Investigations of the fundamental quantum noise properties of resonant-cavity light-emitting diodes (rcleds)

We present first results of the investigations of the quantum noise properties of resonant-cavity light-emitting diodes (rcleds). We obtain a quantum noise of up to ?0.07dB below the shot noise quantum limit already at moderate pump levels and when being pumped by a quiet current source. This amount of observed sub-shot noise emission is in accordance with the quantum efficiency of the devices. This Sub-Poisson intensity noise ofrcleds together with their narrow beam characteristics make them very attractive for applications in photonics and metrology.     

Modelling of the porous anodizing of aluminium: Generation of experimental input data and optimization of the considered model

The current paper considers the interdependency between the current density, the anodic overpotential and the temperature during the porous anodizing of aluminium in a sulphuric acid electrolyte. In contrast to common anodizing experiments, a sequence of increasing current densities is applied to each electrode. As demonstrated, this anodizing approach allows evaluating stationary anodic potentials up to very high current densities without being confronted with anomalous oxide growth. Additionally, anodizing is performed at controlled electrolyte and electrode temperature. Due to its large influence on the electrochemical behaviour, the control of the electrode temperature is important when studying the temperature dependency of the process. Based on the experimental evolutions a macroscopic model is presented, describing the relation between the considered general process parameters. It is demonstrated that a relatively simple expression is capable of well describing the experimental data in the extensive range of temperatures and current densities.     

Influence of the ion bombardment of O2 plasmas on low-k materials

In this study, special tests were devised in order to investigate the influence of ion bombardment on the damage induced in low-k dielectrics by oxygen plasmas. By placing a sample that suffered a lot of ion bombardment and one which suffered little ion bombardment simultaneously in the same plasma, it was possible to verify that ion bombardment in fact helped to protect the low-k film against oxygen plasma induced damage. Exhaustive analyses (ellipsometry, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, porosimetry, capacitance-voltage (C-V) measurements, water contact angle analysis) show that ion bombardment induced the formation of a denser top layer in the film, which then hampered further penetration of active oxygen species deeper into the bulk. This was further confirmed by other tests combining capacitively and inductively coupled plasmas. Therefore, it was possible to conclude that, at least for these plasmas, ion bombardment may help to reduce plasma induced damage to low-k materials.     

Time-dependent mechanical behavior of lime-mortar masonry

An extensive experimental program has been set up to characterize the time-dependent deformation behavior of masonry, subjected to the creep failure mode. Different types of short-term creep tests were performed on small masonry specimens, which were constructed with air-hardening lime mortar. To assess the influence of the carbonation process on creep behavior, several specimens were subjected to accelerated carbonation. The time-dependent deformations are modeled using a viscoelastic, rheological model which includes damage effects. The applicability of the model is validated by comparing theoretical and experimental results and extending the time frame to long-term predictions. Good agreement was found between experimental and simulated time-dependent deformations. The accuracy of the proposed model is estimated by including the scatter on the most important material parameters in the analysis.     

Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes

Experimental tumors of the central nervous system were investigated with antibodies to quinolinate to assess the cellular distribution of this endogenous neurotoxin. In advanced F98 and RG-2 glioblastomas and E367 neuroblastomas in the striatum of rats, variable numbers of quinolinate immunoreactive cells were observed in and around the tumors, with the majority being present within tumors, rather than brain parenchyma. The stained cells were morphologically variable, including round, complex, rod-shaped, and sparsely dendritic cells. Neuroblastoma and glioma cells were unstained, as were neurons, astrocytes, oligodendrocytes, ependymal cells, endothelial cells, and cells of the choroid plexus and leptomeninges. Glial fibrillary acidic protein immunoreactivity was strongly elevated in astrocytes surrounding the tumors. Dual labeling immunohistochemistry with antibodies to quinolinate and glial fibrillary acidic protein demonstrated that astrocytes and the cells containing quinolinate immunoreactivity were morphologically disparate and preferentially distributed external and internal to the tumors, respectively, and no dual labeled cells were observed. Lectin histochemistry with Griffonia simplicifolia B4 isolectin and Lycopersicon esculentum lectin demonstrated numerous phagocytic macrophages and reactive microglia in and around the tumors whose distribution was similar to that of quinolinate immunoreactive cells, albeit much more numerous. Dual labeling studies with antibodies to quinolinate and the lectins demonstrated partial codistribution of these markers, with most double-labeled cells having the morphology of phagocytes. The present findings suggest the possibility that quinolinate may serve a functional role in a select population of inflammatory cell infiltrates during the immune response to brain neoplasms.     

Viruses and virus-like particles identified in ostrich gut contents

Several postsynaptic nondepolarizing muscle relaxants are used today mainly for maintenance of muscular relaxation in surgical operations. They possess a highly selective effect on the cholinoceptors (CC) of the skeletal muscle postsynaptic membrane. Aminosteroid derivatives are important among them. The first to be suggested was pancuronium, and later pipecurium and the monoquaternary aminosteroid derivatives vecoronium and rocuronium. Highly selective muscle relaxants are atracurium and its isomers, cisatracurium in particular, as well as some atracurium derivatives: mivacurium and doxacurium. Tercuronium also has a highly selective effect on the CC of the skeletal muscles.     

Study on the precision of the multiaperture scintillation sensor turbulence profiler (MASS) employed in the site testing campaign for the Thirty Meter Telescope

The multiaperture scintillation sensor (MASS) has become a device widely employed to measure the altitude distribution of atmospheric turbulence. An empirical study is reported that investigates the dependence of the MASS results on the knowledge of the instrumental parameters. Also, the results of a side-by-side comparison of two MASS instruments are presented, indicating that MASS instruments permit measurements of the integrated seeing to a precision better than 0.05 arc sec and of the individual turbulence layer strength C(n)(2)(h)dh to better than 10(-14) m(1/3).     

Biocompatibility and biodegradability of spider egg sac silk

Spider egg sac silk (SpESS) were enzymatically cleaned and their biodegradation in vivo and in vitro, as well as their biocompatibility were studied. Proteinase K treatment diminished the tenacity and the strain of the SpESS fibers in proportion to the enzyme concentration. Fibers treated with trypsin were not significantly affected. Tensile properties of Vicryl, SpESS and of silkworm (Bombyx mori) silk fibers (SWS) were measured after incubation in phosphate buffered saline (PBS) at 37 degrees C up to 12 weeks. Biodegradation of SpESS and SWS was insignificant compared to Vicryl. Five milligram SpESS fibers from laboratory grown spiders (Araneus diadematus) were treated with proteinases before sterilization and subcutaneously implanted in Wistar rats. After 1, 4 and 7 weeks the immunological reaction was compared to untreated SpESS and polyglactin (Vicryl) control samples. SpESS samples treated with trypsin only or in combination with a Proteinase K treatment induced less inflammatory reactions than untreated silk fibers. The enzymatical cleaning could diminish the tensile properties, but enhanced the biocompatibility of the SpESS fibers rendering them appropriate for use in biomaterial application where the slow biodegradability is an advantage.     

Silkworm and spider silk scaffolds for chondrocyte support

Objective To create scaffolds with silkworm cocoon, spider egg sac and spider dragline silk fibres and examine their use for chondrocyte attachment and support. Methods Three different kinds of scaffolds were developed with Bombyx mori cocoon, Araneus diadematus egg sac and dragline silk fibres. The attachment of human articular cartilage cells were investigated on these bioprotein matrices. The chondrocytes produced an extracellular matrix which was studied by immunostaining. Moreover, the compression behaviour in relation to the porosity was studied. Results The compression modulus of a silkworm silk scaffold was related to its porosity. Chondrocytes were able to attach and to grow on the different fibres and in the scaffolds for several weeks while producing extracellular matrix products. Conclusion Porous scaffolds can be made out of silkworm and spider silk for cartilage regeneration. Mechanical properties are related to porosity and pore size of the construct. Cell spreading and cell expression depended on the porosity and pore-size.