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排序方式: 共有643条查询结果,搜索用时 0 毫秒
621.
Jos Miguel Rivera-Caravaca Anny Camelo-Castillo Inmaculada Ramírez-Macías Pablo Gil-Prez Cecilia Lpez-García María Asuncin Esteve-Pastor Esteban Orenes-Piero Antonio Tello-Montoliu Francisco Marín 《International journal of molecular sciences》2021,22(13)
Peripheral artery disease (PAD) is a major cause of morbidity and mortality but it is usually underdiagnosed and undertreated. Patients with PAD present dysregulated procoagulant, anticoagulant, and fibrinolytic pathways leading to arterial and venous thrombosis. The risk of several ischemic-related complications could be mitigated with appropriate antithrombotic therapy, which plays a central role in all types of PAD. For years, antiplatelets have been indicated in patients with symptomatic PAD or those who have undergone revascularization. Unfortunately, a non-negligible proportion of patients with PAD will suffer from adverse events during the follow-up, even despite proper medical therapies for the prevention of PAD complications. Thus, there is room for improving clinical outcomes in these patients. Given the implication of both, primary and secondary hemostasis in arterial thrombosis and the pathophysiology of PAD, the combination of antiplatelets and anticoagulants has emerged as a potential antithrombotic alternative to antiplatelets alone. In this narrative review article, we have highlighted the most recent evidence about antithrombotic therapy in PAD patients, with a special focus on oral anticoagulation. Certainly, COMPASS and VOYAGER PAD trials have shown promising results. Thus, rivaroxaban in combination with aspirin seem to reduce cardiovascular outcomes with a similar bleeding risk compared to aspirin alone. Nevertheless, results from real-world studies are needed to confirm these observations, and other trials will provide novel evidence about the safety and efficacy of emerging anticoagulant agents. 相似文献
622.
González-García J Cordero-Dávila A Luna E Núñez M Ruiz E Salas L Cabrera-Peláez VH Cruz-González I Sohn E 《Applied optics》2004,43(18):3623-3631
A new tool for hydrodynamic radial polishing, HyDra, allows for the local polishing of optical surfaces with a controllable wear rate. The results of the removal rate for different polisher types and sizes, applied air pressures for slurry expulsion, and tool height with respect to the working surface, are reported. We present a numerical analysis of the volumetric removal rate for the dynamic experiments as well as a comparison with a similar technique. 相似文献
623.
624.
Russo Nancy F.; Olmedo Esteban L.; Stapp Joy; Fulcher Robert 《Canadian Metallurgical Quarterly》1981,36(11):1315
Presents results from the American Psychological Association's 1978 Human Resources Survey, the 1980–1981 Survey of Graduate Departments of Psychology, and the 1972–1980 surveys of doctorate recipients from the National Research Council. In addition to overall level of representation of women and minorities, a number of other important variables are examined (e.g., subfield specialty, degree level, years of experience since earning highest degree). Recent trends in the representation of women and minorities among doctorate recipients and doctoral students are discussed. It is concluded that despite progress toward achieving equality, many problems remain, including the severe underepresentation of minorities and pervasive subfield segregation and pay inequities for women. (19 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
625.
The physical activation of peat moss using CO2 has been investigated with respect to the operational variables and the characteristics of the active carbon produced. Peat coke is produced during carbonisation with a 30% yield. The activated carbon accounts for 25% of the initial air dried peat moss. Analysis of the active carbon has revealed a surface area up to 600 m2/g and a chemical reactivity similar to commercial active carbon as measured by the iodine, phenazone and phenol indexes. The active carbon thus produced is a powdered material, with a weak abrasive resistance. Agglomeration of the carbon and subsequent pelletization has been done with ammonium ligno-sulfonate, water, and the application of pressure. Resistant pellets can be obtained using 15–20% lignosulfonate and 3000 psi. 相似文献
626.
627.
Vanesa Benítez Esperanza MolláMaría A. Martín-Cabrejas Yolanda AguileraFrancisco J. López-Andréu Rosa M. Esteban 《Food chemistry》2011
Food industries are forced to develop productions without secondary residues. Therefore, there is a considerable emphasis on the recovery, recycling and upgrading of wastes. The possibility has been suggested for the conversion of onion waste into food ingredients, but with a stabilisation treatment being necessary. The objective of this work was to study the effect of sterilisation on fibre fractions, fibre composition and physicochemical properties of onion by-products to evaluate the use of sterilised onion by-products as a source of fibre. 相似文献
628.
The aim of this study was to identify and characterise the predominant yeasts in Champús, a traditional Colombian cereal-based beverage with a low alcoholic content.Samples of Champús from 20 production sites in the Cauca Valley region were analysed. A total of 235 yeast isolates were identified by conventional microbiological analyses and by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) of ITS1-5.8S rDNA-ITS2. The dominant species were: Saccharomyces cerevisiae, Issatchenkia orientalis, Pichia fermentans, Pichia kluyveri var. kluyveri, Zygosaccharomyces fermentati, Torulospora delbruekii, Galactomyces geotrichum and Hanseniaspora spp. Model Champús systems were inoculated with single strains of some isolated sporogenus species and the aromatic profiles were analysed by SPME. Analysis of data showed that Champús strains produced high amounts of esters. The aromatic compounds produced by Saccharomyces and non-Saccharomyces yeasts from Champús can exert a relevant influence on the sensory characteristics of the fermented beverage. The Champús strains could thus represent an important source for new yeast biotypes with potential industrial applications. 相似文献
629.
The complexation of Cd2+, Zn2+, and both together with the phytochelatin (gamma-Glu-Cys)3Gly is studied by differential pulse polarography, and data are analyzed by multivariate curve resolution by alternating least squares (MCR-ALS). MCR-ALS yields the respective unitary voltammograms and concentration profiles of the resolved components, which contain information on the relative stabilities and stoichiometries of the formed complexes. The analysis of these results shows, for the Cd2+/(gamma-Glu-Cys)3Gly system, the presence of different kinds of bound Cd2+. For the Zn2+/ (gamma-Glu-Cys)3Gly system, the poor definition of the reduction signals of the complexes prevents a clear discrimination among differently bound Zn2+ ions. Atentative complexation/ electrochemical model is proposed for when both metal ions, Cd2+ and Zn2+, compete toward complexation, and some of the corresponding equilibrium constants are estimated. 相似文献
630.
Belenguer A. Esteban H. Boria V.E. Morro J.V. Bachiller C. 《Microwaves, Antennas & Propagation, IET》2009,3(1):62-70
A very efficient method for the accurate analysis of arbitrarily shaped H-plane two-port structures in rectangular waveguide technology is presented. The method is based on the integral-equation technique, which makes use of the Green?s function of an infinite line source placed inside two parallel plates. All the terms of the series of the Green?s function are analytically integrated, thus resulting in new series with accelerated convergence. After performing an exhaustive convergence analysis, optimal values for the parameters of this new method have been found and used in all calculations. The new method has been successfully tested after analysing several practical H-plane structures, such as inductive filters including the mechanisation effect of rounded corners. 相似文献