Evaluation of a commercial process for collection and cooling of beef offals by a temperature function integration technique.

The hygienic adequacy of a commercial process for the collection and cooling of beef offals was assessed by a temperature function integration technique. The diverse operations for collection of offals were inspected. The rates of product movement through those operations, and the temperatures of products at the time of their being packed, were determined. From that information, four of the nine product types were selected for examination of their temperature histories during the assembly and cooling of the cartoned products. The products selected encompassed product at near-body and near-air-ambient temperatures at the time of packaging, product in the largest and smallest cartons used in the process, and product with relatively short and long residence times in an unchilled carton stack assembly area. Twenty-one temperature histories were collected for each of the products, and the possible proliferation of an indicator organism, Escherichia coli, calculated for each temperature history. The results were assessed against a temperature function integration criterion derived from studies of beef carcass and cartoned meat cooling processes. Products packaged at near-ambient temperature readily met with the criterion, but products packed at near-body temperatures did not comply. The latter non-compliance was extreme for product packaged in large cartons. However, the principal cause of non-compliance was identified as highly variable cooling conditions in the carton freezing facility. A brief survey of air speeds and temperatures within that facility indicated means by which product cooling could be better controlled.     

Effects of a quick-release form of bromocriptine (Ergoset) on fasting and postprandial plasma glucose, insulin, lipid, and lipoprotein concentrations in obese nondiabetic hyperinsulinemic women

OBJECTIVE: To assess the effect on various aspects of carbohydrate and lipid metabolism of administering a quick-release formulation of bromocriptine (Ergoset) to obese, nondiabetic, hyperinsulinemic women. RESEARCH DESIGN AND METHODS: Hourly concentrations of prolactin, glucose, insulin, free fatty acid (FFA), and triglyceride were measured for 24 h before and after approximately 8 weeks of treatment with Ergoset. In addition, fasting lipid and lipoprotein concentrations and the steady-state plasma glucose (SSPG) concentration in response to a continuous infusion of somatostatin, insulin, and glucose were determined before and after Ergoset administration. RESULTS: Circulating prolactin concentrations were dramatically decreased (P < 0.001) following treatment, associated with a significant fall (P < 0.05) in 24-h-long plasma glucose, FFA, and triglyceride concentrations. Neither circulating plasma insulin concentrations nor the ability of insulin to mediate glucose disposal changed with treatment. Finally, fasting total cholesterol fell (P < 0.05) and the ratio of total to HDL cholesterol decreased (P = 0.06) in association with Ergoset treatment. CONCLUSIONS: The fact that significant metabolic improvement was seen in the obese nondiabetic hyperinsulinemic women studied suggests that Ergoset could be of therapeutic benefit in clinical conditions of hyperglycemia and/or dyslipidemia.     

Antimicrobial activity and spectrum of LB20304, a novel fluoronaphthyridone

Compound LB20304 is a fluoronaphthyridone carboxylic acid with a novel pyrrolidine substituent. This drug was compared with ciprofloxacin, levofloxacin, ofloxacin, and trovafloxacin against over 800 pathogens, most from blood stream infections, by National Committee for Clinical Laboratory Standards reference methods. LB20304 was the most active agent against gram-positive species including strains observed to be resistant to other fluoroquinolones and glycopeptides. The potency of LB20304 (MIC50, 0.03 micrograms/ml) against the Enterobacteriaceae was exceeded only by that of ciprofloxacin (0.015 micrograms/ml). It has limited activity against gram-negative anaerobes.     

Atmospheric Chemistry of 2-Ethyl Acrolein

The atmospheric oxidation of the unsaturated aldehyde 2-ethyl acrolein, CH₂=C(C₂H₅)CHO, has been studied in laboratory experiments involving the reaction of ozone with 2-ethyl acrolein in the dark (with cyclohexane added to scavenge the hydroxyl radical), and the sunlight irradiation of 2-ethyl acrolein with NO in air. The major carbonyl products of the 2-ethyl acrolein reaction with ozone are formaldehyde, acetaldehyde, and the dicarbonyl ethylglyoxal, CH₃CH₂COCHO. Sunlight irradiation of 2-ethyl acrolein and NO led to the formation of three carbonyls (formaldehyde, acetaldehyde, and ethylglyoxal) and three peroxyacyl nitrates, (RC(O)OONO₂), including PAN (R = CH₃), PPN (R = C₂H₅), and the unsaturated compound EPAN (R = CH₂=C(C₂H₅)). Mechanisms are outlined for the reactions of ozone and of the hydroxyl radical with 2-ethyl acrolein. These mechanisms are consistent with the observed carbonyl and peroxyacyl nitrate products. Thermal decomposition, a major atmospheric removal process for peroxyacyl nitrates, has been studied for EPAN. The decomposition rate of EPAN relative to that of PAN is 0.59–0.73 at 292–294 K and 1 atm of air. Atmospheric implications of these results are discussed.     

Activity of NiO in (Ni,Mg)O Solid Solutions

Disagreement exists in the literature concerting the activity of NiO in (Ni,Mg)O solid solutions. Ideal behavior, as well as strong positive deviations and strong negative deviations from ideality, has been reported. In the present study, the activity of NiO was determined by electromotive force measurements using the solid-state cell Pt/Ni-NiO/0.92ZrO₂-0.08Y₂O₃/Ni-(Ni,Mg)O/Pt. The compositions studied had NiO mole fractions of 0.1,0.3,0.5,0.7, and 0.9. In agreement with theoretical expectations, the solid solutions exhibited ideal behavior at 882° and 982°C. Possible reasons for the conflicting results in the literature arc presented.     

Influence of low-frequency electromagnetic fields on living organisms

Recent research reports appear to indicate a real possibility that the low-frequency electromagnetic field produced by the power transmission and distribution network presents a health problem. A critical assessment of the available information is presented here. The state of knowledge, available evidence and conflicting reports indicate a definite need for interim action by the power industry. New direction for analytical research, possible interim avoidance measures, proper advice to clients and the public are discussed. Detailed mathematical modeling for the linear and nonlinear dynamics of DNA and the chromosome as a whole is suggested.     

Determination of tryptophan in feedstuffs: Comparison of two methods of hydrolysis prior to HPLC analysis

The tryptophan content of nine samples of commercial feed was determined using two procedures (I and II) differing mainly in the hydrolysis conditions used prior to analysis. With I, hydrolysis was performed with 4 M LiOH in the presence of maltodextrin with 5-methyltryptophan used as internal standard at 110°C for 24 h; with II. oxygen-free 1.3 M Ba(OH)₂ was used at 125°C for 16 h. The two procedures gave identical results for a given sample indicating that the corrections for the incomplete recovery of tryptophan 5-methyltryptophan quantitation were satisfactory.     

Tracking musical patterns using joint accent structure.

Joint Accent Structure (JAS) is a construct that uses temporal relationships between different accents in a melodic pattern as indices of its complexity. The present study examines the role of different JASs in real time, attending to simple musical events. 39 adults with or without musical training were told to selectively attend to and synchronize finger taps with accents in 2 experiments that examined attentional tracking to musical patterns having a concordant or discordant JAS. Results indicate that tapping was more variable with discordant than with concordant JAS patterns, both with respect to produced inter-accent time periods and with respect to the phase of taps relative to accent onsets. These findings are interpreted in terms of real time attending and its control by event time structure. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Mixing and solid-liquid mass-transfer rates in a creusot-loire uddeholm vessel: A water model case study

The process of mixing and solid-liquid mass transfer in a one-fifth scale water model of a 100-ton Creusot-Loire Uddeholm (CLU) converter was investigated. The modified Froude number was used to relate gas flow rates between the model and its protoype. The influences of gas flow rate between 0.010 and 0.018 m³/s and bath height from 0.50 to 0.70 m on mixing time were examined. The results indicated that mixing time decreased with increasing gas flow rate and increased with increasing bath height. The mixing time results were evaluated in terms of specific energy input and the following correlation was proposed for estimating mixing times in the model CLU converter: T _mix=1.08Q ^−1.05 W ^0.35, where Q (m³/s) is the gas flow rate and W (tons) is the model bath weight. Solid-liquid mass-transfer rates from benzoic acid specimens immersed in the gas-agitated liquid phase were assessed by a weight loss measurement technique. The calculated mass-transfer coefficients were highest at the bath surface reaching a value of 6.40 × 10⁻⁵ m/s in the sprout region. Mass-transfer coefficients and turbulence parameters decreased with depth, reaching minimum values at the bottom of the vessel.