The effect of axial pressure gradient on extruder mixing characteristics

Many twin screw extruders are operated in the starve-fed mode with the majority of the extruder having partially-filled channels. There will always be regions of totally filled channels due to the presence of the die or reverse elements. The authors experimentally show the effect of the change of percent drag flow on the rate of distributive mixing in the co-rotating and counter-rotating twin screw extruder. Optimum operating conditions for distributive mixing are identified experimentally and verified theoretically.     

15 years of processing and dissemination of SPOT-VEGETATION products

Throughout the VEGETATION programme, the Flemish Institute for Technological Research (VITO) uninterruptedly hosted the prime user segment of both VEGETATION 1 and VEGETATION 2 multispectral instruments on board the Satellite Pour l’Observation de la Terre 4 (SPOT 4) and SPOT 5 satellites. Operational since the launch of SPOT 4 in March 1998, and foreseen to continue at least until the end of the SPOT 5 mission (anticipated in spring 2014), this user segment comprises a processing facility (PF), actively receiving, processing, correcting, archiving, and distributing the VEGETATION data and derived added-value products. First and foremost, the VEGETATION programme has been serving the needs of operational users – both institutional and commercial – requesting data in near-real time. However, scientific and educational users too benefited significantly, in particular from VEGETATION’s unique time series of the Earth’s land cover, and more specifically the vegetation cover. Over the years, the centralized archive houses processed data covering the equivalent of 11,000 times the Earth’s surface, and delivered more than 50 terapixels to around 10.000 users. As such, VEGETATION’s mission is a prime example of what Europe wants to achieve through the Global Monitoring for Environment and Security (GMES) initiative: truly operational services providing reliable and up-to-date information.

This article describes the processing facility, the way the data and products are archived, the different dissemination channels as well as the data policy adopted and the users served. One of the recent evolutions, the development of an entirely new product distribution facility (PDF), implemented as part of the Project for On-Board Autonomy – Vegetation (PROBA-V) user segment is discussed.     

Is the particle deposition in a cell exposure facility comparable to the lungs? A computer model approach

Abstract

Cell exposure experiments at the air-liquid interface (ALI) are used increasingly as indicators for health effects and for the impact of aerosols on the lung. Thereby the aerosol particles are kept airborne and can deposit on a cell surface area similar to the human respiratory tract (RT). However, geometry and air flow rates of an ALI system deviate considerably from the RT. As the tissue-delivered particle dose to the lungs (TD) can hardly be measured, computer models of particle deposition are used here to mimic both the particle deposition at ALI and in the RT. An ALI exposure setup (VitroCell GmbH) for an airflow rate of 100 cm³ min^?1 is selected, where the particle deposition model has been verified experimentally. For the RT we use the hygroscopic lung deposition model of Ferron et al. (2013 Ferron, G. A., S. Upadhyay, R. Zimmermann, and E. Karg. 2013. Model of the deposition of aerosol particles in the respiratory tract of the rat. II. Hygroscopic particle deposition. J. Aerosol Med. Pulm. Drug Deliv. 26 (2):101–19. doi:10.1089/jamp.2011.0965.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Model runs are performed for the particle deposition and for the deposited particles per surface area in both the ALI and the RT. The results show that the ALI-deposited mass is 1-2 orders of magnitude higher than in the alveolar region, because the surface area of the lung region is substantially larger. A particle size range from 40 to 450 nm is identified, where the ratio of both the deposition in a lung region and the deposition at the ALI varies by a factor less than two. Mean values for this ratio are 31 and 101 for the tracheo-bronchial and the alveolar region, respectively. The same size range is found for the ratio of the deposited particles per surface area in a lung region and at the ALI. For this range the mean surface deposition at the ALI is 23- and 1575-times larger than in the tracheo-bronchial and the alveolar lung region, respectively. The effect is partly compensated by different flow rate and cell size.

Copyright © 2020 American Association for Aerosol Research     

Measurement of birefringence for optical recording of disk substrates

We experimentally investigate the birefringence of bare and coated substrates for magneto-optical recording, using ellipsometry at wavelengths of 632.8 and 780 nm. The polarization rotation and ellipticity of reflected or transmitted light are measured for different incident angles and for different orientations of the incident linear polarization. The measured data are then fitted by the MULTILAYER computer program, which solves the Maxwell equations for a plane wave propagating in a multilayer structure. This approach makes it possible to determine, with high accuracy, the orientations of the principal axes of the substrate and the corresponding refractive indices. The results show that one of the principal axes is always along the substrate's normal direction, but the orientations of the in-plane principal axes can be much different from the radial and track directions. A special feature of the ellipsometers that were used is that a glass hemisphere is placed in contact with the substrate to eliminate refraction of the incident beam. This enables a maximum propagation angle of 70° (with respect to the normal) in the substrate and hence increases the measurement sensitivity. Certain anomalies have been observed, which we believe are associated with the variation of birefringence properties along the thickness direction.     

Retroreflecting ellipsometer for measuring the birefringence of optical disk substrates

A retroreflecting ellipsometer has been constructed for measuring the birefringence of optical disk substrates. In contrast to conventional ellipsometers with two mechanical arms, this system has only one arm along which both the incident and reflected beams travel. This construction eliminates the mechanical limitations of conventional ellipsometers, thereby permitting normal incidence on the sample. In addition, the single arm is adjustable in two dimensions, with the polar incident angle, θ(inc), varying from 0° to 70°, and the azimuthal incident angle, Φ(inc), varying from 0° to 360°. The condition of normal incidence permits accurate measurement of in-plane birefringence. The adjustability of both θ(inc) and Φ(inc) is necessary for the measurement of possible tilts of the index ellipsoid, and also for the variation of birefringence through the substrate thickness. Measurement results showing the useful features of the equipment are presented. The optics of the hemispherical assembly used for retroreflection as well as for the elimination of undesirable refractions are also studied by use of the ZEMAX lens design program.     

Adherence rates to ferric citrate as compared to active control in patients with end stage kidney disease on dialysis

Introduction: Oral phosphate binders are the main stay of treatment of hyperphosphatemia. Adherence rates to ferric citrate, a recently approved phosphate binder, are unknown. Methods: We conducted a post‐hoc analysis to evaluate whether adherence rates were different for ferric citrate vs. active control in 412 subjects with end stage kidney disease (ESKD) who were randomized to ferric citrate vs. active control (sevelamer carbonate and/or calcium acetate). Adherence was defined as percent of actual number of pills taken to total number of pills prescribed. Findings: There were no significant differences in baseline characteristics including gender, race/ethnicity, and age between the ferric citrate and active control groups. Baseline phosphorus, calcium, and parathyroid hormone levels were similar. Mean (SD) adherence was 81.4% (17.4) and 81.7% (15.9) in the ferric citrate and active control groups, respectively (P = 0.88). Adherence remained similar between both groups after adjusting for gender, race/ethnicity, age, cardiovascular disease (CVD), and diabetic nephropathy (mean [95% CI]: 81.4% [78.2, 84.6] and 81.5% [77.7, 85.2] for ferric citrate and active control, respectively). Gender, race/ethnicity, age, and diagnosis of diabetic nephropathy did not influence adherence to the prescribed phosphate binder. Subjects with CVD had lower adherence rates to phosphate binder; this was significant only in the active control group. Discussion: Adherence rates to the phosphate binder, ferric citrate, were similar to adherence rates to active control. Similar adherence rates to ferric citrate are notable since tolerance to active control was an entry criteria and the study was open label. Gender, race/ethnicity, nor age influenced adherence.     

Betriebsinformatik und Wirtschaftsinformatik als notwendige anwendungsbezogene Ergänzung einer allgemeinen Informatik – Vorschläge zur Verbesserung der akademischen Ausbildung auf dem Gebiet der automatisierten Datenverarbeitung in der Bundesrepublik Deutschland

Zusammenfassung  Nachdruck eines Aufsatzes aus elektronische datenverarbeitung 11(11)1969:544–548. This article is also available in English via and : Grochla E (2008) Corporate Information Systems Engineering and Business and Information Systems Engineering as a Necessary Application-Oriented Extension of General Computer Science – Proposals for Enhancing Academic Education in the Field of Automated Data Processing in the Federal Republic of Germany. Bus Inf Syst Eng. doi .

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Exploring US Business Cycles with Bivariate Loops Using Penalized Spline Regression

The phrase business cycle is usually used for short term fluctuations in macroeconomic time series. In this paper we focus on the estimation of business cycles in a bivariate manner by fitting two series simultaneously. The underlying model is thereby nonparametric in that no functional form is prespecified but smoothness of the functions are assumed. The functions are then estimated using penalized spline estimation. The bivariate approach will allow to compare business cycles, check and compare phase lengths and visualize this in forms of loops in a bivariate way. Moreover, the focus is on separation of long and short phase fluctuation, where only the latter is the classical business cycle while the first is better known as Friedman or Goodwin cycle, respectively. Again, we use nonparametric models and fit the functional shape with penalized splines. For the separation of long and short phase components we employ an Akaike criterion.     

Detecting improvement using Shewhart attribute control charts when the lower control limit is zero

In this paper, we present a method to monitor count data so as to be able to detect improvement when the counts are low enough to cause the lower limit to be zero. The method, which is proposed as an add-on to the conventional Shewhart control chart, consists in counting the number of samples in which zero defectives or zero defects per unit occur and signaling an increase in quality if k-in-a-row or 2-in-t samples have zero counts of defectives or zero defects per unit. This method enjoys some similarities to the very popular Shewhart control chart in that it is easy to design, understand and use. It is flexible, robust, and, like the Shewhart chart, yields detection frequencies that are optimal for very large shifts and good for other shifts. Some comparisons with traditional CUSUM charts are provided. Figures enabling Shewhart control chart users to easily design low-side add-on control charts are given for c and np charts.