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21.
Elena Molina Mercedes Ramos Pedro J. Martin-álvarez 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1995,201(4):331-335
Stepwise multiple linear regression (SMLR) and principal components regression (PCR) have been used to predict the percentages of cows', goats' and ewes' milk in Iberico cheese, using the results obtained by electrophoretic analysis (PAGE and IEF) of whey proteins, using standard cheeses. Similar predictions of the percentages of milks from the three species were obtained when either SMLR or PCR were applied to the electrophoretic data, i.e. the optical intensity of the electrophoretic bands (PAGE or IEF) of the whey proteins. The root mean square error of prediction in cross-validation (RMSEPCV) was lower than 4% in all cases. 相似文献
22.
Mónica Giménez‐Marqués Elena Bellido Thomas Berthelot Teresa Simón‐Yarza Tania Hidalgo Rosana Simón‐Vázquez África González‐Fernández José Avila Maria Carmen Asensio Ruxandra Gref Patrick Couvreur Christian Serre Patricia Horcajada 《Small (Weinheim an der Bergstrasse, Germany)》2018,14(40)
Controlling the outer surface of nanometric metal–organic frameworks (nanoMOFs) and further understanding the in vivo effect of the coated material are crucial for the convenient biomedical applications of MOFs. However, in most studies, the surface modification protocol is often associated with significant toxicity and/or lack of selectivity. As an alternative, how the highly selective and general grafting GraftFast method leads, through a green and simple process, to the successful attachment of multifunctional biopolymers (polyethylene glycol (PEG) and hyaluronic acid) on the external surface of nanoMOFs is reported. In particular, effectively PEGylated iron trimesate MIL‐100(Fe) nanoparticles (NPs) exhibit suitable grafting stability and superior chemical and colloidal stability in different biofluids, while conserving full porosity and allowing the adsorption of bioactive molecules (cosmetic and antitumor agents). Furthermore, the nature of the MOF–PEG interaction is deeply investigated using high‐resolution soft X‐ray spectroscopy. Finally, a cell penetration study using the radio‐labeled antitumor agent gemcitabine monophosphate (3H‐GMP)‐loaded MIL‐100(Fe)@PEG NPs shows reduced macrophage phagocytosis, confirming a significant in vitro PEG furtiveness. 相似文献
23.
Elena Baralis Stefano Ceri Piero Fraternali Stefano Paraboschi 《Journal of Intelligent Information Systems》1996,7(2):129-149
The lack of tools for rule generation, analysis, and run-time monitoring appears one of the main obstacles to the widespreading of active database applications. This paper describes a complete tool environment for assisting the design of active rules applications; the tools were developed at Politecnico di Milano in the context of the IDEA Project, a 4-years Esprit project sponsored by the European Commission which was launched in June 1992. We describe tools for active rule generation, analysis, debugging, and browsing; rules are defined in Chimera, a conceptual design model and language for the specification of active rules applications. We also introduce a tool for mapping from Chimera into Oracle, a relational product supporting triggers.Most of the tools described in this paper are fully implemented and currently in operation (beta-testing) within the companies participating to the IDEA Project, with the exception of two of them (called Argonaut-V and Pandora), which will be completed by the end of 1996.Research presented in this paper is supported by Esprit project P6333 IDEA, and by ENEL contract VDS 1/94: Integrity Constraint Management 相似文献
24.
David Schleicher Luis M. Bergasa Manuel Ocaña Rafael Barea Elena López 《Robotics and Autonomous Systems》2010,58(8):991-1002
In this paper we present a new real-time hierarchical (topological/metric) Visual SLAM system focusing on the localization of a vehicle in large-scale outdoor urban environments. It is exclusively based on the visual information provided by a cheap wide-angle stereo camera. Our approach divides the whole map into local sub-maps identified by the so-called fingerprints (vehicle poses). At the sub-map level (low level SLAM), 3D sequential mapping of natural landmarks and the robot location/orientation are obtained using a top-down Bayesian method to model the dynamic behavior. A higher topological level (high level SLAM) based on fingerprints has been added to reduce the global accumulated drift, keeping real-time constraints. Using this hierarchical strategy, we keep the local consistency of the metric sub-maps, by mean of the EKF, and global consistency by using the topological map and the MultiLevel Relaxation (MLR) algorithm. Some experimental results for different large-scale outdoor environments are presented, showing an almost constant processing time. 相似文献
25.
Maria Elena Bruni Francesca Guerriero 《International Transactions in Operational Research》2010,17(2):207-220
The aim of this paper is to investigate the use of heuristic information to efficiently solve to optimality the robust shortest path problem. Starting from the exact algorithm proposed by Murty and Her, we describe how this algorithm can be enhanced by using heuristic rules and evaluation functions to guide the search. The efficiency of the proposed enhanced approach is tested over a range of random generated instances. Our computational results indicate that the use of heuristic criteria is able to speed up considerably the search and that the enhanced exact solution method outperforms the state‐of‐the‐art algorithm proposed by Murty and Her in most of the instances. 相似文献
26.
27.
A synchronizing word for a given synchronizing DFA is called minimal if none of its proper factors is synchronizing. We characterize the class of synchronizing automata having only finitely many minimal synchronizing words (the class of such automata is denoted by FG). Using this characterization we prove that any such automaton possesses a synchronizing word of length at most 3n-5. We also prove that checking whether a given DFA A is in FG is co-NP-hard and provide an algorithm for this problem which is exponential in the number of states A. 相似文献
28.
Walter Lang Frank Jakobs Elena Tolstosheeva Hannes Sturm Azat Ibragimov Antonia Kesel Dirk Lehmhus Ursula DickeAuthor vitae 《Sensors and actuators. A, Physical》2011,171(1):3-11
Ubiquitous computing is about to become part of our everyday lives by integrating hundreds of “invisible” to us computing devices in our environment, so that they can unobtrusively and constantly assist us. This will imply more and smaller “invisible” sensors, homogeneously distributed and at the same time densely packed in host materials, responding to various stimuli and immediately delivering information. In order to reach this aim, the embedded sensors should be integrated within the host material, heading towards sensorial materials. The first step is to omit all parts that are not needed for the sensorial task and to find new solutions for a gentle integration. This is what we call function scale integration. The paper discusses sensor embedding in the human hand as an example of integration in nature, new technological applications and main challenges associated with this approach. 相似文献
29.
Because of their widespread use in real-world transportation situations, hub location models have been extensively studied in the last two decades. Many types of hub location problems are NP-hard and remain unmanageable when the number of nodes exceeds 200. We present a way to tackle large-sized problems using aggregation, explore the resulting error, and show how to reduce it. Furthermore, we develop a heuristic based on aggregation for k-hub center problems and present computational results. 相似文献
30.
In this paper we consider the case of nonlinear convection-diffusion problems with a dominating convection term and we propose
exponential integrators based on the composition of exact pure convection flows. These methods can be applied to the numerical
integration of the considered PDEs in a semi-Lagrangian fashion. Semi-Lagrangian methods perform well on convection dominated
problems (Pironneau in Numer. Math. 38:309–332, 1982; Hockney and Eastwood in Computer simulations using particles. McGraw-Hill, New York, 1981; Rees and Morton in SIAM J. Sci. Stat. Comput. 12(3):547–572, 1991; Baines in Moving finite elements. Monographs on numerical analysis. Clarendon Press, Oxford, 1994).
In these methods linear convective terms can be integrated exactly by first computing the characteristics corresponding to the gridpoints of the adopted discretization, and then producing
the numerical approximation via an interpolation procedure. 相似文献