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排序方式: 共有316条查询结果,搜索用时 31 毫秒
301.
Alessandro Passardi Emanuela Scarpi Paola Ulivi 《International journal of molecular sciences》2021,22(14)
The present editorial aims to summarise the six scientific papers that have contributed to this Special Issue, focusing on different aspects of molecular and translational research on colorectal cancer. We believe that the present Special Issue might contribute to the expansion of the current knowledge concerning potential molecular predictive and/or prognostic biomarkers in CRC, as well as new targets for anticancer treatment. This may help in identifying new strategies to improve diagnostic and therapeutic approaches. 相似文献
302.
303.
Vitale F Fratoddi I Battocchio C Piscopiello E Tapfer L Russo MV Polzonetti G Giannini C 《Nanoscale research letters》2011,6(1):103
Stable gold nanoparticles stabilized by different mono and bi-functional arenethiols, namely, benzylthiol and 1,4-benzenedimethanethiol,
have been prepared by using a modified Brust's two-phase synthesis. The size, shape, and crystalline structure of the gold
nanoparticles have been determined by high-resolution electron microscopy and full-pattern X-ray powder diffraction analyses.
Nanocrystals diameters have been tuned in the range 2 ÷ 9 nm by a proper variation of Au/S molar ratio. The chemical composition
of gold nanoparticles and their interaction with thiols have been investigated by X-ray photoelectron spectroscopy. In particular,
the formation of networks has been observed with interconnected gold nanoparticles containing 1,4-benzenedimethanethiol as
ligand. 相似文献
304.
D'Agostino A Errico ME Malinconico M De Rosa M Avella M Schiraldi C 《Journal of materials science. Materials in medicine》2011,22(3):481-490
In this research work organic/inorganic nano composites were synthesized from poly-2-hydroxyethylmethacrylate and properly
modified silica nanoparticles by in situ polymerization. In particular, fumed nanosilica was functionalized with methacryloylpropyltrimetoxy
silane (MPTMS) in order to obtain a more homogeneous, reliable and mechanically performing nano composite. For comparison,
nano composites with non functionalised silica were also prepared. Scanning electron microscopy was performed in order to
visualize the effects of functionalization on the mode and state of dispersion. This analysis demonstrated that MPTMS grafted
onto silica surface acts as an effective coupling agent and assures a good dispersion and distribution of nanoparticles as
well as a strong nano particle/matrix interfacial adhesion. As a result of strong interactions occurring between phases, a
pronounced increase of the glass transition temperature and mechanical parameters were recorded. Finally, these novel nano
composites were seeded with murine fibroblast and human mesenchymal stem cells, and observed in time-lapse experiments proving
an effective biological response. 相似文献
305.
306.
Emanuela Callone Julia M. Fletcher Giovanni Carturan Rishi Raj 《Journal of Materials Science》2008,43(14):4862-4869
We show that thin films of silica loaded with 22 wt% of carbon nanotubes (CNTs) can be deposited on cellulose substrate via
the sol–gel route by a well-controlled process. The high loadings are obtained by airbrush spraying of a diluted sol solution (which contained a much smaller concentration of CNTs) followed by drying at 200 °C. The films are nearly continuous
despite the fibrous structure of the substrate. The high degree of connectivity of the stranded structure of the CNTs yields
a specific electrical conductivity of 3 × 103 Ω−1 m−1. In contrast, films made with high loadings of carbon black have poor electrical conductivity. Results from mechanical tensile
tests of samples are also reported. This economical method of producing CNT dispersed thin films could find application in
catalysis, as electrodes in fuel cells and batteries, and in sensor technologies. 相似文献
307.
Torelli E Firrao G Bianchi G Saccardo F Locci R 《Journal of the science of food and agriculture》2012,92(8):1808-1814
BACKGROUND: Contamination by mycotoxins is a major concern to the maize industry in north‐east Italy where maize grain is often spoiled by Fusarium spp. In this work, fumonisins, deoxynivalenol and zearalenone were determined and an artificial neural network (ANN) model suitable for predicting mycotoxin contamination of maize at harvest time was developed. RESULTS: The occurrence of deoxynivalenol and zearalenone was very limited, while fumonisins concentration ranged from 163 and to 3663 µg kg?1 in 2007, and from 333 to 11473 µg kg?1 in 2008. Statistical data analysis of factors affecting fumonisins concentration revealed that irrigation, chemical treatment against the European corn borer and harvest date significantly affected the level of contamination (P < 0.05), although the relevance of the factors was different in 2007 and 2008. The neural network approach showed a significant correlation between ascertained values and predictions based on agronomic data. CONCLUSION: This is the first time that an artificial neural network has been used to predict fumonisin accumulation in maize: the prediction has been shown to have the potential for the development of a new approach for the rapid cataloging of grain lots. Copyright © 2012 Society of Chemical Industry 相似文献
308.
Sn, Sn-Sb, Ti, Zr, Fe, Ce and In oxides are prepared as nanometric powders by the hydrolytic route, starting from their ordinary salts or alkoxides, in the presence of 5% w/v starch as a non-ionic stabilizer of crystallization nuclei versus coalescence and flocculation. The starch can be degraded by a-amylase to soluble glucosidic oligomers, which may further be degraded by yeast to CO2 and ethanol. The nanoparticle features of prepared oxides result from experimental evidence based on X-ray diffractometry, transmission electron microscopy, differential thermal analysis/thermogravimetry coupled to mass spectrometry, specific surface area and porosity of samples obtained by curing in the 80-600 degrees C interval. 相似文献
309.
Emanuela Alessandra Greco Cristina Antinozzi Luigi Di Luigi Antonio Aversa Paolo Sgr 《International journal of molecular sciences》2022,23(8)
Tadalafil is a selective phosphodiesterase type-5 (PDE5) inhibitor that is approved for the treatment of men with erectile dysfunction (ED) and/or benign prostate hyperplasia (BPH) -associated symptoms. Besides its classical actions on PDE5 within the genitourinary tract, where the specific enzyme expression is maximal, it may exert different systemic effects. This is mainly due to the pleiotropic distribution of PDE5 enzyme throughout the human (and animal) body, where it can exert protective effects in different clinical conditions. Recently, it has been demonstrated that tadalafil may display novel actions on androgen receptor (AR) expression and activity and cytochrome P19a1 (Cyp19a1) and estrogen receptor β (ERβ) expression in different in vitro systems, such as adipose, bone and prostate cancer cells, where it can act as a selective modulator of steroid hormone production. This may determine novel potential mechanism(s) of control in pathophysiologic pathways. In this review, we summarize basic research and translational results applicable to the use of tadalafil in the treatment of obesity, bone loss and prostate cancer. 相似文献
310.
The influence of inulin addition on the morphological and structural properties of durum wheat pasta 总被引:1,自引:0,他引:1
Daniela Manno Emanuela Filippo Antonio Serra Carmine Negro Luigi De Bellis & Antonio Miceli 《International Journal of Food Science & Technology》2009,44(11):2218-2224
The effect of the addition of different concentration of inulin fibre to durum wheat pasta was evaluated in terms of structure, texture and morphological characteristics. Inulin fibre fraction was incorporated into pasta at 5%, 10% and 15% inclusion rates. Changes to pasta quality were observed with inulin fibre fraction addition by scanning electron microscopy, X-ray diffraction and Raman spectroscopy methods. Investigation of pasta microstructure indicate a lowering in crystallinity increasing the inulin content and characterisation of starch gelatinisation events indicated that a combination of changes to the starch–protein matrix and the high water-binding capacity of inulin alters the physico-chemical properties and then the digestibility of the pastas. 相似文献