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51.
Endothelial cell-matrix interactions   总被引:1,自引:0,他引:1  
Dynamic interactions between endothelial cells and components of their surrounding extracellular matrix are necessary for the invasion, migration, and survival of endothelial cells during angiogenesis. These interactions are mediated by matrix receptors that initiate intracellular signaling cascades in response to binding to specific extracellular matrix molecules. The interactions between endothelial cells and their environment are also modulated by enzymes that degrade different matrix components and thus enable endothelial invasion. Recent reports on gene targeting in mice have confirmed the role of two classes of matrix receptors, integrins and cell surface heparan sulfate proteoglycans, and a group of matrix degrading proteolytic enzymes, matrix metalloproteinases, in angiogenesis. The significance of endothelial cell-matrix interactions is further supported by several ongoing clinical trials that analyze the effects of drugs blocking this interaction on angiogenesis-dependent growth of human tumors.  相似文献   
52.
The use of TV white spaces as an alternative to overcome spectrum scarcity is a huge opportunity for new telecommunication systems and services. While being attractive for its desirable propagation characteristics, this part of the spectrum imposes a major difficulty from design and regulatory perspectives: how to optimize the use of spectrum and to ensure the protection of primary users, TV systems for example, at the same time. This paper discusses strategies to be adopted by geo-location database operators to calculate adaptive maximum permitted power levels for secondary devices, according to permissible levels of interference into the digital terrestrial television primary system.  相似文献   
53.
Many U.S. adults hold fatalistic beliefs about cancer prevention despite evidence that a large proportion of cancer deaths are preventable. We report findings from two studies that assess the plausibility of the claim that local television (TV) news cultivates fatalistic beliefs about cancer prevention. Study 1 features a content analysis of an October 2002 national sample of local TV and newspaper coverage about cancer. Study 2 describes an analysis of the 2005 Annenberg National Health Communication Survey (ANHCS). Overall, findings are consistent with the claim that local TV news coverage may promote fatalistic beliefs about cancer prevention. We conclude with a discussion of study implications for cultivation theory and the knowledge gap hypothesis and suggest foci for future research.  相似文献   
54.
根据本发明,该水处理组成物是一种有效抑制腐蚀和生物腐蚀过程的组成物。作为一种缓蚀剂,其含有一种或多种氨基和/或羟甲基化单或聚合磷酸,其作为缓蚀剂显示出系统效应,可以是羟甲基化氨基酸、嘌呤衍生物、不饱和芳香剂和碳酸,稠芳香化合物(苯和甲基苯三唑衍生物)、水溶性聚合物和无机磷酸盐衍生物,作为生物缓蚀剂,  相似文献   
55.
A mathematical heat flow model has been developed to quantify the influence of out-of-stack time and other variables on the temperature distribution in the refractory wall of copper converters. Factors such as diameter of the converter, size and position of the converter mouth, and the use of a mouth cover have been studied with the model, in order to relate converting practice to operating problems. The results of the model indicate that when the converter is out of the stack, heat losses through the mouth of the converter cause the internal refractory surface to cool rapidly which may lead to freezing at the tuyere line and tuyere blockage when blowing is resumed. The temperature gradient, localized to within 60 to 80 mm of the refractory inside wall, changes markedly within the first minutes of the converter being out of the stack. This may generate thermal stresses in the converter wall and contribute to refractory erosion at the tuyere line. Covering the converter mouth during out-of-stack periods significantly reduces the change in temperature gradient at the inside wall as well as heat losses from the converter. Formerly Graduate Student  相似文献   
56.
A solutionizing heat treatment of 2014 aluminum alloy reinforced with 0.15 volume fraction of alumina particles (VFAP) results in deformation-induced precipitation during rolling and tensile deformation, with 0.10 VFAP, at room temperature. The extent of precipitation increases with increase in time and/or temperature of solutionizing. An attempt has been made to identify the various types of precipitates in the samples deformed to a given strain and in fractured conditions. The work-hardening curves and tensile properties of the composites have been shown to be dependent on the time and temperature combination of the solutionizing process.  相似文献   
57.
High porosity and intense galvanic function related low electrolytic barrier profile and fast delamination of zinc-rich paints (ZRPs) are addressed by the utilisation of intimately structured, highly dispersed, polypyrrole (PPy) deposited alumina particles (PDAPs) embedded zinc-rich hybrid paints. The more globular but less-packed structure type PPy-contained water-solvent-prepared PDAPs-composited hybrids comprising spherical zinc pigment at 70 wt.%, provided moderate galvanic function with enhanced electrolytic barrier properties. In addition, the less globular structured but well-packed PPy-comprised aqueous ethanol-solvent-prepared PDAPs-composited hybrid coatings indicated highly efficient suppressed galvanic function and improved barrier properties, realising solid performance improvement over conventional ZRPs in immersion and salt-spray chamber tests. Furthermore, the application of highly dispersed PDAPs at a content of 3.2 wt.% while PPy incorporated into zinc-rich hybrids at 0.16 wt.% is proposed to result in emerging additional functionalities increasing long-term anticorrosive performance of ZRPs by inhibiting sacrificial and self-corrosion of zinc and scavenging oxidative radicals thereby hindering oxidative degradation of the organic binder.  相似文献   
58.
In an experiment exploring the impact of sound on sensations of telepresence, 126 participants watched a video clip using either headphones or speakers. The results illustrate that sound is an important factor in stimulating telepresence responses in audiences. Interactions between soundscape and screen size were also revealed. A traverse interaction between aural/visual congruency and soundscapes was evident. A second data set of 102 participants was collected to illuminate the effect of technological expectation that emerged in the first study. Expectations had been mentioned in other studies, and the data support the notion that people have an expectation of the technological quality of a presentation. The results suggest that examining expectations could assist in future conceptualizations of telepresence.  相似文献   
59.
A growing interest has been focused on silicon on insulator (SOI) technologies over the past years. Yet, few studies were carried out regarding the integration of vertical SiGe heterojunction bipolar transistors (HBTs) using such substrates. This paper deals both with the integration of a SiGeC HBT on thin-film CMOS-compatible SOI, and a comprehensive study of its electrical behavior based on physical simulation and electrical characterization. Various aspects of the optimization of device performances are described, considering process or layout improvements.  相似文献   
60.
In five studies, the authors examined the effects on cognitive performance of coherence and incoherence between conceptual and experiential sources of affective information. The studies crossed the priming of happy and sad concepts with affective experiences. In different experiments, these included approach or avoidance actions, happy or sad feelings, and happy or sad expressive behaviors. In all studies, coherence between affective concepts and affective experiences led to better recall of a story than did affective incoherence. The authors suggest that the experience of such experiential affective cues serves as evidence of the appropriateness of affective concepts that come to mind. The results suggest that affective coherence has epistemic benefits and that incoherence is costly in terms of cognitive performance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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