Culture supernatant of Shiga toxin-producing Escherichia coli strains provoke fluid accumulation in rabbit ileal loops

In the present study, in order to get a better insight into the mechanism of action of cyclophosphamide (CY) in rheumatoid arthritis (RA), we monitored the changes in lymphocytes' expression of leukocyte function associated antigen 1 (LFA-1). A group of 28 patients with refractory severe RA were treated with CY and methylprednisolone (MO) intravenously. Using flow cytometry we evaluated the changes in LFA-1 molecule expression on peripheral lymphocytes. In the analyzed group of patients the proportion of LFA-1 "dim" cells was reduced. After the treatment the ratio was partly normalized. Twelve months after cessation of the therapy high proportion of LFA-1 "dim" was observed only among CY/MP treated patients. The changes were related to clinical improvement. Based on the obtained data, it seems, that the treatment affecting the expression of LFA-1 may slow down lymphocyte migration and by that limit chronic inflammation within the synovium.     

Mixed Logical Dynamical Nonlinear Model Predictive Controller for Large‐Scale Solar Fields

This paper presents a control algorithm for reducing heat losses caused by clouds in large solar fields. The formulation is based on a Mixed Logical Dynamical (MLD) representation of the solar field plus the application of a Practical Nonlinear Model Predictive Controller (PNMPC) for calculating the optimal control action. The main purpose of the controller is to deactivate fields with inlet temperature greater than outlet temperature and to manipulate the oil flow rate of the activated fields for tracking the reference of the outlet temperature. A simplified lumped parameters model is used for prediction and simulation of the solar fields.     

Synthesis,surface profile,nonlinear reflective index and photophysical properties of curcumin compound

Curcumin and other three curcuminoids (bisdemethoxycurcumin, α-chlorocurcumin and α-methylcurcumin) were synthesized. Fourier transform infrared spectroscopy, Fluorescence quantum yields, AFM analysis and image surface profiles were characterized. All compounds possessed electron donor moieties at both ends of the conjugated π-system and an electron acceptor moiety in the middle of the molecules (D-A-D system) and should exhibit different optical properties depending on substituents on the benzene rings. The third order nonlinear optical properties of the curcuminoids have been investigated by z-scan technique. The optical response was characterized by measuring the refractive index (n₂) of the derivatives of curcumin using the Z-scan technique. The compounds showed negative and large nonlinear refractive index values of the order of 10^?7 cm²/W and reverse saturable absorption with high values of the nonlinear absorption coefficient of the order of 10^?4 cm/W. The nonlinear refractive index was found to vary with the different compound. The optical constants of the different compound films were studied and the dispersion of the refractive index was discussed in terms of the Wemple-DiDomenico single oscillator model. The photo-physical properties of these compounds are compared to those of native curcumin, in order to provide a rationale to the design of samples with molecular structures optimized for a photosensitizer. These types of materials may be considering new photonic applications.     

Effective and efficient similarity searching in motion capture data

Multimedia Tools and Applications - Motion capture data describe human movements in the form of spatio-temporal trajectories of skeleton joints. Intelligent management of such complex data is a...     

EMVS: Event-Based Multi-View Stereo—3D Reconstruction with an Event Camera in Real-Time

Event cameras are bio-inspired vision sensors that output pixel-level brightness changes instead of standard intensity frames. They offer significant advantages over standard cameras, namely a very high dynamic range, no motion blur, and a latency in the order of microseconds. However, because the output is composed of a sequence of asynchronous events rather than actual intensity images, traditional vision algorithms cannot be applied, so that a paradigm shift is needed. We introduce the problem of event-based multi-view stereo (EMVS) for event cameras and propose a solution to it. Unlike traditional MVS methods, which address the problem of estimating dense 3D structure from a set of known viewpoints, EMVS estimates semi-dense 3D structure from an event camera with known trajectory. Our EMVS solution elegantly exploits two inherent properties of an event camera: (1) its ability to respond to scene edges—which naturally provide semi-dense geometric information without any pre-processing operation—and (2) the fact that it provides continuous measurements as the sensor moves. Despite its simplicity (it can be implemented in a few lines of code), our algorithm is able to produce accurate, semi-dense depth maps, without requiring any explicit data association or intensity estimation. We successfully validate our method on both synthetic and real data. Our method is computationally very efficient and runs in real-time on a CPU.     

The Advantage of Nanowire Configuration in Band Structure Determination

Earth-abundant and environmentally friendly semiconductors offer a promising path toward low-cost mass production of solar cells. A critical aspect in exploring new semiconducting materials and demonstrating their enhanced functionality consists in disentangling them from the artifacts of defects. Nanowires are diameter-tailored filamentary structures that tend to be defect-free and thus ideal model systems for a given material. Here, an additional advantage is demostrated, which is the determination of the band structure, by performing high energy and spatial resolution electron energy-loss spectroscopy in aloof and inner beam geometry in a scanning transmission electron microscope. The experimental results are complemented by spectroscopic ellipsometry and are excellently correlated with first principles calculations. This study opens the path for characterizing the band structure of new compounds in a non-destructive and prompt manner, strengthening the route of new materials discovery.     

The subunit structure of human macrophage migration inhibitory factor: evidence for a trimer

The subunit structure of human macrophage migration inhibitoryfactor (MIF) has been studied by preliminary X-ray analysisof wild-type and selenomethionine-MIF and dynamic light scattering.Crystal form I of MIF belongs to space group P2₁2₁2₁ and isgrown from 2 M ammonium sulfate at pH 8.5. A native data sethas been collected to 2.4 Å resolution. Self-rotationstudies and V_m values indicate that three molecules per asymmetricunit are present A data set to 2.8 Å resolution has beencollected for crystal form II, which belongs to space groupP3¹21 or P3²21 and grows from 2 M ammonium sulfate, 2% polyethyleneglycol (average molecular mass 400), 0.1 M HEPES, pH 7.5. Three,four, five or six monomers in the asymmetric unit are consistentwith V_m values for this crystal form. Analysis of crystal formII containing selenomethionine-MIF indicates nine selenium sitesare present per asymmetric unit. Dynamic light scattering ofMIF suggests that the major form of the protein in solutionis a trimer. The results of these studies are in contrast toprevious reports indicating that MIF is a monomer or dimer.The subunit arrangement of MIF is similar to that of tumor necrosisfactor and suggests that signal transduction might require trimerizationof receptor subunits.     

Carbon black oxidation in the presence of Al2O3, CeO2, and Mn oxide catalysts: An EPR study

Carbon black oxidation in the presence of CeO₂, Al₂O₃ and manganese oxide catalysts has been studied in tight contact conditions. In the presence of manganese based catalysts, the temperature gain is about 275 °C compared to the non-catalysed carbon black oxidation. The contribution of the manganese species to enhance the reactivity of carbon black oxidation has been evaluated by EPR technique. For Mn/Ce + CB mixtures the Mn²⁺ content considerably increases consequently to tight milled treatment indicating the reduction of some manganese species with higher oxidation states into Mn²⁺ ions. This phenomenon can be considered as the first step in the carbon black oxidation mechanism in the presence of Mn/Ce catalysts.     

A 60 GHz phased array with measurement and de-embedding techniques

We present a 60 GHz phased array system that combines several key technologies to realize 10 GHz bandwidth coverage. Particularly, a tightly coupled dipole array centered at 60 GHz is designed and tested for its wideband performance. The tightly coupled dipole elements offer excellent wideband behavior of 10 GHz with voltage standing wave ratio?<?3 with scanning to 45°, as well as low cost printed circuit board fabrication. Additionally, we demonstrate a measurement setup with de-embedding procedure to measure gain at the antenna feed point. A feeding structure was designed and fabricated for de-embedding gain pattern measurements. Recovered measurements are shown to be in agreement with simulation.