosphorylation of these factors is developmentally regulated and correlates with the resumption of protein synthesis that occurs during germination. The phosphorylation of eIF-2beta (p38) or poly(A)-binding protein did not change either during germination or following a thermal stress. Only the phosphorylation state of two factors, eIF-4A and eIF-4B, changed following a heat shock, suggesting that plants may differ significantly from animals in the way in which their translational machinery is modified in response to a thermal stress.     

Dynamic three-dimensional echocardiographic reconstruction of congenital cardiac septation defects

DNA and FISH (fluorescence in situ hybridization) analysis were carried out in 12 patients with stigmata of Turner syndrome to determine whether the Supernumerary Marker Chromosome (SMC) found cytogenetically in each of these patients was derived from the Y chromosome. The presence of a Y chromosome in these patients may predispose them to develop gonadoblastoma. PCR-Southern blot analysis, followed by FISH, was used to detect the presence of Y chromosome material. The Sex determining Region Y (SRY), Testis Specific Protein Y-encoded (TSPY) and Y-chromosome RNA Recognition Motif (YRRM) genes, which map at Yp11.31, Yp11.1-11.2 and Yp11.2/Yq11.21-11.23, respectively, were selected as markers, because they span the whole Y chromosome, and more importantly, they are considered to be involved in the development of gonadoblastoma. It was shown that in 12 patients, all of whom had an SMC, the SMC of 11 was derived from the Y chromosome. Furthermore, the presence of the SRY, TSPY and YRRM gene sequences was determined and FISH analysis confirmed the Y origin of the SMCs. The methodology described in this report is a rapid, reliable and sensitive approach which may be easily applied to determine the Y origin of an SMC carried in Turner syndrome. The identification of an SMC is important for the clinical management and prognostic counseling of these patients with Turner syndrome.     

Effect of social skills training groups and social skills bibliotherapy with psychiatric patients.

The effectiveness of a systematic social skills group training program was compared to both a bibliotherapy program group and a typical hospital treatment control group (10 18–56 yr old patients per group). Assessment instruments included self-report (Rathus Assertiveness Schedule), observational, and in vivo measures. Results on the observational measure show that the skills training group improved significantly more than the control group, and this difference was maintained at follow-up. The skills group also showed superior improvement on the self-report measure. Results fail to demonstrate the efficacy of bibliotherapy. Findings concerning generalization of social skills group treatment effectiveness were encouraging in that 2 of 3 measures employed to test for generalization showed significant effects. (3 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An improved instrument for the rapid determination of capacitance in electrochemical systems

The design and operation of an instrument for the direct, continuous monitoring of electrode capacitance under potentiostatic conditions is described. Accurate values of the capacitance can be obtained over two orders of magnitude of capacitance, even in the presence of low parallel resistances.     

INTEGRATED PERFORMANCE SUPPORT

Integrated performance support systems provide management with the vehicle to train workers In a new educational paradigm—providing information when and where it is needed. This column looks at how integrated performance support systems apply adult-learning principles to enable the work force to achieve performance requirements and meet business objectives.     

Telepresence feedback and input systems for a twin armed mobilerobot

Complex tasks in unstructured/hazardous environments often require teleoperation. The telepresence robot featured here has “user friendly” limb linked output and feedback systems. The mechanism design and sensory feedback of visual, audio and multi-functional tactile (pressure, texture/slip and thermal parameters) are described